Contact

Dr. phil. Gisela Hagberg

Address: Spemannstr. 41
72076 Tübingen
Room number: 3.B.09
Phone: +49 7071 601 1648
Fax: +49 7071 601 652
E-Mail: gisela.hagberg

 

Picture of Hagberg, Gisela, Dr. phil.

Gisela Hagberg

Position: Guest Scientist  Unit: Scheffler

Clinical studies at Ultrahigh Magnetic Field strengths (UHF):

a window into Brain Microstructure

The advent of ultrahigh magnetic field strengths has boosted the field of neuroanatomy through the remarkable high level of detail that can be achieved in vivo. Fine-grained variations in MR contrast is linked with the underlying neurobiology and can be used to map brain tissue microstructure related to neuropathology as well as cyto- and myeloarchitecture. The advent of UHF thus opens up new possibilities to characterize healthy tissue, and investigate disease-related alterations of brain microstructure, eventually bringing in vivo histology with clinical relevance within reach.

Yet, with increasing field strength, methodological challenges in terms of increased inhomogeneity of the static field and the transmit field arise. Therefore, in order to achieve a high reproducibility in vivo, such factors need to be addressed

You'll find out more about on-going clinical projects here.

A core of quantitative MRI tools

for clinical and neuroscientific in vivo research at 9.4T has been established. Besides mapping of the transmit field, necessary to correct for the strong inhomogeneity, they consist of MP2RAGE-based mapping of the longitudinal relaxation (T1; R1) with isotropic voxel-sizes of 800µm down to 300µm; a multi echo 3D GRE sequence; with voxel-sizes of 375x375x800µm down to an isotropic voxel size of 400µm mainly for mapping the effective transverse relaxation (T2*; R2*), but that can also be used for quantitative susceptibility mapping (QSM); and a high-resolution acquisition weighted, single-echo 3D GRE sequence; with voxel-sizes down to 113x118x600µm used for QSM.

The whole protocol has a total duration of 45min and is therefore suited for clinical examinations of patients using a multi-modal imaging approach but without too harsh constraints on patient compliance. For validation purposes, this core of sequences has been complemented with single slice inversion-recovery mapping of T1 using EPI, and CPMG based mapping of T2, with an echo train consisting of 32 echoes and a minimum inter-echo time of 9ms, without exceeding SAR limits.

These protocols have been used to elucidate amongst other age-depndent variation in healthy subjects, the anatomical detail of the superior colliculus, beta-amyloid plaques in Alzheimer's and in post-mortem tissue.

The severe inhomogeneity of the transmit field poses a limit for quantitative studies at 9.4T. We found that this factor not only affects the MR signal excitation, but also impacts inversion efficiency, despite the use of adiabatic pulses. Such pulses are generally assumed to be immune to variations in B1, but through Bloch simulations and experiments we could confirm studies from the early ’90 demonstrating the vulnerability of that assumption (Hagberg et al., 2017). These findings further led us to propose an efficient correction for T1 (R1) mapping at 9.4T that tackles this issue and yields a high in vivo test-retest variability (< 1%) and low coefficient-of-variation (CoV<3% across 25 subjects at the level of extended regions-of-interest). Consistent with previous studies, we found that the primary sensory and motor areas had the greatest quantitative R1 values, in line with their greater myelin content with respect to other brain areas, and observed that the quantitative MRI parameters measured at 9.4T have a greater dynamic range than at 3T (Fig. 1). Nevertheless we could observe that the voxel wise CoV reached levels beyond 15% in grey matter regions, being several fold higher than in white matter voxels. This is interesting in view of the difficulty to detect myelin-related signals outside the white matter at 3T (Groeschel et al., 2016). Upon closer scrutiny we found that this effect derives from age-related variation in R1. The observed dynamics of MR-parameters across the human life-span could be explained in a model that takes into account decreasing grey matter volume fractions, increased iron levels and increased myelination of the cortical fibers with age (Fig. 2 and Hagberg et al., 2017b).

