Publikationen:
MRT Kontrastmittel für Neuro-Imaging
Zeitschriftenartikel (58)
1.
Zeitschriftenartikel
28 (57), e202201780 (2022)
In Situ Ternary Adduct Formation of Yttrium Polyaminocarboxylates Leads to Small Molecule Capture and Activation. Chemistry – A European Journal 2.
Zeitschriftenartikel
61 (41), S. 16256 - 16265 (2022)
Insights into the Responding Modes of Highly Potent Gadolinium-Based Magnetic Resonance Imaging Probes Sensitive to Zinc Ions. Inorganic Chemistry 3.
Zeitschriftenartikel
51 (4), S. 1580 - 1593 (2022)
Stable and inert macrocyclic cobalt(II) and nickel(II) complexes with paraCEST response. Dalton Transactions 4.
Zeitschriftenartikel
155 (14), 144203, S. 1 - 11 (2021)
The effects of nitroxide structure upon 1H Overhauser dynamic nuclear polarization efficacy at ultralow-field. The Journal of Chemical Physics 5.
Zeitschriftenartikel
156 (8), 089901, S. 1 - 3 (2021)
Erratum: "The effects of nitroxide structure upon 1 H Overhauser dynamic nuclear polarization efficacy at ultralow-field". The Journal of Chemical Physics 6.
Zeitschriftenartikel
64 (11), S. 7565 - 7574 (2021)
RGD-Peptide Functionalization Affects the In Vivo Diffusion of a Responsive Trimeric MRI Contrast Agent through Interactions with Integrins. Journal of Medicinal Chemistry 7.
Zeitschriftenartikel
60 (11), S. 5734 - 5738 (2021)
Highly Potent MRI Contrast Agent Displaying Outstanding Sensitivity to Zinc Ions. Angewandte Chemie International Edition 8.
Zeitschriftenartikel
60 (3), S. 1902 - 1914 (2021)
Lanthanide(III) Complexes Based on an 18-Membered Macrocycle Containing Acetamide Pendants. Structural Characterization and paraCEST Properties. Inorganic Chemistry 9.
Zeitschriftenartikel
50 (7), S. 2448 - 2461 (2021)
Exploring the hyperpolarisation of EGTA-based ligands using SABRE. Dalton Transactions 10.
Zeitschriftenartikel
40 (1), S. 51 - 79 (2021)
Paramagnetic chemical exchange saturation transfer agents and their perspectives for application in magnetic resonance imaging. International Reviews in Physical Chemistry 11.
Zeitschriftenartikel
7 (24), S. 4121 - 4141 (2020)
Solid phase synthesis in the development of magnetic resonance imaging probes. Organic Chemistry Frontiers 12.
Zeitschriftenartikel
25 (21), E5019, S. 1 - 11 (2020)
Macrocyclic Chelates Bridged by a Diaza-Crown Ether: Towards Multinuclear Bimodal Molecular Imaging Probes. Molecules 13.
Zeitschriftenartikel
49 (17), S. 6169 - 6185 (2020)
The use of yttrium in medical imaging and therapy: historical background and future perspectives. Chemical Society Reviews 14.
Zeitschriftenartikel
56 (66), S. 9433 - 9436 (2020)
Combination of bioresponsive chelates and perfluorinated lipid nanoparticles enables in vivo MRI probe quantification. Chemical Communications 15.
Zeitschriftenartikel
7 (12), S. 2274 - 2286 (2020)
Inert macrocyclic Eu3+ complex with affirmative paraCEST features. Inorganic Chemistry Frontiers 16.
Zeitschriftenartikel
59 (12), S. 8184 - 8195 (2020)
Unexpected Trends in the Stability and Dissociation Kinetics of Lanthanide(III) Complexes with Cyclen-Based Ligands across the Lanthanide Series. Inorganic Chemistry 17.
Zeitschriftenartikel
85 (5), S. 796 (2020)
Europium(III) Macrocyclic Chelates Appended with Tyrosine‐based Chromophores and Di‐(2‐picolyl)amine‐based Receptors: Turn‐On Luminescent Chemosensors Selective to Zinc(II) Ions. ChemPlusChem 18.
Zeitschriftenartikel
85 (5), S. 806 - 814 (2020)
Europium(III) Macrocyclic Chelates Appended with Tyrosine-based Chromophores and Di-(2-picolyl)amine-based Receptors: Turn-On Luminescent Chemosensors Selective to Zinc(II) Ions. ChemPlusChem 19.
