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Prof. Dr. Nikos Logothetis

Address: Spemannstr. 38
72076 Tübingen
Room number: 121
Phone: +49 7071 601 651
Fax: +49 7071 601 652
E-Mail: nikos.logothetis

 

Picture of Logothetis, Nikos, Prof. Dr.

Nikos Logothetis

Position: Director  Unit: Logothetis

Research in this laboratory concentrates on the neural mechanisms of perception and object recognition. Although our basic research revolves around vision, a number of independent collaborators are also investigating the relationship between neural activity and perception using other sensory modalities. I firmly believe that such scientific questions require a multimodal methodological approach that integrates information obtained from single units with that derived from mass action potentials as well as from a number of activity-related, surrogate signals such as those monitored during noninvasive experiments. Parallel to our ongoing research, therefore, we are also working to develop methodologies that will permit us to study neural networks in the context of behavioral paradigms. We have already designed and implemented two high-field magnetic resonance imaging systems for functional, anatomical and spectroscopic imaging. The systems are endowed with all the necessary hard- and software to conduct simultaneous imaging and recordings, and they are being used to study the function, connectivity, and neurochemistry of the non-human primate brain. Furthermore, while continuing to exploit traditional neuroimaging in our experiments, we are also investigating the relationship of neural activity to the MR-measurable hemodynamic responses and experimenting with methods that do not rely on hemodynamic responses at all. In the context of the last-named project, a group of synthetic and coordination chemists in my laboratory are attempting to synthesize and evaluate MR-detectable smart probes that change magnetic properties as a function of the concentration of ions and molecules involved in neural signaling. Smart contrast agents, if designed and tested appropriately, promise to revolutionize invasive neuroimaging and would represent a quantum leap forward in signal-to-noise ratio, spatial detail and specificity, while affording unprecedented temporal resolution.
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Nikos K. Logothetis is director of the department “Physiology of Cognitive Processes” at the Max Planck Institute for Biological Cybernetics (MPIK), in Tübingen, Germany. He received a B.S. in mathematics from the University of Athens, a B.S. in biology from the University of Thessaloniki, and his Ph.D. in human neurobiology from the Ludwig-Maximilians University in Munich. In 1985 he moved to the Brain and Cognitive Sciences Department of M.I.T., where he initially worked as a postdoctoral fellow and later as Research Scientist. In 1990 he joined the faculty of the Division of Neuroscience at the Baylor College of Medicine. Seven years later he moved to the Max Planck Institute for Biological Cybernetics to continue his work on the physiological mechanisms underlying visual perception and object recognition.

In addition to visual cognition, his work at MPIC includes auditory perception and multisensory integration, as well as studies of plasticity and neuromodulation. Parallel to this ongoing research, a number of methods have been developed that permit the study of neural networks in the context of behavioral paradigms. Two high-field magnetic resonance imaging systems were designed and implemented for functional, anatomical and spectroscopic imaging. They permit simultaneous imaging and intracortical recordings and are being used to study the function, connectivity, and neurochemistry of the non-human primate brain, as well as the relationship of neural activity to the MR-measurable hemodynamic responses. Last but not least a group of synthetic and coordination chemists at MPIC are attempting to synthesize and evaluate MR-detectable smart probes that change magnetic properties as a function of the concentration of ions and molecules involved in neural signaling.

Since 1992 Nikos K. Logothetis has been Adjunct Professor of Neurobiology at the Salk Institute in San Diego, since 1995 Adjunct Professor of Ophthalmology at the Baylor College of Medicine, Houston, Associate of the Neurosciences Institute, San Diego, Senior Visiting Fellow in University College, London, Adjunct Professor in the Department of Cognitive and Neural Systems and of Cognitive and Neural Systems in the College of Arts and Sciences, both at the Boston University, Massachusetts, a  faculty member at the Victoria University of Manchester (VUM) in England, and Honorary Professor in the Department of Biology at the University of Tübingen.

