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Prof. Dr. Nikos Logothetis

Address: Spemannstr. 38
72076 Tübingen
Room number: 121
Phone: +49 7071 601 651
Fax: +49 7071 601 652
E-Mail: nikos.logothetis

 

Picture of Logothetis, Nikos, Prof. Dr.

Nikos Logothetis

Position: Director  Unit: Logothetis

Research in this laboratory concentrates on the neural mechanisms of perception and object recognition. Although our basic research revolves around vision, a number of independent collaborators are also investigating the relationship between neural activity and perception using other sensory modalities. I firmly believe that such scientific questions require a multimodal methodological approach that integrates information obtained from single units with that derived from mass action potentials as well as from a number of activity-related, surrogate signals such as those monitored during noninvasive experiments. Parallel to our ongoing research, therefore, we are also working to develop methodologies that will permit us to study neural networks in the context of behavioral paradigms. We have already designed and implemented two high-field magnetic resonance imaging systems for functional, anatomical and spectroscopic imaging. The systems are endowed with all the necessary hard- and software to conduct simultaneous imaging and recordings, and they are being used to study the function, connectivity, and neurochemistry of the non-human primate brain. Furthermore, while continuing to exploit traditional neuroimaging in our experiments, we are also investigating the relationship of neural activity to the MR-measurable hemodynamic responses and experimenting with methods that do not rely on hemodynamic responses at all. In the context of the last-named project, a group of synthetic and coordination chemists in my laboratory are attempting to synthesize and evaluate MR-detectable smart probes that change magnetic properties as a function of the concentration of ions and molecules involved in neural signaling. Smart contrast agents, if designed and tested appropriately, promise to revolutionize invasive neuroimaging and would represent a quantum leap forward in signal-to-noise ratio, spatial detail and specificity, while affording unprecedented temporal resolution.
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Nikos K. Logothetis is director of the department “Physiology of Cognitive Processes” at the Max Planck Institute for Biological Cybernetics (MPIK), in Tübingen, Germany. He received a B.S. in mathematics from the University of Athens, a B.S. in biology from the University of Thessaloniki, and his Ph.D. in human neurobiology from the Ludwig-Maximilians University in Munich. In 1985 he moved to the Brain and Cognitive Sciences Department of M.I.T., where he initially worked as a postdoctoral fellow and later as Research Scientist. In 1990 he joined the faculty of the Division of Neuroscience at the Baylor College of Medicine. Seven years later he moved to the Max Planck Institute for Biological Cybernetics to continue his work on the physiological mechanisms underlying visual perception and object recognition.

In addition to visual cognition, his work at MPIC includes auditory perception and multisensory integration, as well as studies of plasticity and neuromodulation. Parallel to this ongoing research, a number of methods have been developed that permit the study of neural networks in the context of behavioral paradigms. Two high-field magnetic resonance imaging systems were designed and implemented for functional, anatomical and spectroscopic imaging. They permit simultaneous imaging and intracortical recordings and are being used to study the function, connectivity, and neurochemistry of the non-human primate brain, as well as the relationship of neural activity to the MR-measurable hemodynamic responses. Last but not least a group of synthetic and coordination chemists at MPIC are attempting to synthesize and evaluate MR-detectable smart probes that change magnetic properties as a function of the concentration of ions and molecules involved in neural signaling.

Since 1992 Nikos K. Logothetis has been Adjunct Professor of Neurobiology at the Salk Institute in San Diego, since 1995 Adjunct Professor of Ophthalmology at the Baylor College of Medicine, Houston, Associate of the Neurosciences Institute, San Diego, Senior Visiting Fellow in University College, London, Adjunct Professor in the Department of Cognitive and Neural Systems and of Cognitive and Neural Systems in the College of Arts and Sciences, both at the Boston University, Massachusetts, a  faculty member at the Victoria University of Manchester (VUM) in England, and Honorary Professor in the Department of Biology at the University of Tübingen.