Zeitschriftenartikel
25 (7), 1709, S. 1 - 15 (2020)
Human Serum Albumin Labelled with Sterically-Hindered Nitroxides as Potential MRI Contrast Agents. Molecules 20.
Zeitschriftenartikel
56 (24), S. 3492 - 3495 (2020)
A ratiometric 19F MR-based method for the quantification of Ca2+ using responsive paramagnetic probes. Chemical Communications 21.
Zeitschriftenartikel
8 (5), S. 969 - 979 (2020)
Dendrimeric calcium-sensitive MRI probes: the first low-field relaxometric study. Journal of Materials Chemistry B 22.
Zeitschriftenartikel
5 (12), S. 1456 - 1460 (2019)
Translating a Low‐Molecular‐Weight MRI Probe Sensitive to Amino Acid Neurotransmitters into a PAMAM Dendrimer Conjugate: The Impact of Conjugation. ChemNanoMat 23.
Zeitschriftenartikel
58 (2), S. 13619 - 13630 (2019)
Toward MRI and Optical Detection of Zwitterionic Neurotransmitters: Near-Infrared Luminescent and Magnetic Properties of Macrocyclic Lanthanide(III) Complexes Appended with a Crown Ether and a Benzophenone Chromophore. Inorganic Chemistry 24.
Zeitschriftenartikel
116 (41), S. 20666 - 20671 (2019)
Early detection and monitoring of cerebral ischemia using calcium-responsive MRI probes. Proceedings of the National Academy of Sciences of the United States of America 25.
Zeitschriftenartikel
55 (79), S. 11924 - 11927 (2019)
A low-molecular-weight ditopic MRI probe for ratiometric sensing of zwitterionic amino acid neurotransmitters. Chemical Communications 26.
Zeitschriftenartikel
48 (36), S. 13546 - 13554 (2019)
Investigations into the effects of linker length elongation on the behaviour of calcium-responsive MRI probes. Dalton Transactions 27.
Zeitschriftenartikel
21 (14), S. 5378 - 5382 (2019)
Solid-Phase-Supported Approach for the Preparation of Bioresponsive and Multifunctional MRI Probes. Organic Letters 28.
Zeitschriftenartikel
7, 490, S. 1 - 12 (2019)
In-depth study of a novel class of ditopic gadolinium(III)-based MRI probes sensitive to zwitterionic neurotransmitters. Frontiers in Chemistry 29.
Zeitschriftenartikel
58 (11), S. 7571 - 7583 (2019)
Lanthanide Complexes with 1H paraCEST and 19F Response for Magnetic Resonance Imaging Applications. Inorganic Chemistry 30.
Zeitschriftenartikel
55 (28), S. 4115 - 4118 (2019)
Reinforced Ni(II)-cyclam derivatives as dual 1H/19F MRI probes. Chemical Communications 31.
Zeitschriftenartikel
25 (18), S. 4782 - 4792 (2019)
Gadolinium(III)‐Based Dual 1H/19F Magnetic Resonance Imaging Probes. Chemistry – A European Journal 32.
Zeitschriftenartikel
486, S. 252 - 260 (2019)
Water soluble Eu(III) complexes of macrocyclic triamide ligands: Structure, stability, luminescence and redox properties. Inorganica Chimica Acta 33.
Zeitschriftenartikel
92 (1093), 20180365, S. 1 - 19 (2019)
AGuIX® from bench to bedside: Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine. British Journal of Radiology 34.
Zeitschriftenartikel
19 (12), S. 4668 - 4676 (2018)
Synergy of Key Properties Promotes Dendrimer Conjugates as Prospective Ratiometric Bioresponsive Magnetic Resonance Imaging Probes. Biomacromolecules 35.
Zeitschriftenartikel
57 (10), S. 5973 - 5986 (2018)
Coordination Properties of GdDO3A-Based Model Compounds of Bioresponsive MRI Contrast Agents. Inorganic Chemistry 36.
Zeitschriftenartikel
79 (3), S. 1708 - 1721 (2018)
QUESP and QUEST revisited: fast and accurate quantitative CEST experiments. Magnetic Resonance in Medicine 37.
Zeitschriftenartikel
74 (1), S. 1 - 5 (2018)
Crystal structure of 8-(4-methylphenyl)-2′-deoxyadenosine hemihydrate. Acta Crystallographica Section E: Crystallographic Communications 38.
Zeitschriftenartikel
46 (43), S. 15095 - 15106 (2017)
Toward Inert Paramagnetic Ni(II)-Based Chemical Exchange Saturation Transfer MRI Agents. Dalton Transactions 39.
