Dr. Anke Henning

Address: Max-Planck-Ring 11
72076 Tübingen
Room number: 1.B.02
Phone: +49 7071 601 723
Fax: +49 7071 601 702
E-Mail: Anke.Henning


Picture of Henning, Anke, Dr.

Anke Henning

Position: Research Group Leader  Unit: Henning Scheffler

Magnetic Resonance Spectroscopy (MRS) allows for non-invasive and non-ionizing determination of tissue concentrations and metabolic turn-over rates of various metabolites and compounds in animals or humans. MRS is hence applied for clinical diagnostics and has established as an important tool for physiological research. The focus of this research group is MRS methods development exploiting the advantages of ultra-high field strength and applications in the areas of psychiatric imaging and spinal cord pathologies.


06.2012 – now

Research Group Leader

Max-Planck Institute for Biological Cybernetics, Tübingen, Germany

06.2011 – 09.2011

Visiting scientist

University Medical Center Utrecht, Netherlands

05.2008 - now

Project leader

Institute for Biomedical Engineering, University and ETH, Zurich, Switzerland

04.2004 - 04.2008

Institute for Biomedical Engineering, Swiss Federal Institute of Technology (ETH)

10.1996 – 04.2002 Master of Physics

Technical University Chemnitz, Chemnitz, Germany

09.1999 - 05.2000

Exchange year

State University of New York in Binghamton, USA



Herder-Gymnasium Stralsund, Germany

Full CV

Funding ID

Invited Lectures

Full List of Publications

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Articles (79):

