Forschungsinteressen
LIST OF GRANTS AND FUNDING
KLAUS SCHEFFLER, PhD
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1) DFG (German Federal Research Foundation)
2002 SCHE 658. K. Scheffler, J. Hennig. Development and test of contrast modified TrueFISP sequences.
Support: 2 years BAT2a + 1 year BAT2a/2
2002 HE 1875/12-1. J. Hennig , K. Scheffler. Theorie des Kernresonanzsignals in lebendem Gewebe.
Support: 2 years BAT2a
2011 DFG CIN Pool Project Application. Berg, K. Scheffler. Magnetic resoncance spectroscopy imaging MRSI: substantianigra: Parkinson´s disease.
Support Postdoc stipend for 12 month (about EUR 16.000)
2012 DFG SCHE 658/2-1 K. Scheffler. Advanced biochemical Magnetic Resonance Imaging on high and ultrahigh magnetic field strength (3 and 7 Tesla): Visualization of early degenerative cartilage disease in the knee joint by means of noncontrast glycosaminogylcan specific multi-parametric MR imaging.
Support EUR 115.290)
2013 DFG SCHE 658/5-1 K. Scheffler. VR-System zur visuohaptischen Stimulation bei fMRT Untersuchungen
Support EUR 187.866 for 3 years
2014 DFG SCHE 658/7-1 K. Scheffler. Messung neuronaler Aktivität mit kombinierten, multifunktionalen Mikro NMR Proben und Mikroelektroden.
Support EUR 223.200 for 3 years
2014 INST 2388/53/1 FUGG, Forschungsgrossgerät nach Art. 91b GG K. Scheffler. 3T Siemens Prisma scanner.
Support EUR 2.250.000 for 5 years (50% DFG, 50% State of Baden-Würtemberg)
2017 Reinhart Koselleck-Projekt DFG SCHE 658/12 K. Scheffler. TrueBOLD: Detection of brain activity with TrueFISP.
Support EUR 1.220.000 for 5 years.
2017 DFG SCHE 658/13-1 K. Scheffler. Ein neuartiges Shimsystem optimiert für die Anatomie des menschlichen Kopfes.
Support EUR 83.050 for 1 year.
2) Helmholtz-BMBF
2012 ICEMED-HA314. K. Scheffler, J. Hennig. Imaging and Curing Environmental Metabolic Diseases
Support: EUR 525.000 for 5 years
2017 MR-Implant. Förderantrag im Rahmen der Richtlinie: "Neue Elektroniksysteme für intelligente Medizintechnik (Smart Health)".
M. Schüttler, M. Ortmans, K. Scheffler, F. Ohnhäuser.
Support: EUR 2.138.880 for 3 years.
2017 Collaborative Research in Computational Neuroscience (CNRS). Deciphering the laminar-specific functional connectivity and its vascular and neural correlates. B. Biswal, X. Yu, K. Scheffler.
Support: EUR 721.121.40 for 3 years
3) SNSF (Swiss national science foundation)
2000 SNF 3100-056477.99/1. D. Bilecen, E.W. Radü, K. Scheffler, E. Seifritz, R. Probst. Functional MR imaging of the human auditory system.
Support: CHF 140.000
2000 SNF 3200-059202.99/1. M. Rausch, E.W. Radü, M. Rudin, K. Scheffler. Delineation of infarct and penumbra after ischemic brain injuries by visualization of macrophage activity and perfusion with magnetic resonance imaging in human and rats.
Support CHF 140.000
2002 SNF 3200-066634.01. S. Wetzel, K. Scheffler, E.W. Radü. Chronic cerebral hypoperfusion in carotid steno-occlusive disease: Assessment with MR imaging.
Support CHF 133.400
2003 SNF PP0B-68783/1. K. Scheffler. Förderungsprofessur des Schweizerischer Nationalfonds SNF. Magnetic resonance imaging for non-invasive characterization of living tissue using parametric and steady-state free precession (SSFP) approaches.
Support CHF 1.239.433/4 years
2003 SNF 3100A0-100633/1. D. Bilecen, E.W. Radü, K. Scheffler, E. Seifritz, R. Probst. BOLD-fMRI of the Human Auditory Cortex.
Support CHF 127.000
2006 SNF 3200B0-113897. P. Weber, IK Penner, K. Scheffler, J. Lütschg. Functional networks of working memory in children with epilepsy in frontal or extra-frontal regions and combined attention deficit /hyperactivity disorder in comparison to children with developmental attention deficit/hyperactivity disorder.