Nikos K. Logothetis has been or continues to be a member of the Advisory Boards of McGovern Institute, M.I.T.; Brain and Cognitive Sciences, M.I.T., USA; POSIT Science Corporation, San Francisco, USA; IGPS, Freiburg, Germany; Centre of Excellence in Systems Neuroscience of the Academy of Finland, Helsinki, Finland; Brain Imaging Center, Frankfurt am Main, Germany; ICM-ADREC, Paris, France; Brain Center of the Hebrew University, Jerusalem, Israel, and in the Advisory Board of the Brain Research Center of the Weizmann Institute, Jerusalem, Israel.  He served as Receiving Editor for the European Journal of Neuroscience (EJN), Associate Editor for Trends in Cognitive Sciences (TICS), Neuron, Current Biology, Current Opinion Neurobiology, and is a regular reviewer for Nature, Nature Neuroscience, J Neuroscience, PNAS, Cerebral Cortex, Cerebral Blood Flow and Metabolism, Journal of Neurophysiology, Experimental Brain Research, and Vision Research. He is a member of the Society for Neuroscience, European Neuroscience Association, American Association for the Advancement of Science, Association for Research in Vision and Ophthalmology, New York Academy of Sciences, Society for Industrial and Applied Mathematics, American Mathematical Society, International Neuropsychological Society, and Mathematical Association of America.

Nikos K. Logothetis is member of the German Academy of Natural Scientists Leopoldina, of the Rodin Remediation Academy, Honorary Member of the American Academy of Arts and Sciences, and a foreign associate of the National Academy of Sciences of the United States. He is recipient of the DeBakey Award for Excellence in Science, the Golden Brain Award of the Minerva Foundation, the 2003 Louis-Jeantet Prize of Medicine, the 2004 Zülch-Price for Neuroscience, the 2007 IPSEN Prize for Neuronal Plasticity, and the 2008 Alden Spencer Award of Columbia University, New York.

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Posters (569):