Fuchs A, Boesiger P, Schulte RF and Henning A (February-2014) ProFit revisited Magnetic Resonance in Medicine 71(2) 458–468.
Hock A, Henning A, Boesiger P and Kollias S (September-2013) 1H-MR Spectroscopy in the Human Spinal Cord American Journal of Neuroradiology 34(9) 1682-1689.
Chen X, Boesiger P and Henning A (September-2013) J-refocused 1H PRESS DEPT for localized 13C MR Spectroscopy NMR in Biomedicine 26(9) 1113–1124.
Hock A, MacMillan EL, Fuchs A, Kreis R, Boesiger P, Kollias SS and Henning A (May-2013) Non-water-suppressed proton MR spectroscopy improves spectral quality in the human spinal cord Magnetic Resonance in Medicine 69(5) 1253–1260.
Hock A, Fuchs A, Boesiger P, Kollias SS and Henning A (March-2013) Electrocardiogram-triggered, higher order, projection-based B0 shimming allows for fast and reproducible shim convergence in spinal cord 1H MRS NMR in Biomedicine 26(3) 329–335.
Fuchs A, Luttje M, Boesiger P and Henning A (March-2013) SPECIAL semi-LASER with lipid artifact compensation for 1H MRS at 7 T Magnetic Resonance in Medicine 69(3) 603–612.
Scheidegger M, Walter M, Lehmann M, Metzger C, Grimm S, Boeker H, Boesiger P and Henning A (September-2012) Ketamine Decreases Resting State Functional Network Connectivity in Healthy Subjects: Implications for Antidepressant Drug Action PLoS ONE 7(9) 1-9.
Chen X, Pavan M, Heinzer-Schweizer S, Boesiger P and Henning A (January-2012) Optically transmitted and inductively coupled electric reference to access in vivo concentrations for quantitative proton-decoupled 13C magnetic resonance spectroscopy Magnetic Resonance in Medicine 67(1) 1–7.
Kelm BM, Kaster FO, Henning A, Weber M-A, Bachert P, Boesiger P, Hamprecht FA and Menze BH (January-2012) Using spatial prior knowledge in the spectral fitting of MRS images NMR in Biomedicine 25(1) 1–13.
Item F, Heinzer-Schweizer S, Wyss M, Fontana P, Lehmann R, Henning A, Weber M, Boesiger P, Boutellier U and Toigo M (July-2011) Mitochondrial capacity is affected by glycemic status in young untrained women with type 1 diabetes but is not impaired relative to healthy untrained women American Journal of Physiology 301(1) R60-R66.
MacMillan EL, Chong DGQ, Dreher W, Henning A, Boesch C and Kreis R (May-2011) Magnetization exchange with water and T1 relaxation of the downfield resonances in human brain spectra at 3.0 T Magnetic Resonance in Medicine 65(5) 1239–1246.
Abozguia K, Elliott P, McKenna W, Phan TT, Nallur-Shivu G, Ahmed I, Maher AR, Kaur K, Taylor J, Henning A, Ashrafian H, Watkins H and Frenneaux M (October-2010) The metabolic modulator Perhexiline Corrects Energy Deficiency and Improves Exercise Capacity in Symptomatic Hypertrophic Cardiomyopathy Circulation 122(16) 1562-1569.
Heinzer-Schweizer S, De Zanche N, Pavan M, Mens G, Sturzenegger U, Henning A and Boesiger P (May-2010) In-vivo assessment of tissue metabolite levels using 1H MRS and the Electric REference To access In vivo Concentrations (ERETIC) method NMR in Biomedicine 23(4) 406–413.
Shivu GN, Phan TT, Abozguia K, Ahmed I, Wagenmakers A, Henning A, Narendran P, Stevens M and Frenneaux M (March-2010) Relationship Between Coronary Microvascular Dysfunction and Cardiac Energetics Impairment in Type 1 Diabetes Mellitus Circulation 121(10) 1209-1215.
Nallur Shivu G, Abozguia K, Phan TT, Ahmed I, Henning A and Frenneaux M (February-2010) 31P magnetic resonance spectroscopy to measure in vivo cardiac energetics in normal myocardium and hypertrophic cardiomyopathy: Experiences at 3 T European Journal of Radiology 73(2) 255–259.
Akhvlediani T, Henning A, Sandor PS, Boesiger P and Jung HH (February-2010) Adaptive metabolic changes in CADASIL white matter Journal of Neurology 257(2) 171-177.
Henning A, Fuchs A, Murdoch JB and Boesiger P (August-2009) Slice-selective FID acquisition, localized by outer volume suppression (FIDLOVS) for 1H-MRSI of the human brain at 7 T with minimal signal loss NMR in Biomedicine 122(7) 683–696.
Phan TT, Abozguia K, Nallur Shivu G, Mahadevan G, Ahmed I, Williams L, Dwivedi G, Patel K, Steendijk P, Ashrafian H, Henning A and Frenneaux M (July-2009) Heart Failure With Preserved Ejection Fraction Is Characterized by Dynamic Impairment of Active Relaxation and Contraction of the Left Ventricle on Exercise and Associated With Myocardial Energy Deficiency Journal of the American College of Cardiology 54(5) 402–409.
Walter M, Henning A, Grimm S, Schulte RF, Beck J, Dydak U, Schnepf B, Boeker H, Boesiger P and Northoff G (May-2009) The Relationship Between Aberrant Neuronal Activation in the Pregenual Anterior Cingulate, Altered Glutamatergic Metabolism, and Anhedonia in Major Depression Archives of General Psychiatry 66(5) 478-486.
Wilm BJ, Gamper U, Henning A, Pruessmann KP, Kollias SS and Boesiger P (February-2009) Diffusion-weighted imaging of the entire spinal cord NMR in Biomedicine 22(2) 174–181.
Henning A, Schär M, Kollias SS, Boesiger P and Dydak U (June-2008) Quantitative magnetic resonance spectroscopy in the entire human cervical spinal cord and beyond at 3T Magnetic Resonance in Medicine 59(6) 1250–1258.
Henning A, Schär M, Schulte RF, Wilm B, Pruessmann KP and Boesiger P (January-2008) SELOVS: Brain MRSI localization based on highly selective T1- and B1-insensitive outer-volume suppression at 3T Magnetic Resonance in Medicine 59(1) 40–51.
Northoff G, Walter M, Schulte RF, Beck J, Dydak U, Henning A, Boeker H, Grimm S and Boesiger P (December-2007) GABA concentrations in the human anterior cingulate cortex predict negative BOLD responses in fMRI Nature Neuroscience 10(12) 1515-1517.
Akhvlediani T, Sandor PS, Henning A, Schaller A, Jauslin M, Gallati S, Boesiger P and Jung HH (October-2007) Mitochondrial Encephalopathy with CADASIL-Like MRI European Neurology 58(3) 185–188.
Schulte RF, Henning A, Tsao J, Boesiger P and Pruessmann KP (June-2007) Design of broadband RF pulses with polynomial-phase response Journal of Magnetic Resonance 186(2) 167–175.
Wilm BJ, Svensson J, Henning A, Pruessmann KP, Boesiger P and Kollias SS (March-2007) Reduced field-of-view MRI using outer volume suppression for spinal cord diffusion imaging Magnetic Resonance in Medicine 57(3) 625–630.
Vitali F, Henning A, Oberstrass FC, Hargous Y, Auweter SD, Erat M and Allain FH-T (January-2006) Structure of the two most C-terminal RNA recognition motifs of PTB using segmental isotope labeling EMBO Journal 25(1) 150-162.
Oberstrass FC, Auweter SD, Erat M, Hargous Y, Henning A, Wenter P, Reymond L, Amir-Ahmady B, Pitsch S, Black DL and Allain FH-T (September-2005) Structure of PTB Bound to RNA: Specific Binding and Implications for Splicing Regulation Science 309(5743) 2054-2057.
Filonenko O, Falke M, Hortenbach H, Henning A, Beddies G and Hinneberg H-J (April-2004) Structure of thin CrSi2 films on Si(0 0 1) Applied Surface Science 227(1-4) 341–348.

