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Prof. Dr. Nikos Logothetis

Address: Spemannstr. 38
72076 Tübingen
Room number: 121
Phone: +49 7071 601 651
Fax: +49 7071 601 652
E-Mail: nikos.logothetis

 

Picture of Logothetis, Nikos, Prof. Dr.

Nikos Logothetis

Position: Director  Unit: Logothetis

Research in this laboratory concentrates on the neural mechanisms of perception and object recognition. Although our basic research revolves around vision, a number of independent collaborators are also investigating the relationship between neural activity and perception using other sensory modalities. I firmly believe that such scientific questions require a multimodal methodological approach that integrates information obtained from single units with that derived from mass action potentials as well as from a number of activity-related, surrogate signals such as those monitored during noninvasive experiments. Parallel to our ongoing research, therefore, we are also working to develop methodologies that will permit us to study neural networks in the context of behavioral paradigms. We have already designed and implemented two high-field magnetic resonance imaging systems for functional, anatomical and spectroscopic imaging. The systems are endowed with all the necessary hard- and software to conduct simultaneous imaging and recordings, and they are being used to study the function, connectivity, and neurochemistry of the non-human primate brain. Furthermore, while continuing to exploit traditional neuroimaging in our experiments, we are also investigating the relationship of neural activity to the MR-measurable hemodynamic responses and experimenting with methods that do not rely on hemodynamic responses at all. In the context of the last-named project, a group of synthetic and coordination chemists in my laboratory are attempting to synthesize and evaluate MR-detectable smart probes that change magnetic properties as a function of the concentration of ions and molecules involved in neural signaling. Smart contrast agents, if designed and tested appropriately, promise to revolutionize invasive neuroimaging and would represent a quantum leap forward in signal-to-noise ratio, spatial detail and specificity, while affording unprecedented temporal resolution.
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Nikos K. Logothetis is director of the department “Physiology of Cognitive Processes” at the Max Planck Institute for Biological Cybernetics (MPIK), in Tübingen, Germany. He received a B.S. in mathematics from the University of Athens, a B.S. in biology from the University of Thessaloniki, and his Ph.D. in human neurobiology from the Ludwig-Maximilians University in Munich. In 1985 he moved to the Brain and Cognitive Sciences Department of M.I.T., where he initially worked as a postdoctoral fellow and later as Research Scientist. In 1990 he joined the faculty of the Division of Neuroscience at the Baylor College of Medicine. Seven years later he moved to the Max Planck Institute for Biological Cybernetics to continue his work on the physiological mechanisms underlying visual perception and object recognition.

In addition to visual cognition, his work at MPIC includes auditory perception and multisensory integration, as well as studies of plasticity and neuromodulation. Parallel to this ongoing research, a number of methods have been developed that permit the study of neural networks in the context of behavioral paradigms. Two high-field magnetic resonance imaging systems were designed and implemented for functional, anatomical and spectroscopic imaging. They permit simultaneous imaging and intracortical recordings and are being used to study the function, connectivity, and neurochemistry of the non-human primate brain, as well as the relationship of neural activity to the MR-measurable hemodynamic responses. Last but not least a group of synthetic and coordination chemists at MPIC are attempting to synthesize and evaluate MR-detectable smart probes that change magnetic properties as a function of the concentration of ions and molecules involved in neural signaling.

Since 1992 Nikos K. Logothetis has been Adjunct Professor of Neurobiology at the Salk Institute in San Diego, since 1995 Adjunct Professor of Ophthalmology at the Baylor College of Medicine, Houston, Associate of the Neurosciences Institute, San Diego, Senior Visiting Fellow in University College, London, Adjunct Professor in the Department of Cognitive and Neural Systems and of Cognitive and Neural Systems in the College of Arts and Sciences, both at the Boston University, Massachusetts, a  faculty member at the Victoria University of Manchester (VUM) in England, and Honorary Professor in the Department of Biology at the University of Tübingen.

