Research Group Leader

Dr. Xin Yu
Dr. Xin Yu
Phone: +49 7071 601-740
Fax: +49 7071 601-701
xin.yu[at]tuebingen.mpg.de

 

1 Vascular Dynamic Network Connectivity Study

Supplementary Video1


Supplementary Video 1: The seed-based bSSFP BOLD rsfMRI in the rat brain.
The white arrow indicates the location of the seed (radius: 150 um). When the seed was moved to dark dots (venule voxels),
most venule voxels were highly correlated but less so for arteriole voxels.

Supplementary Video2

Supplementary Video 2: The seed-based bSSFP CBV rsfMRI in the rat brain.
The white arrow indicates the position of the seed (radius: 150 um). When the seed was moved to bright dots (arteriole voxels),
most arteriole voxels were highly correlated but less so for venule voxels.

Supplementary Video3

Supplementary Video 3: The evoked BOLD fMRI signal with voxel-wise time courses in the human brain.
With the visual stimulation (8 Hz checkerboard), the voxel-wise BOLD fMRI signal changes (left panel) were demonstrated from
5x5 voxel matrix covering one individual vein through suclus (the dark voxel in the green square, middle panel). The red cursor
moved in the center voxel corresponding to the color-coded BOLD functional movie (right panel).

Supplementary Video4


Supplementary Video 4: The seed-based rsfMRI in the human brain.
The white arrow indicates the location of the seed (radius: 1 mm). The seed-based correlation maps by resting-state fMRI
demonstrated vein-dominated correlation spatial patterns.

Supplementary Video5

Supplementary Video 5: Vascular dynamic network connectivity using ICA Analysis in human at resting state.
The left panel exhibits the ICA-based correlation maps with the averaged EPI images as the background (dark voxels as veins).
The video demonstrates the highly correlated venous voxels at multiple slices, showing a 3D vascular dynamic correlation structure
(Z-scores > 1.5) through the main branches of the cerebrovasculature.
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
______________________________________________________________________________________________________________________________________________________________________________________________________

2 Single-vessel line-scanning fMRI study

Rat forepaw somatosensory cortex single-vessel fMRI:

Individual venules BOLD fMRI

Individual arterioles CBV fMRI


3 Coma study

A LFP comparison of anesthetized and unconscious rats.

LFP in anesthetized rats

 

LFP under different isoflurane levels. Top, spectrogram. Middle, raw signal. Bottom, signal part marked by the red frame.

 
 
                                                          

LFP recorded during the transition of isoflurane levels from 1.0% to 2.5%. Top, spectrogram. Middle, raw signal. Bottom, signal part marked by the red frame.

 
 

LFP in uncoscious rats



 

LFP of an unconscious rat during different post-surgery time periods. Top. spectrogram. Middle, raw signal. Bottom, signal part marked by the red frame.

Last updated: Thursday, 09.02.2017