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Prof. Dr. Nikos Logothetis

Address: Spemannstr. 38
72076 Tübingen
Room number: 121
Phone: +49 7071 601 651
Fax: +49 7071 601 652
E-Mail: nikos.logothetis

 

Picture of Logothetis, Nikos, Prof. Dr.

Nikos Logothetis

Position: Director  Unit: Logothetis

Research in this laboratory concentrates on the neural mechanisms of perception and object recognition. Although our basic research revolves around vision, a number of independent collaborators are also investigating the relationship between neural activity and perception using other sensory modalities. I firmly believe that such scientific questions require a multimodal methodological approach that integrates information obtained from single units with that derived from mass action potentials as well as from a number of activity-related, surrogate signals such as those monitored during noninvasive experiments. Parallel to our ongoing research, therefore, we are also working to develop methodologies that will permit us to study neural networks in the context of behavioral paradigms. We have already designed and implemented two high-field magnetic resonance imaging systems for functional, anatomical and spectroscopic imaging. The systems are endowed with all the necessary hard- and software to conduct simultaneous imaging and recordings, and they are being used to study the function, connectivity, and neurochemistry of the non-human primate brain. Furthermore, while continuing to exploit traditional neuroimaging in our experiments, we are also investigating the relationship of neural activity to the MR-measurable hemodynamic responses and experimenting with methods that do not rely on hemodynamic responses at all. In the context of the last-named project, a group of synthetic and coordination chemists in my laboratory are attempting to synthesize and evaluate MR-detectable smart probes that change magnetic properties as a function of the concentration of ions and molecules involved in neural signaling. Smart contrast agents, if designed and tested appropriately, promise to revolutionize invasive neuroimaging and would represent a quantum leap forward in signal-to-noise ratio, spatial detail and specificity, while affording unprecedented temporal resolution.
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Nikos K. Logothetis is director of the department “Physiology of Cognitive Processes” at the Max Planck Institute for Biological Cybernetics (MPIK), in Tübingen, Germany. He received a B.S. in mathematics from the University of Athens, a B.S. in biology from the University of Thessaloniki, and his Ph.D. in human neurobiology from the Ludwig-Maximilians University in Munich. In 1985 he moved to the Brain and Cognitive Sciences Department of M.I.T., where he initially worked as a postdoctoral fellow and later as Research Scientist. In 1990 he joined the faculty of the Division of Neuroscience at the Baylor College of Medicine. Seven years later he moved to the Max Planck Institute for Biological Cybernetics to continue his work on the physiological mechanisms underlying visual perception and object recognition.

In addition to visual cognition, his work at MPIC includes auditory perception and multisensory integration, as well as studies of plasticity and neuromodulation. Parallel to this ongoing research, a number of methods have been developed that permit the study of neural networks in the context of behavioral paradigms. Two high-field magnetic resonance imaging systems were designed and implemented for functional, anatomical and spectroscopic imaging. They permit simultaneous imaging and intracortical recordings and are being used to study the function, connectivity, and neurochemistry of the non-human primate brain, as well as the relationship of neural activity to the MR-measurable hemodynamic responses. Last but not least a group of synthetic and coordination chemists at MPIC are attempting to synthesize and evaluate MR-detectable smart probes that change magnetic properties as a function of the concentration of ions and molecules involved in neural signaling.

Since 1992 Nikos K. Logothetis has been Adjunct Professor of Neurobiology at the Salk Institute in San Diego, since 1995 Adjunct Professor of Ophthalmology at the Baylor College of Medicine, Houston, Associate of the Neurosciences Institute, San Diego, Senior Visiting Fellow in University College, London, Adjunct Professor in the Department of Cognitive and Neural Systems and of Cognitive and Neural Systems in the College of Arts and Sciences, both at the Boston University, Massachusetts, a  faculty member at the Victoria University of Manchester (VUM) in England, and Honorary Professor in the Department of Biology at the University of Tübingen.