Dahl CD, Logothetis NK and Kayser C (November-2007): Functional organization of responses in the polysensory temporal region (STP) in the Macaque monkey, 37th Annual Meeting of the Society for Neuroscience (Neuroscience 2007), San Diego, CA, USA.
Remedios R, Logothetis NK and Kayser C (November-2007): Multisensory Integration in the Claustrum, 37th Annual Meeting of the Society for Neuroscience (Neuroscience 2007), San Diego, CA, USA.
Kayser C, Petkov CI, Augath M and Logothetis NK (November-2007): Multisensory interactions in auditory cortex, 37th Annual Meeting of the Society for Neuroscience (Neuroscience 2007), San Diego, CA, USA.
Berens P, Ecker AS, Keliris GA, Logothetis NK and Tolias AS (November-2007): On the spatial scale of the local field potential - orientation and ocularity tuning of the local field potential in the primary visual cortex of the macaque, 37th Annual Meeting of the Society for Neuroscience (Neuroscience 2007), San Diego, CA, USA.
Wang Z, Maier A, Logothetis NK, Leopold DA and Liang H (November-2007): Prestimulus activity in area MT predicts psychophysical performance in a bistable motion task, 37th Annual Meeting of the Society for Neuroscience (Neuroscience 2007), San Diego, CA, USA.
Ecker AS, Siapas AG, Hoenselaar A, Berens P, Keliris GA, Logothetis NK and Tolias AS (November-2007): Recording chronically from the same neurons in awake, behaving primates, 37th Annual Meeting of the Society for Neuroscience (Neuroscience 2007), San Diego, CA, USA.
Ku S-P, Goense J, Tolias AS and Logothetis NK (November-2007): Using SE-EPI to measure visual responses in temporal lobe of awake macaque at 7 Tesla, 37th Annual Meeting of the Society for Neuroscience (Neuroscience 2007), San Diego, CA, USA.
Zappe A-C, Goense JBM and Logothetis NK (November-2007): Very High Resolution Perfusion MRI of the Laminar Structure in Primate Visual Cortex, 37th Annual Meeting of the Society for Neuroscience (Neuroscience 2007), San Diego, CA, USA.
Petkov CI, Kayser C, Whittingstall K, Steudel T, Augath M and Logothetis NK (September-2007): A voice-area in the primate brain: Enhanced representation of the "voice" of conspecifics, International Symposium on Evolution of Emotional Communication (EEC 2007), Hannover, Germany.
Mamedov I, Angelovski G, Henig J, Mayer HA and Logothetis NK (September-2007): Azamacrocyclic Ca2+ Sensitive Contrast Agents for MR Imaging, AMI/SMI Joint Molecular Imaging Conference 2007, Providence, RI, USA.
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Ecker AS, Berens P, Bethge M, Logothetis NK and Tolias AS (September-2007): Studying the effects of noise correlations on population coding using a sampling method, Neural Coding, Computation and Dynamics (NCCD 07), Hossegor, France.
Dhingra K, Fousková P, Angelovski G, Meier ME, Logothetis NK and Tóth É (September-2007): Synthesis and Calcium Dependent Relaxation Studies of new Bismacrocyclic Ligands, AMI/SMI Joint Molecular Imaging Conference 2007, Providence, RI, USA.
Mishra A, Fousková P, Balogh E, Angelovski G, Logothetis NK and Tóth É (September-2007): Synthesis and Relaxation Properties of Three Novel Bis-macrocycles: Attempt towards Calcium Sensitive MRI Contrast Agents, AMI/SMI Joint Molecular Imaging Conference 2007, Providence, RI, USA.
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Dahl CD, Wallraven C, Bülthoff HH and Logothetis NK (August-2007): Conspecific and human face processing in monkeys (Macaca mulatta): An eye movement investigation, 30th European Conference on Visual Perception, Arezzo, Italy, Perception, 36(ECVP Abstract Supplement) 146-147.
Alanis GRS, Logothetis NK and Rainer G (August-2007): Reading out the perceptual boundary between human and monkey face categories from the inferior temporal cortex of the macaque monkey, 30th European Conference on Visual Perception, Arezzo, Italy, Perception, 36(ECVP Abstract Supplement) 218-219.
Liebe S, Logothetis NK and Rainer G (July-2007): Enhanced Selectivity for Natural Image Color in V4 but Not PF, 10th Tübinger Wahrnehmungskonferenz (TWK 2007), Tübingen, Germany.
Petkov CI, Kayser C, Augath M, Steudel T and Logothetis NK (July-2007): Functional imaging of organization and specialization in the monkey auditory cortex, 2nd International Conference on Auditory Cortex 2006: The Listening Brain, Grantham, UK, Hearing Research, 229(1-2) 239-240.