Nikos K. Logothetis has been or continues to be a member of the Advisory Boards of McGovern Institute, M.I.T.; Brain and Cognitive Sciences, M.I.T., USA; POSIT Science Corporation, San Francisco, USA; IGPS, Freiburg, Germany; Centre of Excellence in Systems Neuroscience of the Academy of Finland, Helsinki, Finland; Brain Imaging Center, Frankfurt am Main, Germany; ICM-ADREC, Paris, France; Brain Center of the Hebrew University, Jerusalem, Israel, and in the Advisory Board of the Brain Research Center of the Weizmann Institute, Jerusalem, Israel.  He served as Receiving Editor for the European Journal of Neuroscience (EJN), Associate Editor for Trends in Cognitive Sciences (TICS), Neuron, Current Biology, Current Opinion Neurobiology, and is a regular reviewer for Nature, Nature Neuroscience, J Neuroscience, PNAS, Cerebral Cortex, Cerebral Blood Flow and Metabolism, Journal of Neurophysiology, Experimental Brain Research, and Vision Research. He is a member of the Society for Neuroscience, European Neuroscience Association, American Association for the Advancement of Science, Association for Research in Vision and Ophthalmology, New York Academy of Sciences, Society for Industrial and Applied Mathematics, American Mathematical Society, International Neuropsychological Society, and Mathematical Association of America.

Nikos K. Logothetis is member of the German Academy of Natural Scientists Leopoldina, of the Rodin Remediation Academy, Honorary Member of the American Academy of Arts and Sciences, and a foreign associate of the National Academy of Sciences of the United States. He is recipient of the DeBakey Award for Excellence in Science, the Golden Brain Award of the Minerva Foundation, the 2003 Louis-Jeantet Prize of Medicine, the 2004 Zülch-Price for Neuroscience, the 2007 IPSEN Prize for Neuronal Plasticity, and the 2008 Alden Spencer Award of Columbia University, New York.

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Posters (514):