With further advancing age, several changes of the brain microstructure occur that may impact quantitative MRI measures. With age, the likelihood of presenting β-amyloid deposits increases, with prevalence peaking at age 70, even in a cognitively healthy population (Jack et al., 2017). In patient populations showing mild cognitive impairment, early identification of the presence of such deposits is essential since patients without them have a different clinical course towards non-Alzheimer dementia. Recently we found that QSM of post mortem samples can detect single β-amyloid plaques in Alzheimer’s at 14.1T, but only when voxel-sizes (37-50µm) on the order of the size of single plaques were employed (Fig. 3 and Tuzzi et al., 2016; 2017). This finding poses important questions regarding the best imaging protocols to use for in vivo MRI and the resolution necessary to answer clinical questions at UHF, since pathology–related effects of β-amyloid can be detected at high field but with coarser sampling (van Rooden et al., 2016).

A particularly challenging area for MRI research are the function and the anatomy of the deep brain nuclei located in the midbrain, characterized by a limited available signal-to-noise-ratio and a strong variation in background magnetic susceptibility. The superior colliculus (SC) is one of these brain nuclei and is a layered structure which serves as a gateway for several sensory modalities. Up-to-date, the layering pattern could only be identified in histology, or in vivo by functional challenge. We recently showed that layer specific fMRI activations of the superior colliculus (SC) can be detected at 9.4T (Loureiro 2017a). More recently (Loureiro 2016; 2017b) we found that the combined use of several quantitative MRI parameters provides a mean to study layer specific anatomy of the SC in vivo with features that are sensitive to the local microstructure that are reproducible across subjects. Moreover we observed that the combined use of several MRI parameters enabled identification of several anatomical structures within the midbrain areas (Fig. 4). Along with these measurements we employed MRI of post mortem samples at 14.1T and polarized light microscopy imaging to validate our observations regarding detectability of white matter fascicles in the brain stem. We are currently pursuing research activities in this direction with the aim to pin-point the source behind the obtained quantitative MRI measures and have extended our focus to include signal variations within and beyond the cortical rim in the occipital cortex (Fig. 5).

 

 

 

EDUCATION
1985-1988    Institute of technology, Lund (LTH), Sweden
1988-1990    Institute of technology, Lausanne (EPFL), Switzerland. Engineering project: 2D Nuclear Overhauser Effects (G. Bodenhausen)
1990 MSc in Engineering physics, EPFL and LTH. Thesis: Measurement of esophagal tumor depth by Laser-Induced Fluorescence” (A.Châtelain)
1990-1993    PhD trainee, University of Basel, Switzerland
1993 PhD in Biophysics, University of Basel, Switzerland. Thesis: Metabolism of the human brain investigated by 1H-MRS (J. Seelig)
2007 Medical Physics Specialization, University “La Sapienza”, Rome, Italy. Thesis: Detection of epileptogenic foci by neuronal current MRI (B. Maraviglia)


POSITIONS HELD at MPI
2010-2012  Post-doctoral Fellow, Logothetis Group, MPI for Biological Cybernetics, Tübingen, Germany
2012-current:  Research Scientist/Project leader, Scheffler Group, MPI for Biological Cybernetics  and University hospital Tübingen, Germany

 

VARIA
Scientific publications
68articles in peer-reviewed journals, co-author of 5 book-chapters, h-index:26 ; (see: http://www.researcherid.com/rid/A-2134-2010 ); i10: 52 (see Google Scholar)
Teaching activities
University of Tübingen, Germany;  ECM continuing education in medicine: BHC - Rome, Fondazione Santa Lucia – Rome; Lecturer Universita’ Tor Vergata, Co-supervisor of five Msc, one Medical Physics Specialization thesis and four PhD theses.
Approved Grants
Italian Ministry of Health: RF00.97.; RF00.99; RF05.103; University Tübingen CIN/Pool 2012-11; EU-LAC 2017
Patents
US Patent 7430313: Methods using recurrence quantification analysis to analyze and generate images. Zbilut JP, Sirabella P, Bianciardi M, Hagberg G, Colosimo A,Giuliani A.
Brevetto RM 00 A 000160, 31.3.2000: Method and equipment for generation of quantitative T2* maps for production of Magnetic resonance images in real-time GE Hagberg, S Posse, JN Sanes.
Invited talks
Karolinska Institute - Stockholm, CNR - Genova, International School on Magnetic Resonance and Brain Function – Erice, Strasbourg, France, Radboud University, Nijmegen, The Netherlands; Workshops and congresses of AIFM; ISMRM; EFOMP
On-call referee
American journal of Neuroradiology, Journal of Neurochemistry, Magnetic Resonance in Medicine, Medical Physics, Nature Medicine, NMR in Biomedicine, Neuroimage, Neuroradiology, Plos oNE, Abstract review: ISMRM 2006, 2009, 2012-2014; 2016 Brain PET, 2007, 2009, 2011, 2014
Memberships, organization of Congresses and Workshops
Italian Association for Medical Physics (AIFM, since 2005).  Board member organizing and scientific committees: Italian Federation of Radiation Research (FIRR) 2009, 2011; AIFM: 2011, 2013; ISMRM/AIFM/EFOMP: 2010