Nikos K. Logothetis has been or continues to be a member of the Advisory Boards of McGovern Institute, M.I.T.; Brain and Cognitive Sciences, M.I.T., USA; POSIT Science Corporation, San Francisco, USA; IGPS, Freiburg, Germany; Centre of Excellence in Systems Neuroscience of the Academy of Finland, Helsinki, Finland; Brain Imaging Center, Frankfurt am Main, Germany; ICM-ADREC, Paris, France; Brain Center of the Hebrew University, Jerusalem, Israel, and in the Advisory Board of the Brain Research Center of the Weizmann Institute, Jerusalem, Israel.  He served as Receiving Editor for the European Journal of Neuroscience (EJN), Associate Editor for Trends in Cognitive Sciences (TICS), Neuron, Current Biology, Current Opinion Neurobiology, and is a regular reviewer for Nature, Nature Neuroscience, J Neuroscience, PNAS, Cerebral Cortex, Cerebral Blood Flow and Metabolism, Journal of Neurophysiology, Experimental Brain Research, and Vision Research. He is a member of the Society for Neuroscience, European Neuroscience Association, American Association for the Advancement of Science, Association for Research in Vision and Ophthalmology, New York Academy of Sciences, Society for Industrial and Applied Mathematics, American Mathematical Society, International Neuropsychological Society, and Mathematical Association of America.

Nikos K. Logothetis is member of the German Academy of Natural Scientists Leopoldina, of the Rodin Remediation Academy, Honorary Member of the American Academy of Arts and Sciences, and a foreign associate of the National Academy of Sciences of the United States. He is recipient of the DeBakey Award for Excellence in Science, the Golden Brain Award of the Minerva Foundation, the 2003 Louis-Jeantet Prize of Medicine, the 2004 Zülch-Price for Neuroscience, the 2007 IPSEN Prize for Neuronal Plasticity, and the 2008 Alden Spencer Award of Columbia University, New York.

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Posters (520):