Panagiotaropoulos T Person, Besserve M Person, Crocker B Person, Kapoor V Person, Tolias AS Person, Panzeri S Person and Logothetis NK Person (November-2011): Spatiotemporal mapping of rhythmic activity in the inferior convexity of the macaque prefrontal cortex, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Brasselet R Person, Panzeri S Person, Logothetis NK Person and Kayser C Person (November-2011): Stimulus encoding in temporal firing patterns relative to population-derived stimulus onset times, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Barbieri F , Mazzoni A , Logothetis NK Person, Panzeri S Person and Brunel N (November-2011): The dynamics of local field potential in monkey primary visual cortex under naturalistic stimulation is well captured by a model network of excitatory and inhibitory integrate-and-fire neurons, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
Schridde U Person, Magri C Person, Panzeri S Person and Logothetis NK Person (November-2011): Amplitude and timing of BOLD fMRI are related to specific LFP frequency bands, 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, DC, USA.
van Keulen S Person, Logothetis NK Person and Eschenko O Person (October-2011): Differential noradrenergic modulation of the rat somatosensory and prefrontal cortex, 12th Conference of Junior Neuroscientists of Tübingen (NeNA 2011), Heiligkreuztal, Germany.
Ng BSW Person, Logothetis NK Person and Kayser C Person (October-2011): Neural correlates of auditory stimulus selectivity encoded by the precise temporal structure of EEG oscillations, Computational Neuroscience & Neurotechnology Bernstein Conference & Neurex Annual Meeting (BC11), Freiburg, Germany, Frontiers in Computational Neuroscience, Conference Abstract: BC11 223-224.
Bahmani H Person, Logothetis NK Person and Keliris GA Person (October-2011): Neural correlates of binocular rivalry in parietal cortex, Computational Neuroscience & Neurotechnology Bernstein Conference & Neurex Annual Meeting (BC11), Freiburg, Germany, Frontiers in Computational Neuroscience, Conference Abstract: BC11 123-125.
Bahmani H Person, Logothetis NK Person and Keliris GA Person (October-2011): Neural Correlates of Binocular Rivalry in Parietal Cortex, 12th Conference of Junior Neuroscientists of Tübingen (NeNA 2011), Heiligkreuztal, Germany.
Brasselet R Person, Panzeri S Person, Logothetis NK Person and Kayser C Person (October-2011): Neurons with unselective rapid responses as reference for relative temporal coding in primate auditory cortex, Computational Neuroscience & Neurotechnology Bernstein Conference & Neurex Annual Meeting (BC11), Freiburg, Germany, Frontiers in Computational Neuroscience, Conference Abstract: BC11 77-79.
Papanikolaou A Person, Keliris G Person, Shao Y Person, Krapp E , Schiefer U , Logothetis NK Person and Smirnakis S (October-2011): Population receptive field mapping in human subjects with visual cortical lesions, 12th Conference of Junior Neuroscientists of Tübingen (NeNA 2011), Heiligkreuztal, Germany.
Lange Canhos L Person, Marzo A Person, Logothetis NK Person and Eschenko O Person (October-2011): The role of noradrenergic modulation for auditory discrimination learning in rats: development of a behavioral paradigm, 12th Conference of Junior Neuroscientists of Tübingen (NeNA 2011), Heiligkreuztal, Germany.
Pérez A , Iturria-Medina Y , Morris D , Canales-Rodríguez E , Haroon H , García l , Augath M Person, Logothetis NK Person, Melie-Garcia L and Parker G (September-2011): Brain hemispheric structural efficiency and interconnectivity rightward asymmetry, XI International Conference on Cognitive Neuroscience (ICON XI), Palma, Mallorca, Spain, Frontiers in Human Neuroscience, Conference Abstract: XI International Conference on Cognitive Neuroscience (ICON XI).
van Keulen S Person, Logothetis NK Person and Eschenko O Person (September-2011): Differential noradrenergic modulation in the rat somatosensory and prefrontal cortex, Networks! 2011: 2nd German Neurophysiology PhD Meeting, Tübingen, Germany.
van Keulen S Person, Logothetis NK Person and Eschenko O Person (September-2011): Differential noradrenergic modulation in the rat somatosensory and prefrontal cortex, 43rd Meeting of the European Brain and Behavior Society (EBBS 2011), Sevilla, Spain.
Magri C Person, Schridde U Person, Panzeri S Person, Murayama Y Person and Logothetis NK Person (July-2011): Different LFP frequency bands convey complementary information about the BOLD signal, Twentieth Annual Computational Neuroscience Meeting (CNS*2011), Stockholm, Sweden, BMC Neuroscience, 12(Suppl 1) P204.
