Anagha Deshmane

Anagha Deshmane

Postdoc
Department High-field Magnetic Resonance
+49 7071 601 945
+49 7071 601 702
3.A.02

Main Focus

My research interests focus on development of fast and quantitative magnetic resonance imaging (MRI) techniques which may enable or enhance diagnosis and monitoring of treatment response in clinical settings.

At the Max Planck Institute for Biological Cybernetics, I have recently joined the , aimed at investigating metabolism in brain tumors.  My role is to develop fast protocols for imaging hydroxel groups and proteins using chemical exchange saturation transfer (CEST) MRI at 9.4T and to develop improved translated protocols for use at clinical field strengths.

My previous research involved development of Magnetic Resonance Fingerprinting, a fast imaging technique for quantifying MR relaxation times, system/experimental parameters, and tissue composition (partial volume effects) in the brain.

Curriculum Vitae

Degrees:

May 2017 PhD, Biomedical Engineering
Case Western Reserve University (Cleveland, OH, USA)
Dissertation: Partial Volume Quantification Using Magnetic Resonance Fingerprinting

Sept 2009 MEng, Electrical Engineering & Computer Science
Massachusetts Institute of Technology (Cambridge, MA, USA)
Thesis: False Arrhythmia Alarm Suppression Using ECG, ABP, and Photoplethysmogram

June 2008 BS, Electrical Engineering
Massachusetts Institute of Technology (Cambridge, MA, USA)

Fellowships:

2012-2013 Fellow, Whitaker International Fellows & Scholars Program
Host: Dept. Experimental Physics V, Würzburg, Germany

2010-2012 Trainee, NIH T32 Interdisciplinary Biomedical Imaging Training Program
Case Western Reserve University Dept. Biomedical Engineering (Cleveland, OH, USA)

2008-2009 Fellow, Charles Stark Draper Laboratory (Cambridge, MA, USA)

Honors & Awards:

2017 Magna Cum Laude Merit Award, International Society of Magnetic Resonance in Medicine (p.132)
2014 Summa Cum Laude Merit Award, International Society of Magnetic Resonance in Medicine (p. 94)

Key Publications:

  • Deshmane A, Ma D, McGivney D, Jiang Y, Badve C, Gulani V, Seiberlich N, Griswold M. Partial Volume Mapping Using Magnetic Resonance Fingerprinting (PV-MRF). NMR in Biomedicine, in press; 2019.
  • Zaiss M, Deshmane A, Schuppert M, Herz K, Ehses P, Lindig T, Bender B, Ernemann U, Scheffler K. DeepCEST: 9.4T Chemical Exchange Saturation Transfer MRI contrast predicted from 3T data - a proof of concept study. Magnetic Resonance in Medicine, in press; 2019. Preprint: https://arxiv.org/abs/1808.10190
  • Deshmane A, Zaiss M, Lindig T, Herz K, Schuppert M, Gandhi C, Bender B, Ernemann U, Scheffler K. 3D gradient echo snapshot CEST MRI with low power saturation for human studies at 3T. Magnetic Resonance in Medicine, in press; 2018. https://doi.org/10.1002/mrm.27569
  • Ma D, Jones S, Deshmane A, Sakaie K, Pierre E, McGivney D, Lowe M, Gulani V, Najm I, Griswold M, Wang I. Development of High-resolution 3D MR Fingerprinting for Detection and Characterization of Epileptic Lesions. Journal of Magnetic Resonance Imaging, in press; 2018. https://doi.org/10.1002/jmri.26319
  • Yu A, Deshmane A, Dastmalchian S, Cohen M, Ma D, Sunshine J, Gulani V, Griswold M, Sloan M, Badve C. In Vivo Tissue Characterization of Focal Nodular Heterotopia using Magnetic Resonance Fingerprinting. Neurographics, in press; 2018.
  • McGivney D, Deshmane A, Jiang Y, Ma D, Badve C, Sloan A, Gulani V, Griswold M. Bayesian Estimation of Multicomponent Relaxation Parameters in Magnetic Resonance Fingerprinting. Magnetic Resonance in Medicine 80(1):159-170; 2018.
  • Deshmane A, Blaimer M, Breuer F, Jakob P, Duerk J, Seiberlich N, Griswold M.  Self-calibrated Trajectory Estimation and Signal Correction Method for Robust Radial Imaging Using GRAPPA Operator Gridding (GROG).  Magnetic Resonance in Medicine, 75(2):883-896; 2016.
  • Deshmane A, Gulani V, Griswold MA, Seiberlich N. Parallel MR Imaging. Journal of Magnetic Resonance Imaging, 36(1):55-72; 2012.

