Contact

Rebekka Bernard

Address: Max-Planck-Ring 11
72076 Tübingen
Room number: 2.B.11
Phone: +49 7071 601 545
Fax: +49 7071 601 652
E-Mail: rebekka.bernard

 

Picture of Bernard, Rebekka

Rebekka Bernard

Position: PhD Student  Unit: Alumni Logothetis Scheffler

My research focuses on:

  • Neurovascular coupling (NVC)
  • Hemodynamic and vascular activity in the brain and, in particular,
  • The physiological causes and mechanisms of the BOLD (blood oxygen level dependent) signal

 

The fMRI BOLD signal is an essential measure for hemodynamic and metabolic activity in the brain and thanks to neurovascular coupling processes, an indirect measure of neuronal activity. But for its accurate interpretation it is important to understand the detailed mechanisms and processes which generate the BOLD signal.

Using simultaneous Intrinsic Optical Imaging (IOI) and ultra-high field fMRI we can measure and monitor hemodynamic activity on a microscopic single vessel level and on a macroscopic level of whole brain areas. By spatially and temporally combining Intrinsic Optical Imaging and ultra-high field fMRI methods we can utilize the good temporal and spatial resolution of IOI and the good and non-invasive accessibility of almost all brain regions with MRI. Combining and comparing the acquired information from single vessels about blood oxy- and deoxygenation, cerebral blood volume (CBV) and blood flow (CBF) and the blood oxygen level dependent (BOLD) signal from whole brain areas enables us to study various components and aspects of brain hemodynamics and from the generated signals.

Detailed project description is coming soon...

Since 07/2017 PhD student at Max Planck Institute for Biological Cybernetics, Tübingen, Germany

 

06/2016 – 06/2017 Research Technician at Max Planck Institute for Biological Cybernetics, Tübingen, Germany

 

10/2012 – 03/2016 M.Sc. Pharmaceutical Sciences, Ludwig-Maximilians-Universität, Munich, Germany

Master’s thesis: Studying neurovascular coupling - effects of hemodynamic changes on neuronal spiking activity (at MPI KYB)

 

10/2008 – 03/2012 B.Sc. Pharmaceutical Sciences, Ludwig-Maximilians-Universität, Munich, Germany

Bachelor‘s thesis: Functional expression analysis of HCN Channel Isoforms in the Mouse Thymus

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Show abstracts

Articles (2):

Zaidi AD, Munk MHJ, Schmidt A, Risueno-Segovia C, Bernard R, Fetz E, Logothetis NK, Bierbaumer N and Sitaram R (October-2015) Simultaneous epidural functional near-infrared spectroscopy and cortical electrophysiology as a tool for studying local neurovascular coupling in primates NeuroImage 120 394–399.
Fenske S, Krause SC, Hassan SIH, Becirovic E, Auer F, Bernard R, Kupatt C, Lange P, Ziegler T, Wotjak CT, Zhang H, Hammelmann V, Paparizos C, Biel M and Wahl-Schott CA (December-2013) Sick Sinus Syndrome in HCN1-Deficient Mice Circulation 128(24) 2585-2594.

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Last updated: Monday, 22.05.2017