Looking for Participants

The MPI for Biological Cybernetics is looking for participants for some of their research experiments [more].
 

Most recent Publications

Göksu C, Hanson LG, Siebner HR, Ehses P, Scheffler K and Thielscher A (May-2018) Human in-vivo brain magnetic resonance current density imaging (MRCDI) NeuroImage 171 26-39.
Nassirpour S, Chang P, Fillmer A and Henning A (February-2018) A comparison of optimization algorithms for localized in vivo B0 shimming Magnetic Resonance in Medicine 79(2) 1145–1156.
Cleij D, Venrooij J, Pretto P, Pool DM, Mulder M and Bülthoff HH (February-2018) Continuous Subjective Rating of Perceived Motion Incongruence During Driving Simulation IEEE Transactions on Human-Machine Systems 48(1) 17-29.
Avdievich NI, Giapitzakis I-A, Pfrommer A and Henning A (February-2018) Decoupling of a tight-fit transceiver phased array for human brain imaging at 9.4T: Loop overlapping rediscovered Magnetic Resonance in Medicine 79(2) 1200–1211.
Arena C, Irrera P, Consolino L, Colombo Serra S, Zaiss M and Longo DL (February-2018) Flip-angle based ratiometric approach for pulsed CEST-MRI pH imaging Journal of Magnetic Resonance 287 1–9.

 

The Research Groups and their Research Focus

MR Spectroscopy and Ultra-High Field Methodology

Magnetic Resonance Spectroscopy (MRS) allows for non-invasive and non-ionizing determination of tissue concentrations and metabolic turn-over rates of various metabolites and compounds in animals or humans. MRS is hence applied for clinical diagnostics and has established as an important tool for physiological research. The focus of this research group is MRS methods development exploiting the advantages of ultra-high field strength and applications in the areas of psychiatric imaging and spinal cord pathologies.Opens internal link in current window[more]

MR Neuroimaging Agents

We develop responsive or smart contrast agents for tracking neuronal activity. These are bioactivated molecules able to detect changes in concentration of ions or molecules relevant for brain function and translate them into changes in MR contrast. These functional markers permit direct visualization of neural activation independent of the state of the vascular system. Opens internal link in current window[more]

Translational Neuroimaging and Neural Control

One research direction is to study the underlying mechanism of neurovascular coupling by identifying the signaling molecules propagating from neuron to glia, and to vessel. The other is to identify the “core switch” underlying the brain arousal and coma states by combining genetic tools with optical imaging and high field fMRI. The goal is to identify candidate molecules from critical brain nuclei, which can contribute to switch brain states. We are expected to translate the knowledge acquired from animal models to novel therapeutic treatment of coma patients. Opens internal link in current window[more]

Space and Body Perception

Our aim is to investigate human perception and behavior using ecologically valid and immersive virtual reality (VR). At the same time we consider the implications of our scientific results for improving design specifications for VR software and technology. VR equipment enables our scientists to provide sensory stimulus in a controlled virtual world and to manipulate or alter sensory input that would not be possible in the real world. Opens internal link in current window[more]

Neuronal Convergence

fMRI is widely used to study the operational organization of the brain. The exact relationship between the measured functional signal and the underlying neural activity, however, is yet unclear. Previous studies (Logothetis et al., 2001; Caesar et al., 2003) have already examined the relationship between large-scale electrical (in particular the local field potentials) and functional activity patterns. However, the large-scale neurochemical context, which is of utmost importance for drug design and development, has so far not been considered. Opens internal link in current window[more]
Last updated: Saturday, 17.06.2017