Conference papers (5):

Pfrommer A and Henning A (September-2017) On the Superlinear Increase of the Ultimate Intrinsic Signal-to-Noise Ratio with Regard to Main Magnetic Field Strength in a Spherical Sample, International Conference on Electromagnetics in Advanced Applications (ICEAA 2017), IEEE, Piscataway, NJ, USA, 684-687.
Pfrommer A and Henning A (May-2015) Optimal Arrangement of Finite Element Loop Arrays for Parallel Magnetic Resonance Imaging in the Human Head at 400 MHz, IEEE MTT-S International Microwave Symposium (IMS 2015), IEEE, Piscataway, NJ, USA, 1-4.
Chang Y-C, Avdievich N and Henning A (August-2014) System Identification and Signal Processing for PID Control of B0 Shim Systems in Ultra-High Field Magnetic Resonance Applications, 19th World Congress of the International Federation of Automatic Control (IFAC World 2014), Pergamon Press, Oxford, UK, IFAC Proceedings Volumes, 47(3), 7517-7522.
Handwerker J, Ortmanns M, Anders J, Eschelbach M, Chang P, Henning A and Scheffler K (November-2013) An active TX/RX NMR probe for real-time monitoring of MRI field imperfections, IEEE Biomedical Circuits and Systems Conference (BioCAS 2013), IEEE, Piscataway, NJ, USA, 194-197.
Morris JE, Wu F, Radehaus C, Hietschold M, Henning A, Hofmann K and Kiesow A (October-2004) Single electron transistors: modeling and fabrication, 7th International Conference on Solid-State and Integrated-Circuit Technology (ICSICT 2004), IEEE Press, Piscataway, NJ, USA, 634-639.

Contributions to books (4):

Giapitzakis IA and Henning A: MRS Sequences and Protocols, -. In: Clinical MR Spectroscopy, (Ed) J. McNulty, Springer International Publishing, Cham, Switzerland, (February-2018). in press
Henning A: Advanced Spectral Quantification: Parameter Handling, Nonparametric Pattern Modeling, and Multidimensional Fitting, 981–994. In: eMagRes, (Ed) R. Wasylishen, Wiley, Hoboken, NJ, USA, (March-2016).
Henning A: In Vivo 1H MRS Applications, 1077–1084. In: Encyclopedia of Spectroscopy and Spectrometry Vol. 2, (Ed) J.C. Lindon, Elsevier, Amsterdam, Netherlands, (2010).
Henning A: In Vivo 1H MRS Methods, 1085–1098. In: Encyclopedia of spectroscopy and spectrometry Vol. 2, (Ed) J.C. Lindon, Elsevier, Amsterdam, Netherlands, (2010).

Posters (190):

Aghaeifar A, Chang P, Nassirpour S, Eschelbach M, Henning A and Scheffler K (June-19-2018): A true comparison of B0 shimming with a very high order spherical harmonic based setup and a multicoil shim array, Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.
Pfrommer A and Henning A (June-19-2018): About the Ideal Receive Array for Human Head MRI, Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.
Wyss P, Zweers P, Brust A, Funk C, Berger M and Henning A (June-19-2018): Magnetic Resonance Spectroscopy biomarkers predict patient outcome in subacute spinal cord injury, Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.
Chang P, Nassirpour S and Henning A (June-19-2018): Measuring Eddy Currents Induced by Switching Gradient/Shim Currents, Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.
Nassirpour S, Chang P and Henning A (June-19-2018): Over-discretized SENSE reconstruction and B0 correction for accelerated non-lipid suppressed 1H FID MRSI of the human brain at 9.4T, Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.
Ziegs T and Henning A (June-19-2018): Simulation of 13C labeling Effects of Glutamate and Glutamine in 1H MR Spectra with different Pulse Sequences at 9.4 T, Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.
Nassirpour S, Chang P, Avdievitch N and Henning A (June-19-2018): SNR Requirements for Successful Application of Compressed Sensing Acceleration to Non-lipid suppressed 1H MRSI at Ultra-High Fields, Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.
Murali Manohar SV, Borbath T, Fichtner N, Giapitzakis IA, Zaldivar D, Kreis R and Henning A (June-18-2018): Estimation of T2 Relaxation Times of Downfield Peaks in Human Brain at 9.4 T, Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.
Chang P, Nassirpour S and Henning A (June-18-2018): Highly Accelerated (R=14) Water Reference Acquisition for High Resolution 1H MRSI using Compressed Sensing, Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.
Nassirpour S, Chang P and Henning A (June-18-2018): MultiNet PyGRAPPA: A Novel Method for Highly Accelerated Metabolite Mapping, Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.
Wright AM, Nassirpour S, Chang P and Henning A (June-18-2018): Toward Absolute Quantification Using External Reference Standards at 3T and 9.4T, Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.
Geldschläger O, Shao T and Henning A (June-18-2018): Universal Parallel Transmit Pulse Design for Local Excitation, Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.
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Last updated: Monday, 22.05.2017