Zeitschriftenartikel
50 (9), S. 2215 - 2224 (2017)
Heading toward Macromolecular and Nanosized Bioresponsive MRI Probes for Successful Functional Imaging. Accounts of Chemical Research 40.
Zeitschriftenartikel
56 (14), S. 7737 - 7745 (2017)
Spectrally Undiscerned Isomers Might Lead to Erroneous Determination of Water Exchange Rates of paraCEST Eu(III) Agents. Inorganic Chemistry 41.
Zeitschriftenartikel
46 (2), S. 324 - 336 (2017)
Strategies for sensing neurotransmitters with responsive MRI contrast agents. Chemical Society Reviews 42.
Zeitschriftenartikel
52 (59), S. 9224 - 9227 (2016)
Paramagnetic Lanthanide Chelates for Multicontrast MRI. Chemical Communications 43.
Zeitschriftenartikel
128 (25), S. 7152 - 7161 (2016)
Biosensitive Kontrastmittel für die Magnetresonanztomographie: was wir mit ihnen wirklich tun können. Angewandte Chemie 44.
Zeitschriftenartikel
55 (25), S. 7038 - 7046 (2016)
What We Can Really Do with Bioresponsive MRI Contrast Agents. Angewandte Chemie: International Edition 45.
Zeitschriftenartikel
1 (5), S. 483 - 487 (2016)
Ratiometric Method for Rapid Monitoring of Biological Processes Using Bioresponsive MRI Contrast Agents. ACS Sensors 46.
Zeitschriftenartikel
2016 (118), S. 1 - 10 (2016)
Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging. Journal of Visualized Experiments 47.
Zeitschriftenartikel
45 (15), S. 6555 - 6565 (2016)
Synthesis and characterisation of bismacrocyclic DO3A-amide derivatives: an approach towards metal-responsive PARACEST agents. Dalton Transactions 48.
Zeitschriftenartikel
17 (4), S. 1303 - 1311 (2016)
Innovative Design of Ca-Sensitive Paramagnetic Liposomes Results in an Unprecedented Increase in Longitudinal Relaxivity. Biomacromolecules 49.
Zeitschriftenartikel
54 (21), S. 10342 - 10350 (2015)
Gd3+-Based Magnetic Resonance Imaging Contrast Agent Responsive to Zn2+. Inorganic Chemistry 50.
Zeitschriftenartikel
11 (37), S. 4900 - 4909 (2015)
Ultrasmall Nanoplatforms as Calcium-Responsive Contrast Agents for Magnetic Resonance Imaging. Small 51.
Zeitschriftenartikel
21 (31), S. 11226 - 11237 (2015)
Macrocyclic Gd(3+) complexes with pendant crown ethers designed for binding zwitterionic neurotransmitters. Chemistry – A European Journal 52.
Zeitschriftenartikel
80 (3), S. 612 - 622 (2015)
Synthesis and Characterization of a Biotinylated Multivalent Targeted Contrast Agent. ChemPlusChem 53.
Zeitschriftenartikel
56 (6), S. 759 - 765 (2015)
Synthetic strategies for preparation of cyclen-based MRI contrast agents. Tetrahedron Letters 54.
Zeitschriftenartikel
6 (2), S. 219 - 225 (2015)
MRI sensing of neurotransmitters with a crown-ether appended Gd3+ complex. ACS Chemical Neuroscience 55.
Zeitschriftenartikel
51 (14), S. 2782 - 2785 (2015)
Dendrimeric Calcium-responsive MRI Contrast Agents with Slow in vivo Diffusion. Chemical Communications 56.
Zeitschriftenartikel
20 (24), S. 7351 - 7362 (2014)
Dual-Frequency Calcium-Responsive MRI Agents. Chemistry – A European Journal 57.
Zeitschriftenartikel
5 (5), S. 360 - 369 (2014)
Investigation of a Calcium-Responsive Contrast Agent in Cellular Model Systems: Feasibility for Use as a Smart Molecular Probe in Functional MRI. ACS Chemical Neuroscience 58.
Zeitschriftenartikel
9 (1), S. 71 - 82 (2014)
Diffusion properties of conventional and calcium-sensitive MRI contrast agents in the rat cerebral cortex. Contrast Media Molecular Imaging Buchkapitel (1)
59.
Buchkapitel
Metal Ion Complexes in Paramagnetic Chemical Exchange Saturation Transfer (ParaCEST). In: Metal Ions in Bio-Imaging Techniques, 4, S. 101 - 135 (Hg. Sigel, A.; Freisinger, E.; Sigel, R.). De Gruyter, Berlin, Germany (2021)
Meeting Abstract (9)
60.