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Show abstracts

Articles (16):

Pavlova MA, Erb M, Hagberg GE, Loureiro J, Sokolov AN and Scheffler K (November-2017) "Wrong Way Up": Temporal and Spatial Dynamics of the Networks for Body Motion Processing at 9.4 T Cerebral Cortex 27(11) 5318–5330.
Loureiro JR, Hagberg GE, Ethofer T, Erb M, Bause J, Ehses P, Scheffler K and Himmelbach M (January-2017) Depth-dependence of visual signals in the human superior colliculus at 9.4 T Human Brain Mapping 38(1) 574–587.
Hagberg GE, Bause J, Ethofer T, Ehses P, Dresler T, Herbert C, Pohmann R, Shajan G, Fallgatter A, Pavlova MA and Scheffler K (January-2017) Whole brain MP2RAGE-based mapping of the longitudinal relaxation time at 9.4T NeuroImage 144(Part A) 203–216.
Groeschel S, Hagberg GE, Schultz T, Balla DZ, Klose U, Hauser T-K, Nägele T, Bieri O, Prasloski T, MacKay AL, Krägeloh-Mann I and Scheffler K (November-2016) Assessing White Matter Microstructure in Brain Regions with Different Myelin Architecture Using MRI PLoS ONE 11(11) 1-23.
Bisdas S, Chadzynski GL, Braun C, Schittenhelm J, Skardelly M, Hagberg GE, Ethofer T, Pohmann R, Shajan G, Engelmann J, Tabatabai G, Ziemann U, Ernemann U and Scheffler K (October-2016) MR spectroscopy for in vivo assessment of the oncometabolite 2-hydroxyglutarate and its effects on cellular metabolism in human brain gliomas at 9.4T Journal of Magnetic Resonance Imaging 44(4) 823–833.
Di Pietro G, Capuani S, Manenti G, Vinicola V, Fusco A, Baldi J, Scimeca M, Hagberg G, Bozzali M, Simonetti G and Tarantino U (March-2016) Bone Marrow Lipid Profiles from Peripheral Skeleton as Potential Biomarkers for Osteoporosis: A 1H-MR Spectroscopy Study Academic Radiology 23(3) 273–283.
Balla DZ, Sanchez-Panchuelo RM, Wharton SJ, Hagberg GE, Scheffler K, Francis ST and Bowtell R (October-2014) Functional quantitative susceptibility mapping (fQSM) NeuroImage 100 112–124.
Kadjane P, Platas-Iglesias C, Boehm-Sturm P, Truffault V, Hagberg GE, Hoehn M, Logothetis NK and Angelovski G (June-2014) Dual-Frequency Calcium-Responsive MRI Agents Chemistry: A European Journal 20(24) 7351–7362.
Angelovski G, Gottschalk S, Milošević M, Engelmann J, Hagberg GE, Kadjane P, Andjus P and Logothetis NK (May-2014) Investigation of a Calcium-Responsive Contrast Agent in Cellular Model Systems: Feasibility for Use as a Smart Molecular Probe in Functional MRI ACS Chemical Neuroscience 5(5) 360–369.
Hagberg G, Mamedov I, Power A, Beyerlein M, Merkle H, Kiselev VG, Dhingra K, Kubìček V, Angelovski G and Logothetis NK (January-2014) Diffusion properties of conventional and calcium-sensitive MRI contrast agents in the rat cerebral cortex Contrast Media & Molecular Imaging 9(1) 71–82.
Hagberg GE and Scheffler K (November-2013) Effect of r1 and r2 relaxivity of gadolinium-based contrast agents on the T1-weighted MR signal at increasing magnetic field strengths Contrast Media & Molecular Imaging 8(6) 456–465.
Placidi MP, Botta M, Kálmán FK, Hagberg GE, Baranyai Z, Krenzer A, Rogerson AK, Tóth I, Logothetis NK and Angelovski G (August-2013) Aryl-Phosphonate Lanthanide Complexes and Their Fluorinated Derivatives: Investigation of Their Unusual Relaxometric Behavior and Potential Application as Dual Frequency 1H/19F MRI Probes Chemistry - A European Journal 19(35) 11644–11660.
Pohmann R, Shajan G, Hoffmann J, Budde J, Hagberg G, Bieri O, Bisdas S, Ernemann U, Weigel M, Ehses P, Hennig J, Chadzynski G and Scheffler K (April-2013) Imaging and Spectroscopy at 9.4 Tesla: First Results on Patients and Volunteers MAGNETOM Flash 2013(2) 58-67.
Keliris A, Mamedov I, Hagberg GE, Logothetis NK, Scheffler K and Engelmann J (September-2012) A smart 19F and 1H MRI probe with self-immolative linker as a versatile tool for detection of enzymes Contrast Media & Molecular Imaging 7(5) 478–483.
Hagberg GE, Bianciardi M, Brainovich V, Cassara AN and Maraviglia B (February-2012) Phase stability in fMRI time series: Effect of noise regression, off-resonance correction and spatial filtering techniques NeuroImage 59(4) 3748–3761.
Hagberg G, Gefvert O, Bergström M, Wieselgren I-M, Lindström L, Wiesel F-A and Långström B (June-1998) N-[11C]Methylspiperone PET, in contrast to [11C]raclopride, fails to detect D2 receptor occupancy by an atypical neuroleptic Psychiatry Research: Neuroimaging 82(3) 147–160.