Siadatnejad S , Panzeri S Person, Kayser C Person, Logothetis NK Person and Montemurro MA (July-2011): Does the information in the phase of low frequency LFP reflect the low frequency envelope of local spike rates?, Twentieth Annual Computational Neuroscience Meeting (CNS*2011), Stockholm, Sweden, BMC Neuroscience, 12(Suppl 1) P227.
Mazzoni A , Kayser C Person, Murayama Y Person, Martinez J , Quiroga RQ , Logothetis NK Person and Panzeri S Person (July-2011): Local field potential phase and spike timing convey information about different visual features in primary visual cortex, Twentieth Annual Computational Neuroscience Meeting (CNS*2011), Stockholm, Sweden, BMC Neuroscience, 12(Suppl 1) P248.
Goense J Person and Logothetis NK Person (May-9-2011): Differences in neurovascular coupling in areas with positive and negative BOLD signal, 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montréal, Canada.
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Bohraus Y Person, Logothetis NK Person and Goense J Person (May-9-2011): High resolution CMRO2 in visual cortex of macaca mulatta, 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montréal, Canada.
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Hagberg GE Person, Balla D Person, Wiesner HM Person and Logothetis NK Person (May-9-2011): Small-scale Phase and Magnitude fluctuations in fMRI time series, 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montréal, Canada.
Valverde Salzmann MF Person, Logothetis NK Person and Pohmann R Person (May-2011): High-Resolution Imaging of Vessels in the Isolated Rat Brain, 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montréal, Canada.
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Perrodin C Person, Kayser C Person, Logothetis NK Person and Petkov CI Person (March-2011): Electrophysiological characterization of an fMRI-identified voicepreferring region, 9th Göttingen Meeting of the German Neuroscience Society, 33rd Göttingen Neurobiology Conference, Göttingen, Germany.
Kayser C Person, Mazzoni A , Logothetis NK Person and Panzeri S Person (March-2011): The time scales of neural coding in auditory and visual cortices of the primate, 9th Göttingen Meeting of the German Neuroscience Society, 33rd Göttingen Neurobiology Conference, Göttingen, Germany.
Liebe S Person, Hoerzer G , Logothetis NK Person and Rainer G Person (February-2011): Long range coupling in theta between V4 and prefrontal cortex predicts visual memory performance, Computational and Systems Neuroscience Meeting (COSYNE 2011), Salt Lake City, UT, USA.
Sigala Alanis GR Person, Schultz J Person, Logothetis NK Person and Rainer G Person (November-2010): "Own-species" bias in the categorical representation of a human/monkey continuum in the human and non-human primate temporal lobe, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Rancz EA , Canals SG Person, Logothetis NK Person, Brichta AM and Margrie TW (November-2010): A cortical map of vestibular representation in the rodent brain revealed by functional imaging and electrophysiology, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Keliris GA Person, Shao Y Person, Papanikolaou A Person, Peng X , Logothetis NK Person and Smirnakis SM Person (November-2010): Assessing the spatio-temporal dynamics of visual receptive fields by fMRI, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Li J Person, von Pföstl V Person, Zaldivar D Person, Zhang X Person, Logothetis NK Person and Rauch A Person (November-2010): Comparing concentration levels of multiple neurochemically active compounds in blood and brain tissue of non-human primates by using dual microdialysis sampling and capillary hydrophilic interaction chromatography-mass s pectrometry, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Schridde U Person, Whittingstall K Person, Murayama Y Person and Logothetis NK Person (November-2010): Cross-frequency coupling of neural signals within and between early visual areas V1 and V2, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Ecker AS Person, Berens P Person, Keliris GA Person, Bethge M Person, Logothetis NK Person and Tolias AS Person (November-2010): Decorrelated neuronal firing in cortical microcircuits, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
