Amygdala circuitry in reward learning & decision making
- Date: Apr 11, 2022
- Time: 05:00 PM - 06:00 PM (Local Time Germany)
- Speaker: Kate Wassum
- Professor, Wenzel/Jeffrey Term Chair in Behavioral Neuroscience, UCLA; Department of Psychology, Brain Research Institute, Integrative Center for Learning & Memory, Integrative Center for Addictive Disorders
- Location: Zoom
- Host: Peter Dayan (Philipp Schwartenbeck)
To make adaptive decisions we must cast ourselves into the future and consider the outcomes of our potential choices. This prospective consideration is informed by our memories. I will discuss our lab’s recent work investigating the neural circuits responsible for encoding, updating, and retrieving reward memories for use in the considerations underlying decision making. We have taken a multifaceted approach to these investigations, combining recording, modern circuit dissection, and behavioral tools. Our results are generally indicating that the basolateral amygdala, midbrain, and orbitofrontal cortex work in a circuit to participate in these functions. The cognitive symptoms underlying many psychiatric disorders result from a failure to appropriately learn about and/or anticipate potential future events, making these basic science data relevant to the understanding and potential treatment of mental illness.