Nikos K. Logothetis has been or continues to be a member of the Advisory Boards of McGovern Institute, M.I.T.; Brain and Cognitive Sciences, M.I.T., USA; POSIT Science Corporation, San Francisco, USA; IGPS, Freiburg, Germany; Centre of Excellence in Systems Neuroscience of the Academy of Finland, Helsinki, Finland; Brain Imaging Center, Frankfurt am Main, Germany; ICM-ADREC, Paris, France; Brain Center of the Hebrew University, Jerusalem, Israel, and in the Advisory Board of the Brain Research Center of the Weizmann Institute, Jerusalem, Israel.  He served as Receiving Editor for the European Journal of Neuroscience (EJN), Associate Editor for Trends in Cognitive Sciences (TICS), Neuron, Current Biology, Current Opinion Neurobiology, and is a regular reviewer for Nature, Nature Neuroscience, J Neuroscience, PNAS, Cerebral Cortex, Cerebral Blood Flow and Metabolism, Journal of Neurophysiology, Experimental Brain Research, and Vision Research. He is a member of the Society for Neuroscience, European Neuroscience Association, American Association for the Advancement of Science, Association for Research in Vision and Ophthalmology, New York Academy of Sciences, Society for Industrial and Applied Mathematics, American Mathematical Society, International Neuropsychological Society, and Mathematical Association of America.

Nikos K. Logothetis is member of the German Academy of Natural Scientists Leopoldina, of the Rodin Remediation Academy, Honorary Member of the American Academy of Arts and Sciences, and a foreign associate of the National Academy of Sciences of the United States. He is recipient of the DeBakey Award for Excellence in Science, the Golden Brain Award of the Minerva Foundation, the 2003 Louis-Jeantet Prize of Medicine, the 2004 Zülch-Price for Neuroscience, the 2007 IPSEN Prize for Neuronal Plasticity, and the 2008 Alden Spencer Award of Columbia University, New York.

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Talks (149):