Chakladar S, Logothetis NK and Petkov C (July-2007): Morphing macaque vocalizations for behavioral and neurophysiological study, Magnetresonanzzentrum Symposium 2007, Tübingen, Germany.
Kayser C, Petkov C and Logothetis NK (July-2007): Multisensory Interactions in Auditory Cortex, 10th Tübinger Wahrnehmungskonferenz (TWK 2007), Tübingen, Germany.
Remedios R, Logothetis NN and Kayser C (July-2007): Multisensory Interactions in the Claustrum, 10th Tübinger Wahrnehmungskonferenz (TWK 2007), Tübingen, Germany.
Fischer E, Liebe S, Logothetis NK and Rainer G (July-2007): The Importance of Color in Object Recognition, 10th Tübinger Wahrnehmungskonferenz (TWK 2007), Tübingen, Germany.
Sigala R, Veit J, Logothetis NK and Rainer G (July-2007): Using the Local Field Potential (LFP) Recorded from the Inferior-Temporal Cortex of a Macaque Monkey to Study Species-Dependent (Monkey/human) Face Processing, 10th Tübinger Wahrnehmungskonferenz (TWK 2007), Tübingen, Germany.
Shmuel A, Raddatz G, Chaimow D, Logothetis NK, Ugurbil K and Yacoub E (June-2007): Origin of ‘decoding’ signals in the visual cortex: gray matter or macroscopic blood vessels?, 13th Annual Meeting of the Organization for Human Brain Mapping (HBM 2007), Chicago, IL, USA, NeuroImage, 36(Supplement 1) S97.
Shmuel A, Augath M, Oeltermann A and Logothetis NK (June-2007): Spontaneous fluctuations in functional MRI signal reflect fluctuations in the underlying local neuronal activity, 13th Annual Meeting of the Organization for Human Brain Mapping (HBM 2007), Chicago, IL, USA, NeuroImage, 36(Supplement 1) S58.
Canals S, Beyerlein M, Keller AL, Murayama Y and Logothetis NK (May-23-2007): In vivo brain connectivity: optimization of manganese enhanced MRI for neuronal tract tracing, 2007 Joint Annual Meeting ISMRM-ESMRMB, Berlin, Germany.
Goense JBM, Ku S-P, Merkle H, Tolias AS and Logothetis NK (May-23-2007): Spin-echo fMRI of the temporal lobe in awake, behaving monkeys at 7T, 2007 Joint Annual Meeting ISMRM-ESMRMB, Berlin, Germany.
Mangia S, Tkac I, Logothetis NK, Van de Moortele P-F, Gruetter R and Ugurbil K (May-21-2007): Dynamics of Lactate Concentration and BOLD Effect Upon Repeated Identical Visual Stimuli, 2007 Joint Annual Meeting ISMRM-ESMRMB, Berlin, Germany.
Ecker AS, Berens P, Keliris GA, Logothetis NK and Tolias AS (April-2007): A Data Management System for Electrophysiological Data Analysis, 7th Meeting of the German Neuroscience Society, 31st Göttingen Neurobiology Conference, Göttingen, Germany, Neuroforum, 13(Supplement) 1222.
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Kayser C, Petkov C, Augath M and Logothetis NK (April-2007): Cross-modal integration of sensory information in auditory cortex, 7th Meeting of the German Neuroscience Society, 31st Göttingen Neurobiology Conference, Göttingen, Germany, Neuroforum, 13(Supplement) 835.
Canals S, Beyerlein M, Keller AL, Murayama Y and Logothetis NK (April-2007): In vivo brain connectivity: optimization of manganese enhanced MRI for neuronal tract tracing, 7th Meeting of the German Neuroscience Society, 31st Göttingen Neurobiology Conference, Göttingen, Germany, Neuroforum, 13(Supplement) 1221.
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Rauch A, Zhang X, Rainer G and Logothetis NK (April-2007): Increased acetylcholine release in prefrontal cortex of monkey during a cognitive task, 7th Meeting of the German Neuroscience Society, 31st Göttingen Neurobiology Conference, Göttingen, Germany, Neuroforum, 13(Supplement) 539.
Remedios R, Logothetis NK and Kayser C (April-2007): Multiple multi-sensory networks involve the claustrum, 7th Meeting of the German Neuroscience Society, 31st Göttingen Neurobiology Conference, Göttingen, Germany, Neuroforum, 13(Supplement) 897.
Sigala A. GR, Nielsen K, Logothetis NK and Rainer G (April-2007): Neural encoding of species dependent face-categories in the macaque temporal cortex, 7th Meeting of the German Neuroscience Society, 31st Göttingen Neurobiology Conference, Göttingen, Germany, Neuroforum, 13(Supplement) 767.
Berens P, Keliris GA, Ecker AS, Logothetis NK and Tolias AS (April-2007): Orientation tuning of the local field potential and multi-unit activity in the primary visual cortex of the macaque, 7th Meeting of the German Neuroscience Society, 31st Göttingen Neurobiology Conference, Göttingen, Germany, Neuroforum, 13(Supplement) 735.
