DSSS - Building, maintaining and discarding large macromolecular assemblies during gametogenesis
- Date: Feb 17, 2023
- Time: 03:00 PM - 04:00 PM (Local Time Germany)
- Speaker: Prof. Dr. Joao Matos
- Department of Chromosome Biology Max Perutz Labs - VBCI University of Vienna
- Location: MPI für Biologie, Max-Planck-Ring 5, room 0A01
The life cycle of sexually reproducing eukaryotes depends on two specialised chromosome segregation programs: mitosis and meiosis. Whereas mitosis drives cellular proliferation and the stable propagation of the genome, meiosis promotes genetic diversity and the formation of rejuvenated gametes, which combine at fertilisation to restore the diploid state. I will discuss how meiotic cells build, maintain and disassemble/segregate/discard three macromolecular assemblies during meiosis: i) the synaptonemal complex; ii) two novel filamentous structures that are important for cell viability after gametogenesis and for gamete rejuvenation.