Meeting Abstract
19F MR-based Quantitative Method for Determination of Ca(II) Using Lanthanide Complexes. In 15th European Molecular Imaging Meeting (EMIM 2020), PS 14-02. 15th European Molecular Imaging Meeting (EMIM 2020), Thessaloniki, Greece, 24. August 2020 - 28. August 2020. (2020)
61.
Meeting Abstract
54 (12), 036, S. 801 - 802. Contrast Media Research Symposium (CMR 2019), Erice, Italy, 10. November 2019 - 15. November 2019. J.B. Lippincott., Philadelphia (2019)
Functional MRI of Cerebral Ischemia With a Calcium Responsive Probe. In Investigative Radiology, 62.
Meeting Abstract
Novel turn-on luminescent chemosensors selective to zinc ions. In Progressive Trends in Coordination, Bioinorganic, and Applied Inorganic Chemistry, S. 120 (Hg. Melnik, M.; Segľa, P.). XXVI. International Conference on Coordination and Bioinorganic Chemistry: Progressive Trends in Coordination, Bioinorganic, and Applied Inorganic Chemistry, Smolenice, Slovakia, 02. Juni 2019 - 07. Juni 2019. Slovak Chemical Society, Bratislava, Slovakia (2019)
63.
Meeting Abstract
Perfluorocarbon lipid nanoparticles for dual-frequency MR Neuroimaging applications. In 14th Annual Meeting of the European Society for Molecular Imaging (EMIM 2019), PS 02-03. 14th Annual Meeting of the European Society for Molecular Imaging (EMIM 2019), Glasgow, UK, 19. März 2019 - 22. März 2019. (2019)
64.
Meeting Abstract
Monitoring of calcium changes with bioresponsive MRI probes during ischemic stroke. In 14th Annual Meeting of the European Society for Molecular Imaging (EMIM 2019), PS 06-03. 14th Annual Meeting of the European Society for Molecular Imaging (EMIM 2019), Glasgow, UK, 19. März 2019 - 22. März 2019. (2019)
65.
Meeting Abstract
Investigations into calcium-responsive dendrimeric MRI contrast agents. In 7th EuCheMS Chemistry Congress (EuCheMS 2018): Molecular frontiers & global challenges, OM53. 7th EuCheMS Chemistry Congress (EuCheMS 2018): Molecular frontiers &
global challenges, Liverpool, UK, 26. August 2018 - 30. August 2018. (2018)
66.
Meeting Abstract
Nanosized Calcium-Responsive MRI Contrast Agents. In 10th Annual Meeting of the European Society for Molecular Imaging (EMIM 2015), 113. 10th Annual Meeting of the European Society for Molecular Imaging (EMIM 2015), Tübingen, Germany. (2015)
67.
Meeting Abstract
Towards the Visualization of Biological Processes Using Responsive MRI Contrast Agents. In COST Action CM1006: European f-Element Chemistry: EUFEN 3, S. 39 - 39. COST Action CM1006: European f-Element Chemistry: EUFEN 3, Nürnberg, Germany. (2014)
68.
Meeting Abstract
Dual-frequency MRI contrast agents for visualization of biological processes. In 247th ACS National Meeting and Exposition: Chemistry and Materials for Energy. 247th ACS National Meeting and Exposition: Chemistry and Materials for Energy, Dallas, TX, USA. (2014)
Vortrag (14)
69.
Vortrag
In vivo evaluation of calcium-responsive MRI probes. Université de Bordeaux: Institut de Bio-Imagerie, Bordeaux, France (2020)
70.
Vortrag
Paramagnetic and bioresponsive MRI agents. Institute of Chemical Biology and Fundamental Medicine: Siberian Branch of the Russian Academy of Sciences , Novosibirsk, Russia (2019)
71.
Vortrag
Biocompatible macromolecular conjugates for hyperpolarized MRI applications. Annual Conference of the Architects of Nano-hybrid Compounds: Toward Material and Biological Applications (Nanohybrides 16), Porquerolles Island, France (2019)
72.
Vortrag
Exploiting Chemistry Probes for Molecular fMRI. University of York: Department of Chemistry, Heslington, UK (2018)
73.
Vortrag
Design and characterization of molecular sensors for functional MRI applications. XXXII Convegno Nuovi Orientamenti Sintesi Organica, Milano, Italy (2017)
74.
Vortrag
Bioresponsive Nanosized Probes for Functional MRI Applications. CIC biomaGUNE: Center for Cooperative Research in Biomaterials, San Sebastián, Spain (2017)
75.