Logothetis NK (August-2009): Neurovascular coupling: insights from physiology, neuropharmacology and electrical microstimulation, 32nd European Conference on Visual Perception, Regensburg, Germany, Perception, 38(ECVP Abstract Supplement) 114.
Perrodin C, Kayser C, Logothetis NK and Petkov C (June-30-2009) Abstract Talk: Visual influences on voice-selective neurons in the anterior superior-temporal plane, 10th International Multisensory Research Forum (IMRF 2009), New York City, USA(539).
Aggelopoulos NC, Liebe S, Logothetis NK and Rainer G (May-2009) Abstract Talk: Dependence of a cognitive task on acetylcholine, Data Mining in Biomedicine Conference at the Athens Institute of Technology (DMINBIO-09), Athens, Greece.
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Logothetis NK (March-26-2009) Keynote Lecture: Electrical Microstimulation and fMRI, 8th Göttingen Meeting of the German Neuroscience Society, 32nd Göttingen Neurobiology Conference, Göttingen, Germany 12.
Ku S-P, Gretton A, Macke J and Logothetis NK (October-2008) Abstract Talk: Pattern recognition methods in classifying fMRI data, 9th Conference of the Junior Neuroscientists of Tübingen (NeNa 2008), Ellwangen, Germany 11.
Rauch A, Meinec FC, Biessmann F, Müller K-R, Logothetis NK and Rainer G (October-2008) Abstract Talk: The effect of a serotonine agonist on neural activity and BOLD activity in monkey primary visual cortex, a pharmacological fMRI (PhMRI) study, Bernstein Symposium 2008, München, Germany, Frontiers in Computational Neuroscience, Conference Abstract: Bernstein Symposium 2008.
Logothetis NK, Wandell B and Smirnakis SM (September-2008) Abstract Talk: Macaque fMRI For Studying Cortical Reorganization, 10th International Conference on Cognitive Neuroscience, Bodrum, Turkey, Frontiers in Human Neuroscience, Conference Abstract: 10th International Conference on Cognitive Neuroscience.
Bartels A, Panagiotaropoulos T, Keliris GA and Logothetis NK (September-2008) Abstract Talk: On the neural mechanisms of binocular rivalry, 10th International Conference on Cognitive Neurosciences (ICON 2008), Bodrum, Turkey, Frontiers in Human Neuroscience, Conference Abstract: 10th International Conference on Cognitive Neuroscience.
Logothetis NK (July-10-2008): Neurovascular Coupling: Insights from Physiology, Neuropharmacology & Electrical Microstimulation, Berlin BCI Workshop 2009: Advances in Nanotechnology, Berlin, Germany.
Tsuchiya N, Maier A, Logothetis NK and Leopold D (June-21-2008) Abstract Talk: Decoding Monkey’s Conscious Experience during Ambiguous and Unambiguous Motion Percept Reveals Initial Non-conscious Spike Activity and Later Neuronal Correlates of Consciousness in Area MT, 12th Annual Meeting of the Association for the Scientific Study of Consciousness (ASSC 2008), Taipei, Taiwan 227-228.
Zappe A-C, Uludag K and Logothetis NK (May-9-2008) Abstract Talk: Negative BOLD Signal Under 6% Hypercapnia Reflects Solely Oxygen Extraction from the Blood, 16th Scientific Meeting and Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2008), Toronto, Canada 166.
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Chaimow D, Logothetis NK, Raddatz G, Shmuel A, Ugurbil K and Yacoub E (May-5-2008) Abstract Talk: Multi-resolution classification analysis of ocular dominance columns obtained from human V1 at 7 Tesla: mechanisms underlying decoding signals, 16th Scientific Meeting and Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2008), Toronto, Canada 27.
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Goense JBM and Logothetis NK (May-5-2008) Abstract Talk: Positive and negative BOLD-signals from blood vessels in monkey visual cortex, 16th Scientific Meeting and Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2008), Toronto, Canada 27.
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Tsuchiya N, Maier A, Logothetis NK and Leopold D (April-2008) Abstract Talk: Decoding monkey's conscious experience during ambiguous and unambiguous motion percept reveals initial non-conscious spike activity and later neuronal correlates of consciousness in area MT, Eighth Biennial Tucson Conference:Toward a Science of Consciousness 2008, Tucson, AZ, USA 89.
Dhingra K, Maier ME and Logothetis NK (November-28-2007) Abstract Talk: Smart Contrast Agent in Magnetic Resonance Imaging, 8th Conference of Tuebingen Junior Neuroscientists (NeNa 2007), Freudenstadt, Germany 17.
Logothetis NK (November-26-2007) Invited Lecture: From Single Neuron Activity to Visual Cognition: A Bridge Too Far?, University of Cambridge: Adrian Seminars in Neuroscience, Cambridge, UK.