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Schmid M, Augath M, Logothetis NK and Smirnakis S (April-2007): Retinotopic activation of macaque area V2 without input from primary visual cortex, 7th Meeting of the German Neuroscience Society, 31st Göttingen Neurobiology Conference, Göttingen, Germany, Neuroforum, 13(Supplement) 737.
Liebe S, Logothetis NK and Rainer G (April-2007): The role of color in natural images to recognition performance and neural activity in extrastriate and prefrontal cortex, 7th Meeting of the German Neuroscience Society, 31st Göttingen Neurobiology Conference, Göttingen, Germany, Neuroforum, 13(Supplement) 766.
Beed P, Keller AL, Groso A, Stampanoni M, Logothetis NK and Weber B (April-2007): Topological tree-analysis of the microvascular system in macaque visual cortex, 7th Meeting of the German Neuroscience Society, 31st Göttingen Neurobiology Conference, Göttingen, Germany, Neuroforum, 13(Supplement) 736.
Ku S-P, Goense J, Tolias A and Logothetis NK (April-2007): Using SE-EPI to Measure Visual Responses in the Awake Macaque at 7 Tesla, 7th Meeting of the German Neuroscience Society, 31st Göttingen Neurobiology Conference, Göttingen, Germany, Neuroforum, 13(Supplement) 765.
Bartels A, Moutoussis K, Maugath , Zeki S and Logothetis N (March-2007): Mapping responses to natural stimuli in the primate brain: visual flow, retinotopy and tonotopy, V. Workshop of the International School on Magnetic Resonance and Brain Function (ISMRBF 2007), Erice, Italy.
Canals S and Logothetis NK (December-2006): MRI of Neuronal Connections, ENI-NET Christmas Meeting 2006, Sevilla, Spain.
Liang H, Wang X, Wang Z, Logothetis NK, Leopold DA and Maier A (November-2006): A comparison of local field potentials and spiking activity to predict perceptual report during bistable visual stimulation, 2nd Annual Conference on Computational Cognitive Neuroscience (CCNC 2006), Houston, TX, USA.
Wang Z, Maier A, Logothetis NK, Leopold DA and Liang H (November-2006): Neural population activity in area MT improves determination of perceptual states, 2nd Annual Conference on Computational Cognitive Neuroscience (CCNC 2006), Houston, TX, USA.
Ghazanfar AA, Chandrasekaran CF and Logothetis NK (October-13-2006): Coherence in Auditory Cortical Activity is Modulated by Face/Voice Integration in Rhesus Monkeys, Tucker-Davis Symposium on Advances and Perspectives in Auditory Neurophysiology (APAN IV), Atlanta, GA, USA.
Petkov C, Kayser C, Augath M, Steudel T and Logothetis N (October-13-2006): Organization and specialization of the monkey auditory cortex revealed with MR imaging, Tucker-Davis Symposium on Advances and Perspectives in Auditory Neurophysiology (APAN IV), Atlanta, GA, USA.
Chandrasekaran CF, van Dinther R, Patterson RD, Logothetis NK and Ghazanfar AA (October-13-2006): Representation of Formants & Fundamental Frequencies of Coo Calls in Rhesus Monkey Auditory Cortex, Tucker-Davis Symposium on Advances and Perspectives in Auditory Neurophysiology (APAN IV), Atlanta, GA, USA.
Liang H, Wang X, Wang Z, Logothetis NK, Leopold DA and Maier AV (October-2006): A comparison of local field potentials and spiking activity to predict perceptual report during bistable visual stimulation, 36th Annual Meeting of the Society for Neuroscience (Neuroscience 2006), Atlanta, GA, USA.
Hoffman KL, Gothard KM, Schmid MC and Logothetis NK (October-2006): BOLD responses to facial expressions and gaze direction in distinct amygdala subsystems of the macaque, 36th Annual Meeting of the Society for Neuroscience (Neuroscience 2006), Atlanta, GA, USA.
Ghazanfar AA, Chandrasekaran CF and Logothetis NK (October-2006): Coherence in auditory cortical activity is modulated by face/voice integration in rhesus monkeys, 36th Annual Meeting of the Society for Neuroscience (Neuroscience 2006), Atlanta, GA, USA.
Liebe S, Logothetis NK and Rainer G (October-2006): Contribution of color in natural images to recognition performance and neural activity in extrastriate and prefrontal cortex, 36th Annual Meeting of the Society for Neuroscience (Neuroscience 2006), Atlanta, GA, USA.
Petkov C, Kayser C, Augath M, Steudel T and Logothetis NK (October-2006): Functional imaging of organization and specialization in the monkey auditory cortex, 36th Annual Meeting of the Society for Neuroscience (Neuroscience 2006), Atlanta, GA, USA.
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Last updated: Monday, 22.05.2017