Perrodin C Person, Kayser C Person, Logothetis NK Person and Petkov CI Person (July-2012): Visual Influences On Neurons In Voice-Sensitive Cortex, 8th Forum of European Neuroscience (FENS 2012), Barcelona, Spain.
Theodoni P , Panagiotaropoulos TI Person, Kapoor V Person, Logothetis NK Person and Deco G (June-2012): Cortical microcircuit dynamics in visual awareness, AREADNE 2012: Research in Encoding and Decoding of Neural Ensembles, Santorini, Greece.
Papanikolaou A Person, Keliris GA Person, Papageorgiou DT , Shao Y Person, Krapp E , Schiefer U , Logothetis N Person and Smirnakis SM (June-2012): Population Receptive Field Mapping in Human Subjects after Lesions of the Visual Pathway, AREADNE 2012: Research in Encoding and Decoding of Neural Ensembles, Santorini, Greece.
Shao Y Person, Keliris GA Person, Papanikolaou A Person, Fischer DM , Nagy D , Jaegle H , Augath M Person, Logothetis NK Person and Smirnakis SM (June-2012): Population receptive field measurements in the visual cortex of macaque monkeys with and without retinal lesions, AREADNE 2012: Research in Encoding and Decoding of Neural Ensembles, Santorini, Greece.
Hagberg GE Person, Mamedov I Person, Power A Person, Beyerlein M Person, Merkle H Person, Angelovski G Person and Logothetis NK Person (May-9-2012): Diffusion in the extra-cellular space of the rat cerebral cortex probed by MRI and direct infusion of contrast agents, 20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia.
Azadbakht H , Parkes LM , Haroon HA , Augath M Person, Logothetis NK Person, de Crespigny A , D’Arceuil HE and Parker GJM (May-9-2012): Validation of tractography against in vivo tracing in the macaque visual system: effect of distance correction, 20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia.
Mamedov I Person, Engelmann J Person, Hagberg G Person, Eschenko O Person and Logothetis NK Person (May-8-2012): Development of multimodal imaging probes for neuroanatomical connectivity studies in vivo by means of MRI, 20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia.
Placidi M Person, Engelmann J Person, Logothetis NK Person and Angelovski G Person (February-2012): Aryl Phosphonate-appended macrocyclic lanthanide complexes for application in bimodal imaging, 2011 World Molecular Imaging Congress (WMIC 2011), San Diego, CA, USA, Molecular Imaging and Biology, 14(1 Supplement) S92.
Besserve M Person, Panagiotaropoulos T Person, Crocker B Person, Kapoor V Person, Tolias A Person, Panzeri S Person and Logothetis NK Person (February-2012): Identifying endogenous rhythmic spatio-temporal patterns in micro-electrode array recordings, 9th Annual Computational and Systems Neuroscience Meeting (Cosyne 2012), Salt Lake City, UT, USA.
Oukhatar F , Angelovski G Person, Logothetis NK Person and Toth E (February-2012): MRI Responsive Contrast Agents: Towards Sensing and Imaging of Neurotransmitters, 2011 World Molecular Imaging Congress (WMIC 2011), San Diego, CA, USA, Molecular Imaging and Biology, 14(1 Supplement) S58.
Gleiss S Person, Lippert MT Person, Takagaki K , Logothetis NK Person, Ohl FW and Kayser C Person (February-2012): Multisensory integration in the rat: behavioral benefits and neural correlates in parietal cortex, 9th Annual Computational and Systems Neuroscience Meeting (Cosyne 2012), Salt Lake City, UT, USA.
Kayser C Person, Logothetis NK Person and Panzeri S Person (November-2011): A computational proof of concept for how slow rhythms could serve as internal reference frames for decoding firing patterns in sensory cortices, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Forro T Person, Logothetis NK Person and Evrard HC Person (November-2011): Distribution of a large spindle-shaped neuron in the anterior agranular insula in the macaque monkey, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Zaldivar D Person, Li J Person, von Pföstl V Person, Zhang X Person, Logothetis NK Person and Rauch A Person (November-2011): Dopaminergic modulation of the early visual system of non-human primates and its underlying neuronal and hemodynamic changes, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Evrard HC Person, Zilles K , Sherwood CC and Logothetis NK Person (November-2011): Large spindle-shaped neurons in the anterior insula in lesser apes and monkeys, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Crocker B Person, Kapoor V Person, Panzeri S Person, Logothetis NK Person and Panagiotaropoulos T Person (November-2011): Low frequency local field potentials in the inferior convexity of the macaque prefrontal cortex convey visual information during anesthesia, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Panzeri S Person, Mazzoni A , Kayser C Person, Murayama Y Person, Quian Quiroga R , Martinez J and Logothetis NK Person (November-2011): Neurons in primary visual cortex encode naturalistic visual information using multiple temporal