Schmid MC, Panagiotaropoulos T, Augath MA, Logothetis NK and Smirnakis SM (November-2007) Abstract Talk: Areas V2 and V3 remain active and retinotopically organized in the absence of direct V1 input, 37th Annual Meeting of the Society for Neuroscience (Neuroscience 2007), San Diego, CA, USA(122.2).
Sigala Alanis GR, Nielsen KJ, Logothetis NK and Rainer G (November-2007) Abstract Talk: Decoding the human/monkey face category boundary from the macaque inferior-temporal (IT) cortex using 3D human/monkey morphed faces, 37th Annual Meeting of the Society for Neuroscience (Neuroscience 2007), San Diego, CA, USA(554.8).
Corrado GS, Sugrue LP, Brown JR, Logothetis NK and Newsome WT (November-2007) Abstract Talk: Interspecies fMRI in Monkeys and Humans engaged in value-based decision making, 37th Annual Meeting of the Society for Neuroscience (Neuroscience 2007), San Diego, CA, USA(232.5).
Sultan FR, Augath M, Hammodeh S, Oeltermann A and Logothetis NK (November-2007) Abstract Talk: Microstimulation-evoked BOLD responses of the macaque cerebellar cortex, 37th Annual Meeting of the Society for Neuroscience (Neuroscience 2007), San Diego, CA, USA(339.3).
Shmuel A, Raddatz G, Chaimow D, Logothetis NK, Ugurbil K and Yacoub E (November-2007) Abstract Talk: Multi-resolution classification analysis of ocular dominance columns obtained at 7 Tesla from human V1: mechanisms underlying decoding signals, 37th Annual Meeting of the Society for Neuroscience (Neuroscience 2007), San Diego, CA, USA(451.9).
Liebe S, Logothetis NK and Rainer G (November-2007) Abstract Talk: Specialization for natural image color processing in extrastriate (V4) but not prefrontal (PF) neurons, 37th Annual Meeting of the Society for Neuroscience (Neuroscience 2007), San Diego, CA, USA(229.5).
Logothetis NK (September-2007) Invited Lecture: Electrical Microstimulation and fMRI, Third Cold Spring Harbor Laboratory/Wellcome Trust Conference on Integrative Approaches to Brain Complexity, Hinxton, UK.
Tolias AS, Ecker A, Keliris GA, Panagiotaropolulos F, Panzeri S and Logothetis NK (September-2007) Abstract Talk: Population codes, correlations and coding uncertainty, Neural Coding, Computation and Dynamics (NCCD 07), Hossegor, France 16.
Logothetis NK (July-2007) Invited Lecture: In Vivo Connectivity: MRI, Paramagnetic Tracers and Electrical Stimulation, 7th IBRO World Congress of Neuroscience, Melbourne, Australia.
Logothetis NK (July-2007) Invited Lecture: The Effects of Adaptation on Direction-Selectivity of V4 Neurons, 7th IBRO World Congress of Neuroscience, Melbourne, Australia.
Zappe A-C, Logothetis NK and Goense JBM (May-23-2007) Abstract Talk: Spatial specificity of CBV and BOLD fMRI in monkey striate cortex at 4.7T and 7T, 2007 Joint Annual Meeting ISMRM-ESMRMB, Berlin, Germany 136.
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Dahl CD, Logothetis NK and Hoffman KL (March-2007) Abstract Talk: Hallmarks of face processing in Rhesus monkeys, 49. Tagung Experimentell Arbeitender Psychologen (TeaP 2007), Trier, Germany 166.
Huddleston WE and Logothetis NK (October-2006) Abstract Talk: Adaptation lengthens stimulus suppression time during binocular rivalry, 36th Annual Meeting of the Society for Neuroscience (Neuroscience 2006), Atlanta, GA, USA(309.4).
Logothetis NK, Sultan F, Murayama Y, Augath M, Steudel T and Oeltermann A (October-2006) Abstract Talk: Microstimulation and fMRI in anesthetized and alert monkeys: Conditions for transsynaptic BOLD activation, 36th Annual Meeting of the Society for Neuroscience (Neuroscience 2006), Atlanta, GA, USA(114.10).
Sultan FR, Augath M, Oeltermann A, Tolias AS and Logothetis NK (October-2006) Abstract Talk: Microstimulation of the upper posterior bank of the STS, 36th Annual Meeting of the Society for Neuroscience (Neuroscience 2006), Atlanta, GA, USA(114.9).
Reichold J, Zappe A-C, Burger C, Weber B, Buck A, Pfeuffer J and Logothetis NK (September-22-2006) Abstract Talk: Application of two-compartmental model on non-human primate perfusion data: quantification and sensitivity mapping, 23rd Annual Scientific Meeting of the ESMRMB 2006, Warsaw, Poland, Magnetic Resonance Materials in Physics, Biology and Medicine, 19(Supplement 1) 121-122.
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Logothetis NK (September-21-2006) Abstract Talk: Combining MRI with invasive neuroscientific techniques: An attempt to study distributed neural networks, 23rd Annual Scientific Meeting of the ESMRMB 2006, Warsaw, Poland, Magnetic Resonance Materials in Physics, Biology and Medicine, 19(Supplement 1) 8.
Zappe A-C, Goense JBM, Logothetis NK and Pfeuffer J (September-21-2006) Abstract Talk: The effect of post labeling delay on specificity of the fCBF signal in monkey striate cortex, 23rd Annual Scientific Meeting of the ESMRMB 2006, Warsaw, Poland, Magnetic Resonance Materials in Physics, Biology and Medicine, 19(Supplement 1) 64.