Conference papers (1):

Bianciardi M, Sirabella P, Hagberg G, Giuliani A, Zbilut JP and Colosimo A (September-2004) Analyzing Spatial Distributions of FMRI "Bold" Signals by RQA Variables, International Meeting Complexity in the living: a problem-oriented approach, Istituto Superiore di Sanità, Roma, Italy, 238-243, Series: Rapporti ISTISAN ; 05/20.

Contributions to books (2):

Garreffa G, Hagberg G and Indovina L: Physics of Hybrid Imaging, 3-12. In: PET-CT and PET-MRI in Neurology, (Ed) A. Ciarmiello, Springer, Cham, Switzerland, (2016).
Hagberg GE and Tuzzi E: Phase Variations in fMRI Time Series Analysis: Friend or Foe?, 81-113. In: Advanced Brain Neuroimaging Topics in Health and Disease: Methods and Applications, (Ed) T.D. Papageorgiou, InTech, Rijeka, Croatia, (May-2014).

Posters (26):

Pavlova M, Erb M, Hagberg G, Loureiro J, Sokolov AN and Scheffler K (November-15-2017): Spatial and temporal dynamics of the networks for body motion processing, 47th Annual Meeting of the Society for Neuroscience (Neuroscience 2017), Washington, DC, USA.
Cassara A, Neufeld E, Hagberg G, Guidon M, Scheffler K and Kuster N (April-27-2017): Peripheral Nerve Stimulation in MRI: Insights from a three level analysis and coupled EM-electrophysiological simulations in neuro-functionalized human models, 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017), Honolulu, HI, USA.
Hagberg G, Bause J, Ethofer T, Ehses P, Dresler T, Herbert C, Pohmann R, Shajan G, Fallgatter A, Pavlova M and Scheffler K (April-26-2017): Factors influencing the detection of age-dependent variations of cortical myelin by MP2RAGE at 9.4T, 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017), Honolulu, HI, USA.
Loureiro J, Hagberg G, Tuzzi E, Pohmann R, Schickardt Z, Himmelbach M, Ethofer T, Valverde M, Grodd W and Scheffler K (April-24-2017): Biological underpinnings of different MR contrasts in the human midbrain using quantitative structural MR imaging at 9.4T: Validation with 14T ex-vivo measurements and PLI, 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017), Honolulu, HI, USA.
Hagberg G, Keliris A, Srinivas M, Schulz H, Engelmann J, Schmehl J, Bantleon R, Mannheim J, Fuchs K, Pichler B, van der Linden A and Scheffler K (April-6-2017): 19F MRI-based detection of human mesenchymal stem cells (hMSC) labelled with fluorinated-PLGA nanoparticles, 12th Annual Meeting of the European Society for Molecular Imaging (EMIM 2017), Köln, Germany.
Pavlova M, Erb M, Hagberg G and Scheffler K (November-13-2016): Body motion presented upright and upside-down: Human ultra high field 9.4T fMRI, 46th Annual Meeting of the Society for Neuroscience (Neuroscience 2016), San Diego, CA, USA.
Pavlova MA, Erb M, Hagberg G, Sokolov A and Scheffler K (September-1-2016): Biological motion presented with upright and inverted display orientation: Human ultra high field 9.4 T fMRI, 39th European Conference on Visual Perception (ECVP 2016), Barcelona, Spain, Perception, 45(ECVP Abstract Supplement) 294-295.
Pavlova M, Erb M, Hagberg G, Loureiro J and Scheffler K (June-29-2016): Body motion presented upside-down: Human ultra-high field 9.4T fMRI, 22nd Annual Meeting of the Organization for Human Brain Mapping (OHBM 2016), Geneva, Switzerland.
Martin P, Hagberg G, Loureiro J, Bause J, Erb M, Lerche H, Scheffler K and Focke N (January-15-2016): Strukturelle Hochfeld-MRT-Bildgebung bei Epilepsie, Forschungskolloquium 2016 der Medizinischen Fakultät, Tübingen, Germany.
Loureiro JRA, Hagberg G, Ethofer T, Erb M, Scheffler K and Himmelbach M (October-19-2015): Depth-dependence of visual signals in the human superior colliculus: Comparison between 3T and 9.4T, 45th Annual Meeting of the Society for Neuroscience (Neuroscience 2015), Chicago, IL, USA.
Chadzynski G, Hagberg GE, Bause J, Shajan G, Bisdas S, Pohmann R, Engelmann J and Scheffler K (March-20-2015): Assessment of human brain tumors with proton magnetic resonance spectroscopic imaging at 9.4 Tesla, 10th Annual Meeting of the European Society for Molecular Imaging (EMIM 2015), Tübingen, Germany.