scales, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Li J Person, Zaldivar D Person, von Pföstl V Person, Serr N Person, Zhang X Person, Logothetis NK Person and Rauch A Person (November-2011): Nicotinic modulation of the early visual system and its underlying neuronal and metabolic changes, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Magri C Person, Mazzoni A , Logothetis NK Person and Panzeri S Person (November-2011): Optimal Band Separation of Local Field Potentials, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Papanikolaou A Person, Keliris GA Person, Shao Y Person, Krapp E , Papageorgiou E , Schiefer U , Logothetis NK Person and Smirnakis SM (November-2011): Population receptive field mapping in human subjects with lesions of the visual cortex, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Shao Y Person, Keliris GA Person, Papanikolaou A Person, Augath M Person, Logothetis NK Person and Smirnakis SM (November-2011): Population receptive field measurements in visual cortex of macaque monkeys, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Panagiotaropoulos T Person, Besserve M Person, Crocker B Person, Kapoor V Person, Tolias AS Person, Panzeri S Person and Logothetis NK Person (November-2011): Spatiotemporal mapping of rhythmic activity in the inferior convexity of the macaque prefrontal cortex, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Brasselet R Person, Panzeri S Person, Logothetis NK Person and Kayser C Person (November-2011): Stimulus encoding in temporal firing patterns relative to population-derived stimulus onset times, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Barbieri F , Mazzoni A , Logothetis NK Person, Panzeri S Person and Brunel N (November-2011): The dynamics of local field potential in monkey primary visual cortex under naturalistic stimulation is well captured by a model network of excitatory and inhibitory integrate-and-fire neurons, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Schridde U Person, Magri C Person, Panzeri S Person and Logothetis NK Person (November-2011): Amplitude and timing of BOLD fMRI are related to specific LFP frequency bands, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
van Keulen S Person, Logothetis NK Person and Eschenko O Person (October-2011): Differential noradrenergic modulation of the rat somatosensory and prefrontal cortex, 12th Conference of Junior Neuroscientists of Tübingen (NeNA 2011), Heiligkreuztal, Germany.
Ng BSW Person, Logothetis NK Person and Kayser C Person (October-2011): Neural correlates of auditory stimulus selectivity encoded by the precise temporal structure of EEG oscillations, Computational Neuroscience & Neurotechnology Bernstein Conference & Neurex Annual Meeting (BC11), Freiburg, Germany, Frontiers in Computational Neuroscience, Conference Abstract: BC11 223-224.
Bahmani H Person, Logothetis NK Person and Keliris GA Person (October-2011): Neural correlates of binocular rivalry in parietal cortex, Computational Neuroscience & Neurotechnology Bernstein Conference & Neurex Annual Meeting (BC11), Freiburg, Germany, Frontiers in Computational Neuroscience, Conference Abstract: BC11 123-125.
Bahmani H Person, Logothetis NK Person and Keliris GA Person (October-2011): Neural Correlates of Binocular Rivalry in Parietal Cortex, 12th Conference of Junior Neuroscientists of Tübingen (NeNA 2011), Heiligkreuztal, Germany.
Brasselet R Person, Panzeri S Person, Logothetis NK Person and Kayser C Person (October-2011): Neurons with unselective rapid responses as reference for relative temporal coding in primate auditory cortex, Computational Neuroscience & Neurotechnology Bernstein Conference & Neurex Annual Meeting (BC11), Freiburg, Germany, Frontiers in Computational Neuroscience, Conference Abstract: BC11 77-79.
Papanikolaou A Person, Keliris G Person, Shao Y Person, Krapp E , Schiefer U , Logothetis NK Person and Smirnakis S (October-2011): Population receptive field mapping in human subjects with visual cortical lesions, 12th Conference of Junior Neuroscientists of Tübingen (NeNA 2011), Heiligkreuztal, Germany.
Lange Canhos L Person, Marzo A Person, Logothetis NK Person and Eschenko O Person (October-2011): The role of noradrenergic modulation for auditory discrimination learning in rats: development of a behavioral paradigm, 12th Conference of Junior Neuroscientists of Tübingen (NeNA 2011), Heiligkreuztal, Germany.
Pérez A , Iturria-Medina Y , Morris D , Canales-Rodríguez E , Haroon H , García l , Augath M Person, Logothetis NK Person, Melie-Garcia L and Parker G (September-2011): Brain hemispheric structural efficiency and interconnectivity rightward asymmetry, XI International Conference on Cognitive Neuroscience (ICON XI), Palma, Mallorca, Spain, Frontiers in Human Neuroscience, Conference Abstract: XI International Conference on Cognitive Neuroscience (ICON XI).
