Contact

Prof. Dr. Nikos Logothetis

Address: Spemannstr. 38
72076 Tübingen
Room number: 121
Phone: +49 7071 601 651
Fax: +49 7071 601 652
E-Mail: nikos.logothetis

 

Picture of Logothetis, Nikos, Prof. Dr.

Nikos Logothetis

Position: Director  Unit: Logothetis

Research in this laboratory concentrates on the neural mechanisms of perception and object recognition. Although our basic research revolves around vision, a number of independent collaborators are also investigating the relationship between neural activity and perception using other sensory modalities. I firmly believe that such scientific questions require a multimodal methodological approach that integrates information obtained from single units with that derived from mass action potentials as well as from a number of activity-related, surrogate signals such as those monitored during noninvasive experiments. Parallel to our ongoing research, therefore, we are also working to develop methodologies that will permit us to study neural networks in the context of behavioral paradigms. We have already designed and implemented two high-field magnetic resonance imaging systems for functional, anatomical and spectroscopic imaging. The systems are endowed with all the necessary hard- and software to conduct simultaneous imaging and recordings, and they are being used to study the function, connectivity, and neurochemistry of the non-human primate brain. Furthermore, while continuing to exploit traditional neuroimaging in our experiments, we are also investigating the relationship of neural activity to the MR-measurable hemodynamic responses and experimenting with methods that do not rely on hemodynamic responses at all. In the context of the last-named project, a group of synthetic and coordination chemists in my laboratory are attempting to synthesize and evaluate MR-detectable smart probes that change magnetic properties as a function of the concentration of ions and molecules involved in neural signaling. Smart contrast agents, if designed and tested appropriately, promise to revolutionize invasive neuroimaging and would represent a quantum leap forward in signal-to-noise ratio, spatial detail and specificity, while affording unprecedented temporal resolution.
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Nikos K. Logothetis is director of the department “Physiology of Cognitive Processes” at the Max Planck Institute for Biological Cybernetics (MPIK), in Tübingen, Germany. He received a B.S. in mathematics from the University of Athens, a B.S. in biology from the University of Thessaloniki, and his Ph.D. in human neurobiology from the Ludwig-Maximilians University in Munich. In 1985 he moved to the Brain and Cognitive Sciences Department of M.I.T., where he initially worked as a postdoctoral fellow and later as Research Scientist. In 1990 he joined the faculty of the Division of Neuroscience at the Baylor College of Medicine. Seven years later he moved to the Max Planck Institute for Biological Cybernetics to continue his work on the physiological mechanisms underlying visual perception and object recognition.

In addition to visual cognition, his work at MPIC includes auditory perception and multisensory integration, as well as studies of plasticity and neuromodulation. Parallel to this ongoing research, a number of methods have been developed that permit the study of neural networks in the context of behavioral paradigms. Two high-field magnetic resonance imaging systems were designed and implemented for functional, anatomical and spectroscopic imaging. They permit simultaneous imaging and intracortical recordings and are being used to study the function, connectivity, and neurochemistry of the non-human primate brain, as well as the relationship of neural activity to the MR-measurable hemodynamic responses. Last but not least a group of synthetic and coordination chemists at MPIC are attempting to synthesize and evaluate MR-detectable smart probes that change magnetic properties as a function of the concentration of ions and molecules involved in neural signaling.

Since 1992 Nikos K. Logothetis has been Adjunct Professor of Neurobiology at the Salk Institute in San Diego, since 1995 Adjunct Professor of Ophthalmology at the Baylor College of Medicine, Houston, Associate of the Neurosciences Institute, San Diego, Senior Visiting Fellow in University College, London, Adjunct Professor in the Department of Cognitive and Neural Systems and of Cognitive and Neural Systems in the College of Arts and Sciences, both at the Boston University, Massachusetts, a  faculty member at the Victoria University of Manchester (VUM) in England, and Honorary Professor in the Department of Biology at the University of Tübingen.