Support CHF 260.000
2006 SNF 320000-113492. S. Wetzel, P. Lyrer, K. Scheffler. Assessment of Intracranial Arterial Hemodynamics with Flow Sensitized 4D MRI.
Support CHF 191.000
2007 SNF 32500-118377. K. Scheffler, O. Bieri. Development of new magneic resonance acquisition concepts for magnetization transfer and oscillating steady state imaging.
Support CHF 283.300
2009 SNF CR23I2_125406. B. Müller, M. Müller-Gerbl, K. Scheffler , Ph. Cattin Franz Pfeiffer. High-resolution 3D imaging of the human brain post mortem.
Support CHF 312'968
2009 SNF CR32I3_125499. Ch. Becker, K. Scheffler, S. Terraz, Ph. Cattin, R. Salomir. Experimental and clinical validation of a fully integrated platform of MRI guided focused ultrasound thermotherapy in moving organs
Support CHF 500000
2009 Sinergia . Cattin, R. Salomir, K. Scheffler, S. Terraz, Ph. Evaluation and Validation of Ultrasound for the Management of Organ Motion in Tumour Therapy.
Support CHF 800000
2009 SNF 320030_127079 . Haller S., K. Scheffler. Clinical applications of real time functional magnetic resonance imaging (rtfMRI) biofeedback.
Support CHF 291988
2009 REQUIP SNF 316030_128818 . K. Scheffler, C. Stippich, C. Beglingen, A. Gass. Multi Nucleus Support and RF Coils for 3T Magnetic Resonance Scanner.
Support CHF 150000
2009 NCCR CO-ME . Zeilhofer, Vetter, Cattin, Scheffler, Mazza, Gross, Reyes, Baur. Computer aided and image guided medical interventions.
Support CHF 1'550'720 (own (CHF 190'000)
2010 SNF 310030_130689. Ch. Cajochen, K. Scheffler. Cerebral mechanisms underlying the influence of age-related changes in circadian and homeostatic processes on cognition: a functional neuroimaging approach.
Support CHF 528'954
2010 SNF CR31I3_130672. Jhooti P, Torpuls J, Tuch A, K. Scheffler. The use of biofeedback for user-centeredapproaches in MRI
Support CHF 167'005
2010 SNF 325230_132906. Bieri O, K. Scheffler Development of fast quantitative diffusion and transverse relaxation time magnetic resonance steady state imaging concepts for living tissues
Support CHF 294'604
2011 SNF 320030E-134474 DACH. S. Trattnig, K. Scheffler Advanced biochemical Magnetic Resonance Imaging on high and ultrahigh magnetic field strength (3 and 7 Tesla): Visualization of early degenerative cartilage disease in the knee joint by means of noncontrast glycosaminogylcan specific multi-parametric MR imaging.
Support CHF 60'000
4) EU
2006 EU FP6-2004-NEST-C-1 Grant 028433. , J. Hennig, K. Scheffler, J. Korvink, S. Popovic, A. Jasinski, H. Post. MICRO-MR: Development of Magnetic Resonance Measurement System for the Examination, Characterisation and in vitro- and in vivo Observation of Probes on a Micrometer Scale
Support total EUR 1.799.000
2009 EU-Bildungsprogrammes "Leonardo da Vinci StudEx den Stipendium
Support CHF 4.500
2009 EU-Bildungsprogrammes "Leonardo da Vinci StudEx den Stipendium
Support CHF 4.500
2009 EU FP7 Cooperation Health, ENCITE, European Network for Cell Imaging and Tracking Expertise, Grant 201842.
Support total EUR 11.997.000
2015 H2020-PHC-2014, Advancing bioinformatics to meet biomedical and clinical needs CDS-QUAMRI, A. Henning, G. Lohmann, K. Borgwardt, MJ van Osch, C WheelerlKingshott, S Grimm, G CrelierEuropean Network for Cell Imaging and Tracking Expertise, Grant 634541.
Support total EUR 2.168.125
2015 H2020-PHC-11-2015, GLINT: GlucoCEST Imaging of Neoplastic Tumours. X. Golay, G. Navon, S. Aime, K. Scheffler, O. Axesson, A. Mitulescu, S Grimm, G Crelier. Grant 667510-2.
Support total: EUR 6.454.612, (own support EUR 637.537)
5) Trinational grant
2003 NEUREX/Eltem Exchange PhD grant. K. Scheffler, J. Hennig. Mapping of (neuronal) currents be means of T1r-sensitive magnetic resonance imaging.
