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Prof. Dr. Nikos Logothetis

Address: Spemannstr. 38
72076 Tübingen
Room number: 121
Phone: +49 7071 601 651
Fax: +49 7071 601 652
E-Mail: nikos.logothetis

 

Picture of Logothetis, Nikos, Prof. Dr.

Nikos Logothetis

Position: Director  Unit: Logothetis

Research in this laboratory concentrates on the neural mechanisms of perception and object recognition. Although our basic research revolves around vision, a number of independent collaborators are also investigating the relationship between neural activity and perception using other sensory modalities. I firmly believe that such scientific questions require a multimodal methodological approach that integrates information obtained from single units with that derived from mass action potentials as well as from a number of activity-related, surrogate signals such as those monitored during noninvasive experiments. Parallel to our ongoing research, therefore, we are also working to develop methodologies that will permit us to study neural networks in the context of behavioral paradigms. We have already designed and implemented two high-field magnetic resonance imaging systems for functional, anatomical and spectroscopic imaging. The systems are endowed with all the necessary hard- and software to conduct simultaneous imaging and recordings, and they are being used to study the function, connectivity, and neurochemistry of the non-human primate brain. Furthermore, while continuing to exploit traditional neuroimaging in our experiments, we are also investigating the relationship of neural activity to the MR-measurable hemodynamic responses and experimenting with methods that do not rely on hemodynamic responses at all. In the context of the last-named project, a group of synthetic and coordination chemists in my laboratory are attempting to synthesize and evaluate MR-detectable smart probes that change magnetic properties as a function of the concentration of ions and molecules involved in neural signaling. Smart contrast agents, if designed and tested appropriately, promise to revolutionize invasive neuroimaging and would represent a quantum leap forward in signal-to-noise ratio, spatial detail and specificity, while affording unprecedented temporal resolution.
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Nikos K. Logothetis is director of the department “Physiology of Cognitive Processes” at the Max Planck Institute for Biological Cybernetics (MPIK), in Tübingen, Germany. He received a B.S. in mathematics from the University of Athens, a B.S. in biology from the University of Thessaloniki, and his Ph.D. in human neurobiology from the Ludwig-Maximilians University in Munich. In 1985 he moved to the Brain and Cognitive Sciences Department of M.I.T., where he initially worked as a postdoctoral fellow and later as Research Scientist. In 1990 he joined the faculty of the Division of Neuroscience at the Baylor College of Medicine. Seven years later he moved to the Max Planck Institute for Biological Cybernetics to continue his work on the physiological mechanisms underlying visual perception and object recognition.

In addition to visual cognition, his work at MPIC includes auditory perception and multisensory integration, as well as studies of plasticity and neuromodulation. Parallel to this ongoing research, a number of methods have been developed that permit the study of neural networks in the context of behavioral paradigms. Two high-field magnetic resonance imaging systems were designed and implemented for functional, anatomical and spectroscopic imaging. They permit simultaneous imaging and intracortical recordings and are being used to study the function, connectivity, and neurochemistry of the non-human primate brain, as well as the relationship of neural activity to the MR-measurable hemodynamic responses. Last but not least a group of synthetic and coordination chemists at MPIC are attempting to synthesize and evaluate MR-detectable smart probes that change magnetic properties as a function of the concentration of ions and molecules involved in neural signaling.

Since 1992 Nikos K. Logothetis has been Adjunct Professor of Neurobiology at the Salk Institute in San Diego, since 1995 Adjunct Professor of Ophthalmology at the Baylor College of Medicine, Houston, Associate of the Neurosciences Institute, San Diego, Senior Visiting Fellow in University College, London, Adjunct Professor in the Department of Cognitive and Neural Systems and of Cognitive and Neural Systems in the College of Arts and Sciences, both at the Boston University, Massachusetts, a  faculty member at the Victoria University of Manchester (VUM) in England, and Honorary Professor in the Department of Biology at the University of Tübingen.