Nikos K. Logothetis has been or continues to be a member of the Advisory Boards of McGovern Institute, M.I.T.; Brain and Cognitive Sciences, M.I.T., USA; POSIT Science Corporation, San Francisco, USA; IGPS, Freiburg, Germany; Centre of Excellence in Systems Neuroscience of the Academy of Finland, Helsinki, Finland; Brain Imaging Center, Frankfurt am Main, Germany; ICM-ADREC, Paris, France; Brain Center of the Hebrew University, Jerusalem, Israel, and in the Advisory Board of the Brain Research Center of the Weizmann Institute, Jerusalem, Israel.  He served as Receiving Editor for the European Journal of Neuroscience (EJN), Associate Editor for Trends in Cognitive Sciences (TICS), Neuron, Current Biology, Current Opinion Neurobiology, and is a regular reviewer for Nature, Nature Neuroscience, J Neuroscience, PNAS, Cerebral Cortex, Cerebral Blood Flow and Metabolism, Journal of Neurophysiology, Experimental Brain Research, and Vision Research. He is a member of the Society for Neuroscience, European Neuroscience Association, American Association for the Advancement of Science, Association for Research in Vision and Ophthalmology, New York Academy of Sciences, Society for Industrial and Applied Mathematics, American Mathematical Society, International Neuropsychological Society, and Mathematical Association of America.

Nikos K. Logothetis is member of the German Academy of Natural Scientists Leopoldina, of the Rodin Remediation Academy, Honorary Member of the American Academy of Arts and Sciences, and a foreign associate of the National Academy of Sciences of the United States. He is recipient of the DeBakey Award for Excellence in Science, the Golden Brain Award of the Minerva Foundation, the 2003 Louis-Jeantet Prize of Medicine, the 2004 Zülch-Price for Neuroscience, the 2007 IPSEN Prize for Neuronal Plasticity, and the 2008 Alden Spencer Award of Columbia University, New York.

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Articles (333):