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Bondar IV, Leopold D and Logothetis NK (August-2006) Abstract Talk: Pattern-selective cortical neurons show long-term stability in their stimulus preferences and temporal dynamics, 29th European Conference on Visual Perception, St. Petersburg, Perception, 35(ECVP Abstract Supplement) 121-122.
Mishra A, Mamedov I, Pfeuffer J, Angelovski G, Laurent S, van der Elst L, Müller R, Lubal P, Logothetis NK and Mayer H (June-2006) Abstract Talk: DO3A-Based mono(alkylphosphonate) complexes as potential pH-sensitive contrast agents for MR Imaging, 10th Bi-Annual Conference of the European Magnetic Resonance Forum (EMRF 2006), Vilnius, Lithuania.
Juchem C, Logothetis NK and Pfeuffer J (May-8-2006) Abstract Talk: Localized 1H MR Spectroscopy in the Primary Visual Cortex (V1) of the Macaque Monkey, 14th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2006), Seattle, WA, USA 33.
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Logothetis NK (May-2006) Invited Lecture: Neural Events Underlying the BOLD Signal: Combined Electrophysiology and fMRI, 4th Course: Magnetic Resonance Combined with Electrophysiology and with Molecular and Pharmaceutical Action for the Study of Brain Function (EMFCSC 2006), Erice, Italy.
Petkov CI, Kayser C, Augath M, Steudel T and Logothetis NK (November-11-2005) Abstract Talk: High-Field fMRI Reveals Auditory Cortical Fields in the Macaque Monkey, Tucker-Davis Symposium on Advances and Perspectives in Auditory Neurophysiology (APAN III), Washinton, DC, USA.
Maier JX, Logothetis NK and Ghazanfar AA (November-11-2005) Abstract Talk: Looming versus receding signals in rhesus monkey auditory cortex, Tucker-Davis Symposium on Advances and Perspectives in Auditory Neurophysiology (APAN III), Washinton, DC, USA.
Sereno ME, Augath M and Logotethis NK (November-2005) Abstract Talk: Differences in processing of 3-D shape from multiple cues in monkey cortex revealed by fMRI, 35th Annual Meeting of the Society for Neuroscience (Neuroscience 2005), Washington, DC, USA(362.9).
Zappe A-CC, Uludaq K, Rainer G and Logothetis NK (November-2005) Abstract Talk: Influence of moderate hypercapnia on neural activity in monkey by simultaneous intracortical recordings and fMRI at 4.7T, 35th Annual Meeting of the Society for Neuroscience (Neuroscience 2005), Washington, DC, USA(10.11).
Nielsen KJ, Logothetis NK and Rainer G (November-2005) Abstract Talk: Local field potentials recorded from macaque TE reveal posterior to anterior gradient in the extraction of diagnostic elements from natural scenes, 35th Annual Meeting of the Society for Neuroscience (Neuroscience 2005), Washington, DC, USA(362.2).
Tolias AS, Keliris GA, Ecker AS, Siapas AG, Smirnakis SM and Logothetis NK (November-2005) Abstract Talk: Structure of interneuronal correlations in the primary visual cortex of the Rhesus macaque, 35th Annual Meeting of the Society for Neuroscience (Neuroscience 2005), Washington, DC, USA(591.12).
Logothetis NK (September-2005) Keynote Lecture: Neural Mass Actions Studied with Electrophysiology and Functional Magnetic Resonance Imaging, 45th Annual Meeting of the Society for Psychophysiological Research, Lisboa, Portugal, Psychophysiology, 42(Supplement 1) 1.
Keller AL, Weber B and Logothetis NK (September-2005) Abstract Talk: Quantification of the Layer Specific Vascular Density using anti-Collagen Fluorescence Immunohistochemistry in the Primate Striate and Extrastriate Cortex, Microscopy Conference 2005: 6. Dreiländertagung, Davos, Switzerland 177.
Pfeuffer J, Juchem C, Merkle H and Logothetis NK (May-11-2005) Abstract Talk: Localized 1H MR spectroscopy in the alert monkey at 7 Tesla, 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2005), Miami Beach, FL, USA 120.
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Logothetis NK (May-2005) Invited Lecture: fMRI studies on casualty in the human brain, 3rd Course: Brain Function Research by Magnetic Resonance, Electrophysiology and Molecular Probes, Erice, Italy.
Shmuel A, Augath M, Oeltermann A, Pauls J and Logothetis NK (October-23-2004) Abstract Talk: Linking the negative BOLD response to decreases in neuronal activity in monkey V1, 34th Annual Meeting of the Society for Neuroscience (Neuroscience 2004), San Diego, CA, USA(18.14).
Smirnakis SM, Brewer AA, Schmid M, Tolias AS, Augath M, Inhoffen W, Schüz A, Wandell BA and Logothetis NK (October-2004) Abstract Talk: V1 cortical reorganization revisited: fMRI and electrophysiology in macaque following retinal lesions, 34th Annual Meeting of the Society for Neuroscience (Neuroscience 2004), San Diego, CA, USA(605.3).
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Last updated: Monday, 22.05.2017