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Prof. Dr. Nikos Logothetis

Address: Spemannstr. 38
72076 Tübingen
Room number: 121
Phone: +49 7071 601 651
Fax: +49 7071 601 652
E-Mail: nikos.logothetis

 

Picture of Logothetis, Nikos, Prof. Dr.

Nikos Logothetis

Position: Director  Unit: Logothetis

Research in this laboratory concentrates on the neural mechanisms of perception and object recognition. Although our basic research revolves around vision, a number of independent collaborators are also investigating the relationship between neural activity and perception using other sensory modalities. I firmly believe that such scientific questions require a multimodal methodological approach that integrates information obtained from single units with that derived from mass action potentials as well as from a number of activity-related, surrogate signals such as those monitored during noninvasive experiments. Parallel to our ongoing research, therefore, we are also working to develop methodologies that will permit us to study neural networks in the context of behavioral paradigms. We have already designed and implemented two high-field magnetic resonance imaging systems for functional, anatomical and spectroscopic imaging. The systems are endowed with all the necessary hard- and software to conduct simultaneous imaging and recordings, and they are being used to study the function, connectivity, and neurochemistry of the non-human primate brain. Furthermore, while continuing to exploit traditional neuroimaging in our experiments, we are also investigating the relationship of neural activity to the MR-measurable hemodynamic responses and experimenting with methods that do not rely on hemodynamic responses at all. In the context of the last-named project, a group of synthetic and coordination chemists in my laboratory are attempting to synthesize and evaluate MR-detectable smart probes that change magnetic properties as a function of the concentration of ions and molecules involved in neural signaling. Smart contrast agents, if designed and tested appropriately, promise to revolutionize invasive neuroimaging and would represent a quantum leap forward in signal-to-noise ratio, spatial detail and specificity, while affording unprecedented temporal resolution.
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Nikos K. Logothetis is director of the department “Physiology of Cognitive Processes” at the Max Planck Institute for Biological Cybernetics (MPIK), in Tübingen, Germany. He received a B.S. in mathematics from the University of Athens, a B.S. in biology from the University of Thessaloniki, and his Ph.D. in human neurobiology from the Ludwig-Maximilians University in Munich. In 1985 he moved to the Brain and Cognitive Sciences Department of M.I.T., where he initially worked as a postdoctoral fellow and later as Research Scientist. In 1990 he joined the faculty of the Division of Neuroscience at the Baylor College of Medicine. Seven years later he moved to the Max Planck Institute for Biological Cybernetics to continue his work on the physiological mechanisms underlying visual perception and object recognition.

In addition to visual cognition, his work at MPIC includes auditory perception and multisensory integration, as well as studies of plasticity and neuromodulation. Parallel to this ongoing research, a number of methods have been developed that permit the study of neural networks in the context of behavioral paradigms. Two high-field magnetic resonance imaging systems were designed and implemented for functional, anatomical and spectroscopic imaging. They permit simultaneous imaging and intracortical recordings and are being used to study the function, connectivity, and neurochemistry of the non-human primate brain, as well as the relationship of neural activity to the MR-measurable hemodynamic responses. Last but not least a group of synthetic and coordination chemists at MPIC are attempting to synthesize and evaluate MR-detectable smart probes that change magnetic properties as a function of the concentration of ions and molecules involved in neural signaling.

Since 1992 Nikos K. Logothetis has been Adjunct Professor of Neurobiology at the Salk Institute in San Diego, since 1995 Adjunct Professor of Ophthalmology at the Baylor College of Medicine, Houston, Associate of the Neurosciences Institute, San Diego, Senior Visiting Fellow in University College, London, Adjunct Professor in the Department of Cognitive and Neural Systems and of Cognitive and Neural Systems in the College of Arts and Sciences, both at the Boston University, Massachusetts, a  faculty member at the Victoria University of Manchester (VUM) in England, and Honorary Professor in the Department of Biology at the University of Tübingen.