Support CHF 84.000
6) Internal University of Tübingen Grants
2010 CIN1 Intramural Research Grant: Investigations of biomolecular changes within the substantia nigra in patients with Parkinson's diseases using 3D MRSI Gröger, Berg, Scheffler.
Support EUR 32.760
2011 CIN1 Intramural Research Grant: Multimodal spike localization in non-lesional focal epilepsies and correlation to cognitive deficits. Lerche, Preissl, Scheffler.
Support EUR 40.810
2012 CIN2 Intramural Research Grant: Functional neuroimaging of the human tectum at 9,4 T. Himmelbach, Ethofer, Hagberg.
Support 1 PhD stipend for 2 years plus EUR 7100
2012 CIN2 Intramural Research Grant: Functional imaging laminar and columnar functional organization of higj-level visual motion processing areas in humans. Bartels, Scheffler
Support PhD stipend for 2 years plus EUR 16460
2012 CIN2 Intramural Research Grant: Evalating voxel.based functional connectivity measures in epilepsy Focke, Scheffler
Support PhD stipend for 2 years plus EUR 5500
2013 Fortüne-Antrag Nr. 2197-0-0 A novel approach to assess an extended biochemical profile of the human brain by the means of fast and efficient in-vivo proton magnetic resonance spectroscopy imaging at 9.4T
Support 2 Jahre E13
7) Nachwuchsförderungsprogramm des Bundes, Bern
2002 Assistant Professor ship in Medical Physics. Position No 1305. K. Scheffler
Support 2 years
8) Foundation
2004 Schweizerische Stiftung für Neuropsychiatrische Forschung. K Cattapan-Ludewig, E. Seifritz Scheffler K. Scheffler. Music in the brain: Neuronal plasticity and intersubject synchronization - A
functional and structural MRI study with musicians and non-musicians
Support CHF 180.000
2005 Fonds zur Förderung von Lehre und Forschung. K. Scheffler.
Support CHF 52.900
2008 Fonds zur Förderung von Lehre und Forschung. K. Scheffler.
Support CHF 50.000
2010 Gottfried und Julia Bangerter-Rhyner-Stiftung. K. Scheffler.
Support CHF 27.500
9) SOCIETIES
2009 Swiss MS Society. Entwicklung eines standardisierten Verfahrens für die Vergleichbarkeit von MR Magnetisierungstransfer Aufnahmen verschiedener Gerätetypen. O. Bieri, S. Wetzel, K. Scheffler.
Support CHF 55.000
2011 Swiss MS Society. Advanced MR techniques (Quantitative Magnetization Transfer and Diffusion Tensor Imaging) for increased image sensitivity in Multiple Sclerosis. Garcia M, Lenz C, Gloor M, Bieri O, Scheffler K, Stippich Ch, Kappos L, Radü EW.
Support CHF 50.000 for 2 years
10) KTI/CTI
2005 MR-compatible, synthetic guide wire in cooperation with Siemens Medical Solution and Biotronik AG. D. Bilecen, E. Hofmann, H. Schmid, K. Scheffler.
Support: CHF 210.000
11) Industry
2003 Cooperation Siemens Medical Solution. K. Scheffler. Installation of a 1.5 T MR scanner for research.
MR scan time: 4 days/week for MR-Physik
2003 Cooperation Siemens Medical Solution. K. Scheffler. Development if interventional MR techniques.
Support EUR 90.000
2004 Cooperation Novartis. K. Scheffler.
Support EUR 6.000
2005 Cooperation Siemens Medical Solution. K. Scheffler. Installation of a 3T research MR scanner.
MR scan time: 2 days/week for MR-Physik
2004 Cooperation Novartis. K. Scheffler. Financial support for 3T MR scanner.
Pro rata support EUR 133.000
2005 Cooperation Siemens Medical Solution. K. Scheffler. Development if interventional MR and move during scan techniques.
Support EUR 95.000
2005 Cooperation GE-Amersham. K. Scheffler.
Support EUR 22.000
2007 Cooperation Novartis. K. Scheffler. Magnetization Transfer Imaging.
Support CHF 275.000
2007 Cooperation Siemens Medical Solution. K. Scheffler.
Support CHF 810.000
2009 Cooperation Novartis. K. Scheffler. CSF flow imaging.
Support CHF 55.000
2009 Cooperation Novartis. K. Scheffler. CBAF312A2201.
Support CHF 41.159
2009 Cooperation Siemens. K. Scheffler. CSF flow imaging.
Support CHF 124.000
2010 Cooperation Novartis. K. Scheffler, P. Buser Non-invasive Measurement of Pulmonary Artery Pressure with Magnetic Resonance Imaging: A Method Evaluation Study.