Nikos K. Logothetis has been or continues to be a member of the Advisory Boards of McGovern Institute, M.I.T.; Brain and Cognitive Sciences, M.I.T., USA; POSIT Science Corporation, San Francisco, USA; IGPS, Freiburg, Germany; Centre of Excellence in Systems Neuroscience of the Academy of Finland, Helsinki, Finland; Brain Imaging Center, Frankfurt am Main, Germany; ICM-ADREC, Paris, France; Brain Center of the Hebrew University, Jerusalem, Israel, and in the Advisory Board of the Brain Research Center of the Weizmann Institute, Jerusalem, Israel.  He served as Receiving Editor for the European Journal of Neuroscience (EJN), Associate Editor for Trends in Cognitive Sciences (TICS), Neuron, Current Biology, Current Opinion Neurobiology, and is a regular reviewer for Nature, Nature Neuroscience, J Neuroscience, PNAS, Cerebral Cortex, Cerebral Blood Flow and Metabolism, Journal of Neurophysiology, Experimental Brain Research, and Vision Research. He is a member of the Society for Neuroscience, European Neuroscience Association, American Association for the Advancement of Science, Association for Research in Vision and Ophthalmology, New York Academy of Sciences, Society for Industrial and Applied Mathematics, American Mathematical Society, International Neuropsychological Society, and Mathematical Association of America.

Nikos K. Logothetis is member of the German Academy of Natural Scientists Leopoldina, of the Rodin Remediation Academy, Honorary Member of the American Academy of Arts and Sciences, and a foreign associate of the National Academy of Sciences of the United States. He is recipient of the DeBakey Award for Excellence in Science, the Golden Brain Award of the Minerva Foundation, the 2003 Louis-Jeantet Prize of Medicine, the 2004 Zülch-Price for Neuroscience, the 2007 IPSEN Prize for Neuronal Plasticity, and the 2008 Alden Spencer Award of Columbia University, New York.

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Posters (573):