Nikos K. Logothetis has been or continues to be a member of the Advisory Boards of McGovern Institute, M.I.T.; Brain and Cognitive Sciences, M.I.T., USA; POSIT Science Corporation, San Francisco, USA; IGPS, Freiburg, Germany; Centre of Excellence in Systems Neuroscience of the Academy of Finland, Helsinki, Finland; Brain Imaging Center, Frankfurt am Main, Germany; ICM-ADREC, Paris, France; Brain Center of the Hebrew University, Jerusalem, Israel, and in the Advisory Board of the Brain Research Center of the Weizmann Institute, Jerusalem, Israel.  He served as Receiving Editor for the European Journal of Neuroscience (EJN), Associate Editor for Trends in Cognitive Sciences (TICS), Neuron, Current Biology, Current Opinion Neurobiology, and is a regular reviewer for Nature, Nature Neuroscience, J Neuroscience, PNAS, Cerebral Cortex, Cerebral Blood Flow and Metabolism, Journal of Neurophysiology, Experimental Brain Research, and Vision Research. He is a member of the Society for Neuroscience, European Neuroscience Association, American Association for the Advancement of Science, Association for Research in Vision and Ophthalmology, New York Academy of Sciences, Society for Industrial and Applied Mathematics, American Mathematical Society, International Neuropsychological Society, and Mathematical Association of America.

Nikos K. Logothetis is member of the German Academy of Natural Scientists Leopoldina, of the Rodin Remediation Academy, Honorary Member of the American Academy of Arts and Sciences, and a foreign associate of the National Academy of Sciences of the United States. He is recipient of the DeBakey Award for Excellence in Science, the Golden Brain Award of the Minerva Foundation, the 2003 Louis-Jeantet Prize of Medicine, the 2004 Zülch-Price for Neuroscience, the 2007 IPSEN Prize for Neuronal Plasticity, and the 2008 Alden Spencer Award of Columbia University, New York.

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Posters (573):