Support CHF 198.000
2010 Cooperation Siemens. K. Scheffler. Projektvertrag 5
Support CHF 64.000
2010 Cooperation Roche Diabetes. K. Scheffler Machbarkeitsstudie um die Verteilung von subkutan injizierten Flüssigkeiten über die Magnetresonanztomographie festzuhalten.
Support CHF 13.665
Vita
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---------------------------------------------------------------------------------------------------------------------------------------------------------- CURRICULUM VITAE KLAUS SCHEFFLER, PhD ---------------------------------------------------------------------------------------------------------------------------------------------------------- |
| Name | Klaus Scheffler, PhD |
| Present position | Director Department of Biomedical Magnetic Resonance, Medical Faculty, University of Tübingen Max Planck Fellow Head of MRC Department Max Planck Institute for Biological Cybernetics |
| Academic Degree | Prof. Dr. phil. Professor (W3 chair) of Neuroimaging and MR Physics at the Medical Faculty of the University of Tübingen |
| Laboratory address | MRC Department Max Planck Institute for Biological Cybernetics Spemannstrasse 41 72076 Tübingen, Germany |
| URL | klaus.scheffler@tuebingen.mpg.de http://www.kyb.tuebingen.mpg.de/de/forschung/abt/ks.html |
| Phone/Fax | +49 7071 601 701 / 702 |
Education
| 1984 | Matura | Kepler-Gymnasium, Tübingen, Germany |
| 1986 | Emergency Medical Technician | 20 month obligatory Federal Civilian Service, Tübingen, Germany |
| 1992 | Dipl. Phys. (Master in Physics) | Physics Department of the University of Freiburg, Germany. Diploma-Thesis in Theoretical Physics: Inverse Probleme in der Bildverarbeitung. Supervisor: Prof. J. Honerkamp |
| 1995 | Dr. phil. II (PhD in Biophysical Chemistry) | Department of Biochphysical Chemsitry, Biozentrum, University of Basel. PhD-Thesis in Biophysical Chemistry: Optimierung modulierter Hochfrequenzpulse und Reguläre und stochastische k-Raum Trajektorien in der Kernresonanz-Bildgebung. Summa Cum Laude. Supervisor: Prof. J. Seelig, Basel and Prof. J. Hennig, Freiburg,Germany |
| 2002 | Habil. Med. Phys. | Habilitation in Medical Physics at the Medical Faculty of the University of Freiburg, Germany |
| 2003 | Habil. Med. Phys. | Habilitation in Medical Physics at the Medical Faculty of the University of Basel |
Postdoctoral training
| 1995 | Department of Biochphysical Chemsitry, Biozentrum and MR-Zentrum, University of Basel |
| 1999 | Section of Medical Physics, Department of Radiology, University of Freiburg, Germany |
Academic appointments
| 2002 | Assistant Professor in Medical Physics at the University of Basel. (Nachwuchsförderungsprogramm des Bundes) |
| 2003 | Swiss National Science Foundation (SNSF) Award Professor, Department of Medical Radiology, University of Basel, University Hospital. |
| 2006 | Visiting Professor, Johns Hopkins University, Baltimore, MA |
| 2006 | Visiting Professor, Mayo Clinic, Rochester, MN |
| 2008 | Appointment to Full Professor of Radiological Physics at the University of Basel |
| 2011 | Max Planck Fellow, MPI for Biological Cybernetics, Tübingen |
| 2011 | Full Professor (W3 Chair) of Neuroimaging, University of Tübingen |
Institutional appointments
| 1995 | Senior Research Assistant and Teaching Assistant, MR-Zentrum (Prof. J. Seelig), Biozentrum at the University of Basel |
| 1999 | Senior Research Associate, Section of Medical Physics (Prof. J. Hennig), University of Freiburg, Germany |
| 2002 | Head MR-Physics Reseaqrch Group, Department of Medical Radiology, University Hospital and University of Basel |
| 2008 | Director of Division of Radiological Physics, University Hospital Basel |
| 2011 | Head of MRZ Department at the Max-Planck-Institute for Biological Cybernetics, Tübingen |
| 2011 | Director of the Department of Neuroimaging, Werner Reichardt Center for Integrative Neurosciences, University of Tübingen. |
Organisationseinheit (Abteilung, Gruppe, Einrichtung):
- Department High-field Magnetic Resonance