Vortrag
Bioresponsive MRI Agents: Insights from Coordination Chemistry. 42nd International Conference on Coordination Chemistry (ICCC 2016), Brest, France (2016)
76.
Vortrag
Bioresponsive contrast agents for functional MRI: From small to nanosized molecular probes. Munich Symposium on Molecular Devices, Neurons, Circuits Brains, München, Germany (2016)
77.
Vortrag
Bioresponsive Nano-sized Contrast Agents for Functional MRI. Conference on Medicinal Flavor of Metal Complexes: Diagnostic and Therapeutic Applications, Orléans, France (2015)
78.
Vortrag
Bioresponsive Nano-sized Probes for Functional MRI Applications. Bioorganik 2015, Hamburg, Germany (2015)
79.
Vortrag
Bioresponsive nano-sized probes for functional MRI applications. Final Annual Meeting COST Action TD1004: Theranostics Imaging and Therapy: An Action to Develop Novel Nanosized Systems for Imaging-Guided Drug Delivery, Beograd, Serbia (2015)
80.
Vortrag
Synthesis of bismacrocyclic smart contrast agents (SCAs) using solid phase techniques. Final Annual Meeting COST Action TD1004: Theranostics Imaging and Therapy: An Action to Develop Novel Nanosized Systems for Imaging-Guided Drug Delivery, Beograd, Serbia (2015)
81.
Vortrag
Calcium-responsive MRI Agents: Insights from Coordination Chemistry. Symposium „Quo Vadis” Coordination Chemistry? (A quick view of Imre Tóth’s friends in 2015) , Debrecen, Hungary (2015)
82.
Vortrag
Towards the Visualization of Biological Processes with Responsive MRI Contrast Agents. Christian-Albrechts-Universität: GDCh-Kolloquium, Kiel, Germany (2014)
Poster (12)
83.
Poster
The effects of nitroxide structure upon Overhauser dynamic nuclear polarization efficacy at ultralow-field. 16th Annual Meeting of the European Society for Molecular Imaging (EMIM 2021), Göttingen, Germany (2021)
84.
Poster
Nanosized free radicals for the use as contrast and hyperpolarization agents in ultralow-field and high-field MRI. 16th Annual Meeting of the European Society for Molecular Imaging (EMIM 2021), Göttingen, Germany (2021)
85.
Poster
Early Detection and Monitoring of Cerebral Ischemia Using a Calcium Responsive MRI Probe. FENS Regional Meeting 2019, Beograd, Serbia (2019)
86.
Poster
Monitoring of ischemic stroke with calcium-responsive MR contrast agents. 11th Annual World Molecular Imaging Congress (WMIC 2018), Seattle, WA, USA (2018)
87.
Poster
QUESP and QUEST revisited: a more complete theory for quantification of chemical exchange saturation transfer experiments. 34th Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB 2017), Barcelona, Spain (2017)
88.
Poster
Deciphering the functional projections of the lateral hypothalamus with optogenetic fMRI. 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017), Honolulu, HI, USA (2017)
89.
Poster
A Ratiometric Bioresponsive MRI Contrast Agent for Rapid Monitoring of Biological Processes. 24th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2016), Singapore (2016)
90.
Poster
Dynamic MRI ratiometric signal reporting by exploiting dendrimeric calcium-responsive contrast agent. Final Annual Meeting COST Action TD1004: Theranostics Imaging and Therapy: An Action to Develop Novel Nanosized Systems for Imaging-Guided Drug Delivery, Beograd, Serbia (2015)
91.
Poster
Improved liposomes-based Ca(II) responsive MRI contrast agents. 23rd Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2015), Toronto, Canada (2015)
92.
Poster
Improved liposomes-based Ca(II) responsive MRI contrast agents. 10th Annual Meeting of the European Society for Molecular Imaging (EMIM 2015), Tübingen, Germany (2015)
93.
Poster
Synthesis of High Affinity Agents for Targeted MR Neuroimaging. COST Action CM1006: European f-Element Chemistry: EUFEN 3, Nürnberg, Germany (2014)
94.
Poster
Synthesis of High Affinity Agents for Targeted MR Neuroimaging. COST Action CM1006: European f-Element Chemistry: EUFEN 3, Nürnberg, Germany (2014)
Hochschulschrift - Doktorarbeit (1)
95.
Hochschulschrift - Doktorarbeit
Synthesis and Characterisation of Multifunctional Bioresponsive Magnetic Resonance Imaging Probes. Dissertation, 184 S., Eberhard-Karls-Universität, Tübingen, Germany (2019)