Hagberg GE, Keliris A, Srinivas M, Schulz H, Engelmann J, Schmehl J, Bantleon R and Scheffler K (March-19-2015): Characterization and MRI detection of 19F-PLGA labelled human mesenchymal stem cells, 10th Annual Meeting of the European Society for Molecular Imaging (EMIM 2015), Tübingen, Germany.
Chadzynski G, Bause J, Hagberg GE, Shajan G, Pohmann R, Engelmann J and Scheffler K (March-19-2015): Free induction decay proton magnetic resonance spectroscopic imaging in the healthy human brain at 9.4 Tesla: initial results, 10th Annual Meeting of the European Society for Molecular Imaging (EMIM 2015), Tübingen, Germany.
Keliris A, Engelmann J, Hagberg GE and Scheffler K (March-19-2015): Self-assembling peptide based system for detection of enzymatic activity by means of MRI, 10th Annual Meeting of the European Society for Molecular Imaging (EMIM 2015), Tübingen, Germany.
Sánchez-Castañeda C, Hagberg G, Squitieri F and Sabatini U (September-2014): Progressive Iron Accumulation In Huntington Disease Basal Ganglia: A Longitudinal Study, European Huntington’s Disease Network 8th Plenary Meeting, Barcelona, Spain, Journal of Neurology, Neurosurgery & Psychiatry, 85(Suppelment 1) A37-A38.
Hagberg GE, Martirosian P, Bause J, Shajan G, Klose U and Scheffler K (April-25-2013): Time-Of-Flight Angiography in Humans at 9.4T, 21st Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT, USA.
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Hagberg GE, Keliris A, Mamedov I, Placidi M, Merkle H, Logothetis NK and Scheffler K (April-23-2013): 19F-Lanthanide Complexes: T1 - and T2 - Dependent Signal Gain Using Gradient Echoes, 21st Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT, USA.
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Chadzynski G, Bisdas S, Hagberg G, Pohmann R, Shajan G, Kolb R, Klose U and Scheffler K (April-23-2013): First Proton CSI of a Human Brain Tumor at 9.4T, 21st Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT, USA.
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Hagberg GE, Mamedov I, Power A, Beyerlein M, Merckle H, Dhingra K, Kubicek V and Logothetis NK (November-2012): Diffusion of conventional and calcium sensitive MRI contrast agents in the rat cerebral cortex, Fifth Annual World Molecular Imaging Congress (WMIC 2012), Dublin, Ireland, Molecular Imaging and Biology, 14(Supplement 2) S1544.
Keliris A, Mamedov I, Hagberg GE, Logothetis NK, Scheffler K and Engelmann J (November-2012): Dual 1H/19F MR imaging approach for detection of enzyme activity, Fifth Annual World Molecular Imaging Congress (WMIC 2012), Dublin, Ireland, Molecular Imaging and Biology, 14(Supplement 2) S1235.
Hagberg GE, Mamedov I, Placidi M, Keliris A, Merkle H, Logothetis NK and Scheffler K (October-29-2012): 19F-Lanthanide complexes: T1- and T2-dependent signal gain using gradient echoes, ENCITE Symposium "Red hot MRI: In vivo 19F imaging", Nijmegen, The Netherlands.
Cassara AM, Körber R, Burghoff M, Hagberg G, Maraviglia B and Hartwig S (August-2012): Phase Imaging at Ultra-Low Field MRI, 18th International Conference on Biomagnetism (BIOMAG 2012), Paris, France.
Hagberg GE, Mamedov I, Power A, Beyerlein M, Merkle H, Angelovski G and Logothetis NK (May-9-2012): Diffusion in the extra-cellular space of the rat cerebral cortex probed by MRI and direct infusion of contrast agents, 20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia.
Mamedov I, Engelmann J, Hagberg G, Eschenko O and Logothetis NK (May-8-2012): Development of multimodal imaging probes for neuroanatomical connectivity studies in vivo by means of MRI, 20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia.
Hagberg GE, Balla D, Wiesner HM and Logothetis NK (May-9-2011): Small-Scale Phase & Magnitude Fluctuations in fMRI Time Series, 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montréal, Canada.
Bianciardi M, Cerasa A and Hagberg G (June-2003): How experimental design and first-level filtering influence efficiency in second-level analysis of event-related fMRI data, 9th International Conference on Functional Mapping of the Human Brain (HBM 2003), New York, NY, USA, NeuroImage, 19(2 Supplement) e1503-e1504.