Pauls J and Logothetis NK (1994): Neuronal Correlates of Visual Object Recognition in the Nonhuman Primate, Neuroscience Forum 1994, Houston, TX, USA.
Logothetis NK, Pauls J, Bülthoff HH and Poggio T (November-1993): Responses of Inferotemporal (IT) Neurons to Novel Wire-Objects in Monkeys Trained in an Object Recognition Task, 23rd Annual Meeting of the Society for Neuroscience (Neuroscience 1993), Washington, DC, USA.
Logothetis NK, Pauls J, Bülthoff HH and Poggio T (May-1993): Evidence for recognition based on interpolation among 2D views of objects in monkeys, Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO 1993), Sarasota, FL, USA, Investigative Ophthalmology & Visual Science, 34(4) 1132.
Charles EC and Logothetis NK (May-1990): MT responses to drifting low contrast homochromatic and heterochromatic gratings, Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO 1990), Sarasota, FL, USA, Investigative Ophthalmology & Visual Science, 31(Supplement) 238.
Poeppel DE and Logothetis NK (May-1990): Stereopsis in monkeys with achromatic and chromatic random dot stereograms, Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO 1990), Sarasota, FL, USA, Investigative Ophthalmology & Visual Science, 31(Supplement) 89.
Lee K, Schiller PH and Logothetis NK (May-1990): The effects of LGN, V4 and MT lesions on visually guided eye movements to moving targets, Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO 1990), Sarasota, FL, USA, Investigative Ophthalmology & Visual Science, 30(Supplement) 323.
Schiller P, Logothetis NK, Charles ER and Lee K (May-1990): The effects of LGN, V4 and MT lesions on visually guided eye movements to stationary targets, Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO 1990), Sarasota, FL, USA, Investigative Ophthalmology & Visual Science, 31(Supplement) 399.
Logothetis NK and Charles ER (May-1990): V4 Responses to gratings defined by random dot motion, Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO 1990), Sarasota, FL, USA, Investigative Ophthalmology & Visual Science, 31(Supplement) 90.
Poeppel DE and Logothetis NK (May-1989): Chrominance information can be used by the oculomotor system to program saccades to moving targets, Annual Spring Meeting of the Association for Research in Vision and Ophthalmology (ARVO 1989), Sarasota, FL, USA, Investigative Ophthalmology & Visual Science, 30(3) 112.
Schiller PH, Logothetis NK and Charles ER (May-1989): The functions of the color-opponent (C-O) and Broad-Band (B-B) channels in perception at isoluminance, Annual Spring Meeting of the Association for Research in Vision and Ophthalmology (ARVO 1989), Sarasota, FL, USA, Investigative Ophthalmology & Visual Science, 30(3) 323.
Logothetis NK and Charles ER (May-1989): The minimum-motion stimulus for defining isoluminance in the macaque monkey at various spatial and temporal frequencies, Annual Spring Meeting of the Association for Research in Vision and Ophthalmology (ARVO 1989), Sarasota, FL, USA, Investigative Ophthalmology & Visual Science, 30(3) 427.
Charles EC and Logothetis NK (May-1989): The responses of middle temporal (MT) neurons to isoluminant stimuli, Annual Spring Meeting of the Association for Research in Vision and Ophthalmology (ARVO 1989), Sarasota, FL, USA, Investigative Ophthalmology & Visual Science, 30(3) 427.
Logothetis NK and Schall JD (November-1988): Motion rivalry used to study neuronal activity underlying motion perception, 18th Annual Meeting of the Society for Neuroscience (Neuroscience 1988), Toronto, Canada.
Schiller PH, Logothetis NK and Charles ER (November-1988): The role of the color-opponent (C-O) and broad-band (B-B) channels in vision, 18th Annual Meeting of the Society for Neuroscience (Neuroscience 1988), Toronto, Ccanada.
Hurlbert AC and Logothetis NK (May-1988): Color matching in monkeys and humans: quantitative studies of color constancy and color contrast, Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO 1988), Sarasota, FL, USA, Investigative Ophthalmology & Visual Science, 29(Supplement) 301.
Logothetis NK and Charles ER (May-1988): Monkey pursuit eye movements in response to moving isoluminant gratings, Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO 1988), Sarasota, FL, USA, Investigative Ophthalmology & Visual Science, 29(Supplement) 328.
Schiller PH, Charles ER and Logothetis NK (May-1988): The effect of V4 and parvocellular LGN lesions on primate vision, Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO 1988), Sarasota, FL, USA, Investigative Ophthalmology & Visual Science, 29(Supplement) 328.
Logothetis NK, Vogels R and Schiller PH (November-1987): Neuronal activity in V1, V2, and V4 in macaque monkey, 17th Annual Meeting of the Society for Neuroscience (Neuroscience 1987), New Orleans, LA, USA.
Schiller PH and Logothetis NK (November-1987): The effect of frontal eye field and superior colliculus lesions on the saccadic and pursuit eye movement initiation, 17th Annual Meeting of the Society for Neuroscience (Neuroscience 1987), New Orleans, LA, USA.
Charles ER, Logothetis NK, Hurlbert AC and Schiller PH (November-1987): The processing of color and luminance information in monkeys: II. Psychophysics, 17th Annual Meeting of the Society for Neuroscience (Neuroscience 1987), New Orleans, LA, USA.
Fries W, Logothetis NK, Oertel W and Poeppel E (July-1983): Dissociation of sensory and motor maps in the human visual system after visual misalignment due to congenital monocular squint, Meeting of the Physiological Society and Association des Physiologistes, Oxford, UK, Journal of Physiology, 345(Supplement) 125P.