Recent Conference Participation:

  • Ma D, Wang I, Najm I, Deshmane A, McGivney D, Sakaie K, Lowe M, Gulani V, Griswold M, Jones S. Using 3D high-resolution MR Fingerprinting (MRF) to assist detection and characterization of epileptic lesions. In Proceedings of the 26th Annual Meeting of the International Society of Magnetic Resonance in Medicine, Paris, France, 2018. p. 315. Oral (Power Pitch).
  • Zaiss M, Deshmane A, Herz K, Braun M, Bender B, Lindig T, Scheffler K. Deep CEST MRI – 9.4T spectral super-resolution from 3T CEST MRI data. In Proceedings of the 26th Annual Meeting of the International Society of Magnetic Resonance in Medicine, Paris, France, 2018. p. 414. Oral.
  • Schuppert M, Herz K, Deshmane A, Zaiss M. Novel contrasts at +2.7ppm, +1.2ppm, and -1.7ppm investigated in vivo with high spectral resolution CEST MRI in the human brain at 9.4T. In Proceedings of the 26th Annual Meeting of the International Society of Magnetic Resonance in Medicine, Paris, France, 2018. p. 558. Oral (Power Pitch).
  • Zaiss M, Bause J, Deshmane A, Herz K, Scheffler K. 3D CEST MRI of human brain at 9.4T reveals vessel correlation of the effect at -1.7ppm. In Proceedings of the 26th Annual Meeting of the International Society of Magnetic Resonance in Medicine, Paris, France, 2018. p. 2224. Poster.
  • Gandhi C, Longo D, Anemone A, Herz K, Deshmane A, Lindig T, Bender B, Aime S, Scheffler K, Zaiss M. Optimization of OH-CEST contrast at 3T for clinical application of glucoCEST MRI. In Proceedings of the 26th Annual Meeting of the International Society of Magnetic Resonance in Medicine, Paris, France, 2018. p. 2233. Poster.
  • Deshmane A, Zaiss M, Bender B, Lindig T, Windschuh J, Herz K, Scheffler K. Low power Z-spectrum analysis for isolated NOE and amide CEST-MRI at 3T with comparison to 9.4T. In Proceedings of the 26th Annual Meeting of the International Society of Magnetic Resonance in Medicine, Paris, France, 2018. p. 2249. Poster.
  • Deshmane A, McGivney D, Badve C, Gulani V, Griswold M.  Dictionary approach to partial volume estimation with MR Fingerprinting: Validation and application to brain tumor segmentation. In Proceedings of the 25th Annual Meeting of International Society of Magnetic Resonance in Medicine, Honolulu, HI, USA, 2017. p 132.  Oral (Power Pitch)
  • Deshmane A, McGivney D, Jiang Y, Ma D, Griswold M. Proton Density Mapping and Receiver Bias Correction for Absolute Quantification with MR Fingerprinting. In Proceedings of the 25th Annual Meeting of International Society of Magnetic Resonance in Medicine, Honolulu, HI, USA, 2017. p 1614. Poster.
  • McGivney D, Deshmane A, Jiang Y, Ma D, Griswold M. Analyzing the Bayesian Approach to Partial Volume in MRF. In Proceedings of the 25th Annual Meeting of International Society of Magnetic Resonance in Medicine, Honolulu, HI, USA, 2017. p 1611. Poster.
  • McGivney D, Deshmane A, Badve C, Ma D, Gulani V, Griswold M. Exploring Subvoxel Structures in Brain Tumors using Magnetic Resonance Fingerprinting. In Proceedings of the 25th Annual Meeting of International Society of Magnetic Resonance in Medicine, Honolulu, HI, USA, 2017. p 4696. ePoster.
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