von Pföstl V Person, Li J Person, Zaldivar D Person, Goense J Person, Zhang X Person, Logothetis NK Person and Rauch A Person (November-2010): Effects of lactate on primary visual cortex of non-human primates investigated by pharmaco mri and neurochemical analysis, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Fischer E Person, Bülthoff HH Person, Logothetis NK Person and Bartels A Person (November-2010): Evidence for predictive coding in early visual cortex in context of self-induced visual motion, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Besserve M Person, Murayama Y Person, Schölkopf B Person, Logothetis NK Person and Panzeri S Person (November-2010): High frequency phase-spike synchronization of extracellular signals modulates causal interactions in monkey primary visual cortex, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Bartlett AM , Logothetis NK Person and Hoffman KL Person (November-2010): Interplay of visually-evoked and saccade-evoked activity in the primate superior temporal lobe, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Kayser C Person, Logothetis NK Person and Panzeri S Person (November-2010): Population coding in auditory cortex - time scales and intrinsic reference frames, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Shao Y Person, Keliris GA Person, Papanikolaou A Person, Fischer DM , Nagy D , Jägle H , Seeliger MW , Augath M Person, Logothetis NK Person and Smirnakis SM Person (November-2010): Population receptive field mapping in a macaque monkey with macular degeneration, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Papanikolaou A Person, Keliris GA Person, Peng X , Shao Y Person, Krapp E , Papageorgiou E , Schiefer U , Logothetis NK Person and Smirnakis SM Person (November-2010): Population receptive field mapping in human subjects with visual cortical lesions, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Musall S Person, Logothetis NK Person and Whittingstall KS Person (November-2010): Predicting surface EEG power through fluctuations in intracortical signals during different behavioral and pharmacological conditions, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Ku S-P Person, Tolias AS Person, Logothetis NK Person and Goense J Person (November-2010): The face selective activity in ventral temporal lobe in macaques, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Remedios R Person, Logothetis NK Person and Kayser C Person (November-2010): Vocal and non-vocal acoustic communication systems in the macaque brain, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Liebe S Person, Hoerzer G , Logothetis NK Person and Rainer G Person (October-2010): Oscillatory neuronal synchronization between prefrontal and extrastriate visual cortex during visual memory, 40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010), San Diego, CA, USA.
Mishra A Person, Parker D and Logothetis NK Person (September-2010): PyroEGTA-Derived Metal Ion Responsive Probes for MRI, 2010 World Molecular Imaging Congress (WMIC), Kyoto, Japan.
Angelovski G Person, Mamdeov I Person, Engelmann J Person, Gottschalk S Person, Balla DZ Person, Pohmann R Person and Logothetis NK Person (September-2010): The Use of Gadolinium-based Contrast Agents for Molecular and Cellular MRI: Quantitative Considerations, 2010 World Molecular Imaging Congress (WMIC), Kyoto, Japan.
Mamedov I Person, Parac-Vogt T , Logothetis NK Person and Angelovski G Person (September-2010): Title Dinuclear Heterometallic Lanthanide Complexes Exhibiting MRI and Luminescence Response, 2010 World Molecular Imaging Congress (WMIC), Kyoto, Japan.
Fischer E Person, Bülthoff HH Person, Logothetis NK Person and Bartels A Person (August-2010): Functional characteristics of a motion responsive region in the posterior cingulate cortex compared to V5/MT and MST, 33rd European Conference on Visual Perception, Lausanne, Switzerland, Perception, 39(ECVP Abstract Supplement) 95.
Neves RM Person, Eschenko O Person, Evrard H Person, Beyerlein M Person and Logothetis NK Person (July-2010): Mapping noradrenergic projections from locus coeruleus using classical fluorescent tracer and MRI-visible contrast agent, 7th Forum of European Neuroscience (FENS 2010), Amsterdam, Netherlands.
Pietrajtis K Person, Sara SJ , Logothetis NK Person and Eschenko O Person (July-2010): Spike timing among neurons recorded simultaneously in locus coeruleus, ventral tegmental area and frontal cortex during somatosensory stimulation: LC leads!, 7th Forum of European Neuroscience (FENS 2010), Amsterdam, Netherlands.
Zaretskaya N Person, Thielscher A Person, Logothetis NK Person and Bartels A Person (June-2010): Binocular Rivalry: a Causal role of the Parietal Cortex in Perceptual Selection, 16th Annual Meeting of the Organisation for Human Brain Mapping (HBM 2010), Barcelona, Spain.
Sigala R Person, Schultz J Person, Logothetis NK Person and Rainer G Person (June-2010): Categorical Representation of a Human/Monkey Face Continum in the Human and Non-Human Primate Temporal Lobe, AREADNE 2010: Research in Encoding And Decoding of Neural Ensembles, Santorini, Greece.
Aggelopoulos NC Person, Melano T Person, Logothetis NK Person and Rainer G Person (June-2010): Cholinergic Dependence of a Cognitive Task, AREADNE 2010: Research in Encoding And Decoding of Neural Ensembles, Santorini, Greece.
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Last updated: Tuesday, 18.11.2014