Logothetis NK (June-2000) Object recognition: Holistic representations in the monkey brain Spatial Vision 13(2-3) 165-178.
Logothetis NK (May-2000) Can current fMRI techniques reveal the micro-architecture of cortex? Nature Neuroscience 3(5) 413.
Gauthier I and Logothetis NK (February-2000) Is face recognition not so unique, after all? Cognitive Neuropsychology 17(1-3) 125-142.
Sheinberg DL and Logothetis NK (February-2000) Noticing Familiar Objects in Real World Scenes: The Role of Temporal Cortical Neurons in Natural Vision Journal of Neuroscience 21(4) 1340-1350.
Logothetis NK (January-2000) Das Sehen - ein Fenster zum Bewusstsein Spektrum der Wissenschaft 2000(1) 36-43.
Logothetis NK (November-1999) Vision: A window on consciousness Scientific American 281(5) 68-75.
Leopold DA and Logothetis NK (July-1999) Multistable phenomena: changing views in perception Trends In Cognitive Sciences 3(7) 254-264.
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Logothetis NK, Guggenberger H, Peled S and Pauls J (June-1999) Functional imaging of the monkey brain Nature Neuroscience 2(6) 555-562.
Leopold DA and Logothetis NK (November-1998) Microsaccades differentially modulate neural activity in the striate and extrastriate visual cortex Experimental Brain Research 123(3) 341-345.
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Logothetis NK (November-1998) Single units and conscious vision Philosophical Transactions of the Royal Society of London B 353(1377) 1801-1818.
Logothetis NK (October-1998) See and grasp Nature 395(6701) 444-445.
Logothetis NK (August-1998) Object vision and visual awareness Current Opinion in Neurobiology 8(4) 536-544.
Logothetis NK, Leopold DA and Sheinberg DL (July-1997) Neural mechanisms of perceptual organization Cognitive Studies 4(3) 99-110.
Sheinberg DL and Logothetis NK (April-1997) The role of temporal cortical areas in perceptual organization. Proceedings of the National Academy of Sciences of the United States of America 94(7) 3408-3413.
Logothetis NK, Leopold DA and Sheinberg DL (April-1996) What is rivalling during binocular rivalry? Nature 380(6575) 621-624.
Logothetis NK and Sheinberg DL (March-1996) Visual Object Recognition Annual Review of Neuroscience 19 577-621.
Leopold DA and Logothetis NK (1996) Activity-Changes in Early Visual Cortex Reflect Monkeys' Percepts During Binocular Rivalry Nature 379(6565) 549-553.
Logothetis NK and Pauls J (May-1995) Psychophysical and physiological evidence for viewer-centered object representations in the primate Cerebral Cortex 5(3) 270-288.
Logothetis NK, Pauls J and Poggio T (May-1995) Shape Representation in the Inferior Temporal Cortex of Monkeys. Current Biology 5(5) 552-563.
Logothetis NK, Pauls J, Bülthoff HH and Poggio T (May-1994) View-dependent object recognition by monkeys. Current Biology 4(5) 401-414.
Logothetis NK (October-1991) Is movement perception color blind? Current Biology 1(5) 298-300.
Schiller PH, Logothetis NK and Charles ER (June-1991) Parallel pathways in the visual system: Their role in perception at isoluminance Neuropsychologia 29(6) 433-441.
Logothetis NK and Schall J (October-1990) Binocular motion rivalry in macaque monkeys: Eye dominance and tracking eye movements Vision Research 30(10) 1409-1419.
Schiller PH, Logothetis NK and Charles ER (October-1990) Role of the color-opponent and broad-band channels in vision Visual Neuroscience 5(4) 321-346.
Schiller PH and Logothetis NK (October-1990) The color-opponent and broad-band channels of the primate visual system Trends in Neurosciences 13(10) 392-398.
Logothetis NK and Charles ER (June-1990) The minimum motion technique applied to determine isoluminance in psychophysical experiments with monkeys Vision Research 30(6) 829-838.
Libet B and Logothetis NK (February-1990) "Subjective Perception" Science 247(4943) 727.
Schiller PH, Logothetis NK and Charles ER (January-1990) Functions of the colour-opponent and broad-band channels of the visual system Nature 343(6253) 68-70.
Logothetis NK, Schiller PH, Charles ER and Hurlbert AC (January-1990) Perceptual deficits and the activity of the color-opponent and broad-band pathways at isoluminance Science 247(4939) 214-217.
Logothetis NK and Schall JD (August-1989) Neuronal Correlates of Subjective Visual Perception Science 245(4919) 761-763.
Poeppel E and Logothetis NK (June-1988) Psychophysical correlates of physiological functions Brain and Behavioral Sciences 11(2) 308-309.
Pöppel E, Stoerig P, Logothetis NK, Fries W, Boergen K-P, Oertel W and Zihl J (October-1987) Plasticity and rigidity in the representation of the human visual field Experimental Brain Research 68(2) 445-448.
Pöppel E and Logothetis NK (May-1986) Neuronal oscillations in the human brain: Discontinuous initiations of pursuit eye movements indicate a 30-Hz temporal framework for visual information processing Naturwissenschaften 73(5) 263-268.

Conference papers (27):