Talks (20):

Bause J, Aghaeifar A, Hagberg G, Engel E-M, Avdievitch N, Scheffler K and Pohmann R (September-11-2017) Abstract Talk: 350 μm Isotropic Whole-Brain MP2RAGE without Averaging, ISMRM Workshop on Motion Correction in MRI & MRS (MoCor 2017), Cape Town, South Africa.
Tuzzi E, Hagberg G, Balla D, Loureiro J, Neumann M, Laske C, Pohmann R and Valverde M (April-27-2017) Abstract Talk: In-vivo and ex-vivo R2* and Quantitative Susceptibility Mapping in Alzheimer’s Disease at Ultra-High Magnetic Field compared to Histology, 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017), Honolulu, HI, USA 677-678.
Martin P, Hagberg G, Loureiro J, Bause J, Lerche H, Focke N and Scheffler K (October-1-2016) Abstract Talk: Can 9.4 T MRI improve lesion visualization in epilepsy patients?, 33rd Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB 2016), Wien, Austria, Magnetic Resonance Materials in Physics, Biology and Medicine, 29(Supplement 1) S347-S348.
Loureiro J, Hagberg G, Tuzzi E, Himmelbach M, Ethofer T, Grodd W, Martin P, Valverde M, Pohmann R and Scheffler K (October-1-2016) Abstract Talk: In-vivo ultra-high resolution structural imaging of the human superior colliculus at 9.4T: validation with ex vivo measurements at 9.4T and 14T, 33rd Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB 2016), Wien, Austria, Magnetic Resonance Materials in Physics, Biology and Medicine, 29(Supplement 1) S376-S377.
Tuzzi E, Hagberg G, Balla DZ, Loureiro J, Neumann M, Laske C, Pohmann R, Valverde M and Scheffler K (September-30-2016) Abstract Talk: Ex-vivo and in-vivo ultra-High-Field R2* and QSM microimaging in Alzheimer’s disease, 33rd Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB 2016), Wien, Austria, Magnetic Resonance Materials in Physics, Biology and Medicine, 29(Supplement 1) S144-S145.
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Last updated: Monday, 22.05.2017