Tolias AS, Augath M, Pauls J, Oeltermann A, Tehovnik EJ, Schiller PH and Logothetis NK (November-2003): Simultaneous electrical microstimulation and fMRI in the macaque, 33rd Annual Meeting of the Society for Neuroscience (Neuroscience 2003), New Orleans, LA, USA.
Fust A, Pauls J, Augath M, Oeltermann A, Murayama Y and Logothetis NK (November-2003): The influence of anaesthetic agents on spiking and subthreshold activity in visual cortex revealed by electrophysiology and high-resolution functional MRI, 33rd Annual Meeting of the Society for Neuroscience (Neuroscience 2003), New Orleans, LA, USA.
Shmuel A, Augath M, Oeltermann A, Pauls J and Logothetis NK (November-2003): The Negative BOLD Response in Monkey V1 is Associated with Decreases in Neuronal Activity, 33rd Annual Meeting of the Society for Neuroscience (Neuroscience 2003), New Orleans, LA, USA.
Nielsen K, Logothetis NK and Rainer G (November-2003): Visual discrimination strategies of monkey and human observers, 33rd Annual Meeting of the Society for Neuroscience (Neuroscience 2003), New Orleans, LA, USA.
Kourtzi Z, Tolias AS, Altmann CF, Augath M and Logothetis NK (October-2003): Integration of local features into global shapes: monkey and human fMRI studies, Third Annual Meeting of the Vision Sciences Society (VSS 2003), Sarasota, FL, USA, Journal of Vision, 3(9) 191.
Maier A, Logothetis NK and Leopold DA (September-2003): Competition and integration in monocular rivalry, 26th European Conference on Visual Perception, Paris, France, Perception, 32(ECVP Abstract Supplement) 115.
Wilke M, Leopold DA and Logothetis NK (September-2003): Flash-induced subjective disappearance of salient visual stimuli, 26th European Conference on Visual Perception, Paris, France, Perception, 32(ECVP Abstract Supplement) 137.
Juchem C, Merkle H, Logothetis NK and Pfeuffer J (September-2003): In vivo CSI of glutamate in Macaca mulatta brain, 20th Annual Scientific Meeting of the ESMRMB 2003, Rotterdam, Netherlands, Magnetic Resonance Materials in Physics, Biology and Medicine, 16(Supplement 7) 145-146.
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Pfeuffer J, Juchem C, Merkle H and Logothetis NK (July-15-2003): Proton MR Spectroscopy at 7 Tesla in the Macaque monkey, 11th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2003), Toronto, Canada.
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Pfeuffer J, Pauls J, Augath MA, Steudel T, Merkle H and Logothetis NK (July-13-2003): Functional MR imaging of the awake monkey in a novel vertical large-bore 7 Tesla setup, 11th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2003), Toronto, Canada.
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Shmuel A, Augath MA, Rounis E, Logothetis NK and Smirnakis SM (June-2003): Negative BOLD Response Ipsi-lateral to the Visual Stimulus: Origin Is Not Blood Stealing, Ninth Annual Meeting of the Organization for Human Brain Mapping (HBM 2003), New York, NY, USA, NeuroImage, 19(2 Supplement) e570-e571.
Shmuel A, Augath MA, Oeltermann A, Pauls J, Murayama Y and Logothetis NK (June-2003): The Negative BOLD Response in Monkey V1 Is Associated with Decreases in Neuronal Activity, Ninth Annual Meeting of the Organization for Human Brain Mapping (HBM 2003), New York, NY, USA, NeuroImage, 19(2 Supplement) e567-e568.
Nielsen K, Logothetis NK and Rainer G (February-2003): Visual discrimination strategies of monkey and human observers for simple geometric shapes, 6. Tübinger Wahrnehmungskonferenz (TWK 2003), Tübingen, Germany.
Pauls J and Logothetis NK (November-2002): Activity of inferior temporal (IT) neurons changes with task context: A comparison of classification and identification, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Krekelberg B, Augath M and Logothetis NK (November-2002): Biological motion processing in the macaque-fMRI, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Tolias AS, Siapas AG, Smirnakis SM and Logothetis NK (November-2002): Coding visual information at the level of populations of neurons, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Logothetis NK, Augath M and Oeltermann A (November-2002): Combined neurophysiology and fMRI in the awake monkey, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Sereno M, Augath M and Logothetis NK (November-2002): Cue-invariant 3-D shape representation in monkey cortex using fMRI, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Rainer G and Logothetis NK (November-2002): Effects of visual experience, contrast and color on neural responses in area V4 to natural images, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Wilke M, Leopold DA and Logothetis NK (November-2002): Flash suppression without interocular conflict, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Keliris GA, Smirnakis SM, Kourtzi Z, Tolias AS and Logothetis NK (November-2002): FMRI Correlates of Perceptual Filling-in in a Moving Random Dot Paradigm, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Kourtzi Z, Tolias AS, Augath M and Logothetis NK (November-2002): fMRI responses to visual shapes at different spatial scales, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Smirnakis SM, Brewer AA, Schmid M, Tolias AS, Augath M, Inhoffen W, Wandell BA and Logothetis NK (November-2002): Macaque visual cortex reorganisation after homonymous retinal scotoma probed by fMRI, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Schmid M, Smirnakis SM, Tolias AS, Augath M and Logothetis NK (November-2002): Mapping Macaque Visual Cortex Organization with BOLD and MION fMRI, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Maier A, Leopold DA and Logothetis NK (November-2002): Neural activity during stable perception of ambiguous displays in monkey visual cortex, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Sigala