Besserve M, Logothetis NK and Schölkopf B (2014) Statistical analysis of coupled time series with Kernel Cross-Spectral Density operators In: Advances in Neural Information Processing Systems 26, , Twenty-Seventh Annual Conference on Neural Information Processing Systems (NIPS 2013), Curran, Red Hook, NY, USA, 2537-2545.
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Logothetis NK (October-12-2012) What We Can and What We Can’t Do with fMRI, Society for Neuroscience: 2012 Short Course II MRI and Advanced Imaging in Animals and Humans, 7-14.
Biessmann F, Murayama Y, Logothetis NK, Müller K-R and Meinecke FC (2012) Non-separable Spatiotemporal Brain Hemodynamics Contain Neural Information In: Machine Learning and Interpretation in Neuroimaging, , NIPS Workshop on Machine Learning and Interpretation in Neuroimaging (MLINI 2011), Springer, Berlin, Germany, 140-147, Series: Lecture Notes in Computer Science ; 7263.
Sultan F, Augath M, Murayama Y, Tolias AS and Logothetis NK (December-2011) esfMRI of the upper STS: further evidence for the lack of electrically induced polysynaptic propagation of activity in the neocortex, 9th Workshop of the International School on Magnetic Resonance and Brain Function, Magnetic Resonance Imaging, 29(10), 1374-1381.
Besserve M, Janzing D, Logothetis NK and Schölkopf B (May-2011) Finding dependencies between frequencies with the kernel cross-spectral density, IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP 2011), IEEE, Piscataway, NJ, USA, 2080-2083.
Zhang H, Logothetis NK and Liang H (September-2009) Predicting perceptual suppression from local field potential in visual cortex, 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2009), IEEE, Piscataway, NJ, USA, 6802-6805.
Wang Z, Logothetis NK and Liang H (June-2009) Percept-related cortical induced activity during bistable perception, 2009 International Joint Conference on Neural Networks (IJCNN 2009), IEEE, Piscataway, NJ, USA, 3289-3296.
Tarr M, Behrmann M, Koch C, Malach R and Logothetis NK (July-2008) Rumelhart Symposium: Integrating Human and Machine Vision: In Honor of Shimon Ullman, 30th Conference of the Cognitive Science Society (CogSci 2008), Curran, Red Hook, NY, USA, 365-366.
Wang Z, Maier A and Logothetis NK (June-2008) Single-trial bistable perception classification based on sparse nonnegative tensor decomposition, International Joint Conference on Neural Networks (IJCNN 2008), IEEE, Piscataway, NJ, USA, 1041-1048.
Juchem C, Logothetis NK and Pfeuffer J (July-2007) 1H-MRS of the macaque monkey primary visual cortex at 7 T: strategies and pitfalls of shimming at the brain surface, 5th Workshop of the International School on Magnetic Resonance and Brain Function, Magnetic Resonance Imaging, 25(6), 902-912.
Goense JBM, Zappe A-C and Logothetis NK (July-2007) High-resolution fMRI of macaque V1, International School on Magnetic Resonance and Brain Function 2007, Magnetic Resonance Imaging, 25(6), 740-747.
Gretton A, Smola AJ, Bousquet O, Herbrich R, Belitski A, Augath M, Murayama Y, Pauls J, Schölkopf B and Logothetis NK (January-2005) Kernel Constrained Covariance for Dependence Measurement, Tenth International Workshop on Artificial Intelligence and Statistics (AISTATS 2005), Society for Artificial Intelligence and Statistics, Fort Lauderdale, FL, USA, 112-119.
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Pfeuffer J, Juchem C, Merkle H, Nauerth A and Logothetis NK (December-2004) High-field localized 1H NMR spectroscopy in the anesthetized and in the awake monkey In: Frontiers of Brain Functional MRI and Electrophysiological Methods, , International School on Magnetic Resonance and Brain Function 2004, Magnetic Resonance Imaging, 22(10), 1361-1372.
Logothetis NK and Pfeuffer J (December-2004) On the Nature of the BOLD fMRI Contrast Mechanism In: Frontiers of Brain Functional MRI and Electrophysiological Methods, , International School on Magnetic Resonance and Brain Function 2004, Magnetic Resonance Imaging, 22(10), 1517-1531.
Juchem C, Merkle H, Schick F, Logothetis NK and Pfeuffer J (December-2004) Region and volume dependencies in spectral linewidth assessed by 1H 2D MR chemical shift imaging in the monkey brain at 7T In: Frontiers of Brain Functional MRI and Electrophysiological Methods, , International School on Magnetic Resonance and Brain Function 2004, Magnetic Resonance Imaging, 22(10), 1373-1383.
Görür D, Rasmussen CE, Tolias AS, Sinz F and Logothetis NK (September-2004) Modelling Spikes with Mixtures of Factor Analysers In: Pattern Recognition, , 26th Annual Symposium of the German Association for Pattern Recognition (DAGM 2004), Springer, Berlin, Germany, 391-398, Series: Lecture Notes in Computer Science ; 3175.
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Eichhorn J, Tolias AS, Zien A, Kuss M, Rasmussen CE, Weston J, Logothetis NK and Schölkopf B (June-2004) Prediction on Spike Data Using Kernel Algorithms In: Advances in Neural Information Processing Systems 16, , Seventeenth Annual Conference on Neural Information Processing Systems (NIPS 2003), MIT Press, Cambridge, MA, USA, 1367-1374.
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Last updated: Monday, 22.05.2017