Popular Scientific Articles (3):

Schüz A and Logothetis NK: Valentin Braitenberg: Nachruf, Jahresbericht der Max-Planck-Gesellschaft 2011.
Logothetis NK: Wo unser Gehirn das zusammenführt, was gehört und gefühlt wird - Forschungsbericht 2006 Max-Planck-Institut für biologische Kybernetik, Jahrbuch der Max-Planck-Gesellschaft 2006, 1-4.
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Logothetis NK: Funktionelle Kernspintomographie des Affengehirns - Tätigkeitsbericht 2003, Jahrbuch der Max-Planck-Gesellschaft 2003, 1-6.
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Talks (149):

Takemura H, Pestilli F, Weiner KS, Keliris G, Landi S, Sliwa J, Ye F, Barnett M, Leopold D, Freiwald W, Logothetis NK and Wandell B (August-2017) Abstract Talk: Comparative neuroanatomy of occipital white matter tracts in human and macaque, 17th Annual Meeting of the Vision Sciences Society (VSS 2017), St. Pete Beach, FL, USA, Journal of Vision, 17(10) 589.
Logothetis NK (June-18-2017) Invited Lecture: Electrical microstimulation: Mapping monosynaptic connectivity & cortico-thalamo-cortical loops, Hanse-Wissenschaftskolleg Workshop: Specificity Versus Generality of (Visual) Cortex, Delemenhorst, Germany.
Logothetis NK (June-12-2017) Invited Lecture: NET-fMRI of large-scale brain networks: mapping dynamic connectivity in epochs of synaptic and system consolidation, Spring Hippocampal Research Conference, Taormina, Italy.
Takemura H, Pestilli F, Weiner K, Keliris G, Landi S, Sliwa J, Ye F, Barnett M, Leopold D, Freiwald F, Logothetis NK and Wandell B (April-24-2017) Abstract Talk: Using diffusion MRI and tractography to identify macaque vertical occipital fasciculus, 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017), Honolulu, HI, USA 95.
Logothetis NK (April-7-2017) Invited Lecture: Electrical Microstimulation: Mapping Monosynaptic Connectivity & Cortico-Thalamo-Cortical Loops, Boston University, Boston, MA, USA.
Logothetis NK, Murayama Y, Ramirez-Villegas J, Besserve M and Evrard H (November-16-2016) Abstract Talk: PGO wave-triggered functional MRI: mapping the networks underlying synaptic consolidation, 46th Annual Meeting of the Society for Neuroscience (Neuroscience 2016), San Diego, CA, USA(670.12).
Logothetis NK (October-14-2016) Invited Lecture: NET-fMRI of Large-Scale Brain Networks: Mapping Dynamic Connectivity in Epochs of Synaptic and System Consolidation, Stanford Talks: CNI Fifth Year Celebration, Stanford, CA, USA.
Logothetis NK (July-18-2016) Invited Lecture: Electrical Stimulation: Mapping mononsynaptic connectivity and cortico-thalamo-cortical loops, 2016 UCLA Advanced Neuroimaging Summer Program, Los Angeles, CA, USA.
Logothetis NK (July-18-2016) Invited Lecture: NET-fMRI of Large-Scale Brain Networks, 2016 UCLA Advanced Neuroimaging Summer Program, Los Angeles, CA, USA.
Kaplan R, King J, Koster R, Adhikari MH, Hindriks R, Murayama Y, Penny WJ, Mantini D, Burgess N, Logothetis NK, Deco N and Friston KJ (July-18-2016) Abstract Talk: Relating rapid mental simulation to past experience, 6th International Conference on Memory (ICOM-6), Budapest, Hungary 59.
Safavi S, Dwarakanath A, Besserve M, Kapoor V, Logothetis NK and Panagiotaropoulos TI (June-2016) Abstract Talk: A Non-Monotonic Correlation Structure in the Macaque Ventrolateral Prefrontal Cortex, AREADNE 2016: Research in Encoding And Decoding of Neural Ensembles, Santorini, Greece 53.
Logothetis NK (February-14-2016) Invited Lecture: NET-fMRI of Large-Scale Brain Networks: Mapping Dynamic Connectivity in Epochs of Synaptic and System Consolidation, Gordon Research Conference: Thalamocortical Interactions - Cell and Circuit Properties of Thalamocortical Interactions, Ventura, CA, USA.