van Keulen S Person, Logothetis NK Person and Eschenko O Person (September-2011): Differential noradrenergic modulation in the rat somatosensory and prefrontal cortex, Networks! 2011: 2nd German Neurophysiology PhD Meeting, Tübingen, Germany.
van Keulen S Person, Logothetis NK Person and Eschenko O Person (September-2011): Differential noradrenergic modulation in the rat somatosensory and prefrontal cortex, 43rd Meeting of the European Brain and Behavior Society (EBBS 2011), Sevilla, Spain.
Magri C Person, Schridde U Person, Panzeri S Person, Murayama Y Person and Logothetis NK Person (July-2011): Different LFP frequency bands convey complementary information about the BOLD signal, Twentieth Annual Computational Neuroscience Meeting (CNS*2011), Stockholm, Sweden, BMC Neuroscience, 12(Suppl 1) P204.
Siadatnejad S , Panzeri S Person, Kayser C Person, Logothetis NK Person and Montemurro MA (July-2011): Does the information in the phase of low frequency LFP reflect the low frequency envelope of local spike rates?, Twentieth Annual Computational Neuroscience Meeting (CNS*2011), Stockholm, Sweden, BMC Neuroscience, 12(Suppl 1) P227.
Mazzoni A , Kayser C Person, Murayama Y Person, Martinez J , Quiroga RQ , Logothetis NK Person and Panzeri S Person (July-2011): Local field potential phase and spike timing convey information about different visual features in primary visual cortex, Twentieth Annual Computational Neuroscience Meeting (CNS*2011), Stockholm, Sweden, BMC Neuroscience, 12(Suppl 1) P248.
Valverde Salzmann MF Person, Logothetis NK Person and Pohmann R Person (May-10-2011): High-Resolution Imaging of Vessels in the Isolated Rat Brain, 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montréal, Canada.
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Goense J Person and Logothetis NK Person (May-9-2011): Differences in Neurovascular Coupling in Areas with Positive & Negative BOLD Signal, 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montréal, Canada.
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Bohraus Y Person, Logothetis NK Person and Goense J Person (May-9-2011): High resolution CMRO2 in visual cortex of macaca mulatta, 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montréal, Canada.
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Hagberg GE Person, Balla D Person, Wiesner HM Person and Logothetis NK Person (May-9-2011): Small-Scale Phase & Magnitude Fluctuations in fMRI Time Series, 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montréal, Canada.
Perrodin C Person, Kayser C Person, Logothetis NK Person and Petkov CI Person (March-2011): Electrophysiological characterization of an fMRI-identified voicepreferring region, 9th Göttingen Meeting of the German Neuroscience Society, 33rd Göttingen Neurobiology Conference, Göttingen, Germany.
Kayser C Person, Mazzoni A , Logothetis NK Person and Panzeri S Person (March-2011): The time scales of neural coding in auditory and visual cortices of the primate, 9th Göttingen Meeting of the German Neuroscience Society, 33rd Göttingen Neurobiology Conference, Göttingen, Germany.
Liebe S Person, Hoerzer G , Logothetis NK Person and Rainer G Person (February-2011): Long range coupling in theta between V4 and prefrontal cortex predicts visual memory performance, Computational and Systems Neuroscience Meeting (COSYNE 2011), Salt Lake City, UT, USA.
Sigala Alanis GR Person, Schultz J Person, Logothetis NK Person and Rainer G Person (November-2010): "Own-species" bias in the categorical representation of a human/monkey continuum in the human and non-human primate temporal lobe, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Rancz EA , Canals SG Person, Logothetis NK Person, Brichta AM and Margrie TW (November-2010): A cortical map of vestibular representation in the rodent brain revealed by functional imaging and electrophysiology, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Keliris GA Person, Shao Y Person, Papanikolaou A Person, Peng X , Logothetis NK Person and Smirnakis SM Person (November-2010): Assessing the spatio-temporal dynamics of visual receptive fields by fMRI, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Li J Person, von Pföstl V Person, Zaldivar D Person, Zhang X Person, Logothetis NK Person and Rauch A Person (November-2010): Comparing concentration levels of multiple neurochemically active compounds in blood and brain tissue of non-human primates by using dual microdialysis sampling and capillary hydrophilic interaction chromatography-mass s pectrometry, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Schridde U Person, Whittingstall K Person, Murayama Y Person and Logothetis NK Person (November-2010): Cross-frequency coupling of neural signals within and between early visual areas V1 and V2, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
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Last updated: Tuesday, 18.11.2014