N and Logothetis NK (November-2002): Neural correlates of categorization in monkeys, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Ghazanfar AA, Pauls J, Leopold DA, Hauser MD and Logothetis NK (November-2002): Neural responses to species-specific vocalizations in the auditory association cortex of the awake behaving rhesus monkey, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Shmuel A, Augath M, Oeltermann A and Logothetis NK (November-2002): Sustained negative BOLD response in the monkey brain, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Tse PU, Smith MA, Augath MA, Trinath T, Logothetis NK and Movshon JA (November-2002): Using Glass Patterns and fMRI to identify areas that process global form in macaque visual cortex, Second Annual Meeting of the Vision Sciences Society (VSS 2002), Sarasota, FL, USA, Journal of Vision, 2(7) 285.
Leopold D, Augath M and Logothetis NK (November-2002): Visualizing global brain networks in the monkey using combined fMRI and electrophysiology, 32nd Annual Meeting of the Society for Neuroscience (Neuroscience 2002), Orlando, FL, USA.
Merkle H, Pfeuffer J and Logothetis NK (August-2002): 300 MHz RF coils for MR studies of Macaca mulatta brain at 7 Tesla, 19th Annual Scientific Meeting of the ESMRMB 2002, Cannes, France.
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Leopold DA, Bondar IV, O'Toole AJ and Logothetis NK (August-2002): Exploring face representation in humans and monkeys by using high-level aftereffects, 25th European Conference on Visual Perception, Glasgow, UK, Perception, 31(ECVP Abstract Supplement) 60.
Pfeuffer J, Merkle H and Logothetis NK (August-2002): Functional MR imaging of the monkey brain in a novel vertical large-bore 7 Tesla setup, 19th Annual Scientific Meeting of the ESMRMB 2002, Cannes, France.
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Juchem C, Augath MA, Merkle H, Logothetis NK and Pfeuffer J (August-2002): In vivo 1H Spectroscopy of the Caudate Nucleus in Macaca mulatta brain, 19th Annual Scientific Meeting of the ESMRMB 2002, Cannes, France.
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Nielsen K, Rainer G, Brucklacher V and Logothetis NK (August-2002): Studying the representation of natural images using behavioural reverse correlation, 25th European Conference on Visual Perception, Glasgow, UK, Perception, 31(ECVP Abstract Supplement) 134.
Bondar I, Leopold DA and Logothetis NK (July-2002): Prototype-referenced encoding of faces in monkeys, 3rd Forum of European Neuroscience (FENS 2002), Paris, France.
Prause B, Saleem KS, Pauls J, Augath M, Trinath T, Hashikawa T and Logothetis NK (May-21-2002): In Vivo MRI of Neuronal Connections in the Macaque Monkey, 10th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2002), Honolulu, HI, USA.
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Rainer G and Logothetis NK (May-2002): Correlates of visual learning in area V4, 5. Tübinger Wahrnehmungskonferenz (TWK 2002), Tübingen, Germany.
Haiss F, Leopold DA, Murayama Y and Logothetis NK (February-2002): Dynamics of brain state transitions during anesthetic induction in the monkey, 5. Tübinger Wahrnehmungskonferenz (TWK 2002), Tübingen, Germany.
Bondar IV, Leopold DA, Pauls JM and Logothetis NK (February-2002): Investigation of face representation in monkeys using adaptational aftereffects, 5. Tübinger Wahrnehmungskonferenz (TWK 2002), Tübingen, Germany.
Maier A, Wilke M, Leopold DA and Logothetis NK (February-2002): Parallel perception of multiple visually bistable patterns, 5. Tübinger Wahrnehmungskonferenz (TWK 2002), Tübingen, Germany.
Wilke M, Maier A, Leopold DA and Logothetis NK (February-2002): Periods of stimulus absence stabilize the perception of ambiguous patterns, 5. Tübinger Wahrnehmungskonferenz (TWK 2002), Tübingen, Germany.
Lee H, Rainer G and Logothetis NK (February-2002): Psychophysikalische Studien zur Lerninvarianz von Objekten, 5. Tübinger Wahrnehmungskonferenz (TWK 2002), Tübingen, Germany.
Tse PU, Sheinberg DL and Logothetis NK (December-2001): Spatial attention elongates both toward and away from an exogenous flash, First Annual Meeting of the Vision Sciences Society (VSS 2001), Sarasota, FL, USA, Journal of Vision, 1(3) 82.
Pauls J and Logothetis NK (November-2001): Classification versus identification: task context effects the responses of neurons in inferior temporal cortex, 31st Annual Meeting of the Society for Neuroscience (Neuroscience 2001), San Diego, CA, USA.
Leopold DA, Murayama Y and Logothetis NK (November-2001): Determinants of neural activity covariation in macaque visual cortex under different behavioral states, 31st Annual Meeting of the Society for Neuroscience (Neuroscience 2001), San Diego, CA, USA.
Kourtzi Z, Tolias AS, Prause BA, Augath M, Trinath T and Logothetis NK (November-2001): fMRI adaptation for visual forms in the monkey brain, 31st Annual Meeting of the Society for Neuroscience (Neuroscience 2001), San Diego, CA, USA.
Logothetis NK, Pauls J, Oeltermann A, Augath M and Trinath T (November-2001): In vivo study of connectivity with electrical microstimulation and fMRI, 31st Annual Meeting of the Society for Neuroscience (Neuroscience 2001), San Diego, CA, USA.
Saleem KS, Prause BA, Pauls J, Augath M, Trinath T, Hashikawa T and Logothetis NK (November-2001): Magnetic resonance imaging of neuronal connections in the macaque monkey, 31st Annual Meeting of the Society for Neuroscience (Neuroscience 2001), San Diego, CA, USA.
Kirschfeld K, Sigala N and Logothetis NK (November-2001): Natural images: a lingua franca for primates?, 31st Annual Meeting of the Society for Neuroscience (Neuroscience 2001), San Diego, CA, USA.
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Last updated: Monday, 22.05.2017