Dwarakanath A, Safavi S, Kapoor V, Logothetis NK and Panagiotaropoulos T (November-23-2015) Abstract Talk: Temporal Regimes of State-Dependent Correlated Variability in the Macaque Ventrolateral Prefrontal Cortex, 16th Conference of Junior Neuroscientists of Tübingen (NeNa 2015): Communicating the Challenges of Science, Schramberg, Germany 18.
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Yang M, Logothetis NK and Eschenko O (October-10-2015) Abstract Talk: A gating role of mediodorsal thalamus for ripple-associated hippocampal-cortical information transfer, Federation of European Neuroscience Society Featured Regional Meeting (FFRM 2015), Thessaloniki, Greece.
Logothetis NK (October-8-2015) Keynote Lecture: NET-fMRI of Large-Scale Brain Networks: Mapping Dynamic Connectivity during Epochs of Synaptic and System Consolidation, Federation of European Neuroscience Society Featured Regional Meeting (FFRM 2015), Thessaloniki, Greece.
Logothetis NK (September-23-2015) Keynote Lecture: NET-fMRI of Large-Scale Brain Networks: Mapping Dynamic Connectivity in Epochs of Synaptic and System Consolidation, International Conference on System Level Approaches to Neural Engineering (ICSLANE 2015), Barcelona, Spain.
Logothetis NK (September-18-2015) Keynote Lecture: NET-fMRI of large-scale brain networks: mapping dynamic connectivity in epochs of synaptic and system consolidation, 19th Conference of the European Society for Cognitive Psychology (ESCOP 2015), Paphros, Cyprus.
Logothetis NK (June-23-2015) Invited Lecture: NET-fMRI of large-scale brain networks: mapping dynamic connectivity in epochs of synaptic and system consolidation, Brainy Days in Jerusalem: an Interdisciplinary Celebration, Jerusalem, Israel.
Zaldivar D, Logothetis NK and Goense J (June-2-2015) Abstract Talk: Laminar Differences in Neural Activity During Positive and Negative Bold Conditions, 23rd Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2015), Toronto, Canada(0357).
Logothetis NK (April-13-2015) Invited Lecture: The neural orchestration of memory consolidation, 23rd Colloque Médecine et Recherche of the Fondation IPSEN: Micro-, meso-, and macro-dynamics of the brain, Paris, France.
Logothetis NK (January-11-2015) Keynote Lecture: NET-fMRI of Large-Scale Brain Networks: Mapping Dynamic Connectivity during Epochs of Synaptic and System Consolidation, Alpine Brain Imaging Meeting (ABIM 2015), Champéry, Switzerland.
Logothetis NK (December-6-2014) Keynote Lecture: The neural orchestration of memory consolidation, International Symposium on Vision, Memory, Thought: How Cognition Emerges from Neural Network (VMAT 2014), Tokyo, Japan.
Papanikolaou A, Keliris GA, Lee S, Papageorgiou TD, Schiefer U, Logothetis NK and Smirnakis SM (November-19-2014) Abstract Talk: Organization of human area V5/MT+ and sensitivity to motion coherence after lesions of the primary visual cortex, 44th Annual Meeting of the Society for Neuroscience (Neuroscience 2014), Washington, DC, USA 772.07.
Besserve M, Schölkopf B and Logothetis NK (November-15-2014) Abstract Talk: Unsupervised identification of neural events in local field potentials, 44th Annual Meeting of the Society for Neuroscience (Neuroscience 2014), Washington, DC, USA 2.12.
Logothetis NK (October-4-2014) Invited Lecture: Mechanisms of action of invasive neurostimulation, 5th Belgian Brain Congress (BBC 2014), Ghent, Belgium.
Perrodin C, Petkov CI, Logothetis NK and Kayser C (June-13-2014) Abstract Talk: Auditory and audiovisual specificity for processing communication signals in the superior temporal lobe, 15th International Multisensory Research Forum (IMRF 2014), Amsterdam, The Netherlands 28.
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Last updated: Monday, 22.05.2017