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Alexander Zien

 

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Alexander Zien

Position: Wissenschaftler  Abteilung: 

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Bücher (1):

Chapelle O, Schölkopf B und Zien A: Semi-Supervised Learning, 508, MIT Press, Cambridge, MA, USA, (2006). ISBN: 0-262-25589-8

Artikel (22):

Schweikert G, Zien A, Zeller G, Behr J, Dieterich C, Ong CS, Philips P, De Bona F, Hartmann L, Bohlen A, Krüger N, Sonnenburg S und Rätsch G (November-2009) mGene: Accurate SVM-based gene finding with an application to nematode genomes Genome Research 19(11) 2133-2143.
Schweikert G, Behr J, Zien A, Zeller G, Ong CS, Sonnenburg S und Rätsch G (Juli-2009) mGene.web: a web service for accurate computational gene finding Nucleic Acids Research 37(Supplement 2) W312-W316.
Sonnenburg S, Zien A, Philips P und Rärsch G (Juli-2008) POIMs: positional oligomer importance matrices - understanding support vector machine-based signal detectors Bioinformatics 24(13) i6-i14.
Zien A, Gebhard PM, Fundel K und Aigner T (Juli-2007) Phenotyping of Chondrocytes In Vivo and In Vitro Using cDNA Array Technology Clinical Orthopaedics and Related Research 460 226-233.
Aigner T, Fundel K, Saas J, Gebhard PM, Haag J, Weiss T, Zien A, Obermayr F, Zimmer R und Bartnik E (Oktober-2006) Large-Scale Gene Expression Profiling Reveals Major Pathogenetic Pathways of Cartilage Degeneration in Osteoarthritis Arthritis and Rheumatism 54(11) 3533-3544.
Aigner T, McKenna L, Zien A, Fan Z, Gebhard P und Zimmer R (August-2005) Gene expression profiling of serum- and interleukin-1β-stimulated primary human adult articular chondrocytes: A molecular analysis based on chondrocytes isolated from one donor Cytokine 31(3) 227-240.
Schorle C, Finger F, Zien A, Block J, Gebhard P und Aigner T (August-2005) Phenotypic characterization of chondrosarcoma-derived cell lines Cancer Letters 226(2) 143-154.
Aigner T, Finger F, Zien A und Bartnik E (April-2004) cDNA-Microarrays in der Knorpelforschung: Funktionale Genomik der Osteoarthrose [cDNA-Microarray Technology in Cartilage Research: Functional Genomics of Osteoarthritis) Zeitschrift für Orthopädie und ihre Grenzgebiete 142(2) 241-247.
Finger F, Schorle C, Söder S, Zien A, Goldring MB und Aigner T (2004) Phenotypic Characterization of Human Chondrocyte Cell Line C-20/A4: A Comparison between Monolayer and Alginate Suspension Culture Cells Tissues Organs 178(2) 65-77.
Finger F, Schorle C, Zien A, Gebhard P, Goldring MB und Aigner T (Dezember-2003) Molecular phenotyping of human chondrocyte cell lines T/C-28a2, T/C-28a4, and C-28/I2 Arthritis & Rheumatism 48(12) 3395-3403.
Becker AJ, Chen J, Zien A, Sochivko D, Normann S, Schramm J, Elger CE, Wiestler OD und Blumcke I (November-2003) Correlated stage- and subfield-associated hippocampal gene expression patterns in experimental and human temporal lobe epilepsy European Journal of Neuroscience 18(10) 2792-2802.
Knorr T, Obermayr F, Bartnik E, Zien A und Aigner T (Oktober-2003) YKL-39 (chitinase 3-like protein 2), but not YKL-40 (chitinase 3-like protein 1), is up regulated in osteoarthritic chondrocytes Annals of the Rheumatic Diseases 62(10) 995-998.
Aigner T, Zien A, Hanisch D und Zimmer R (2003) Gene expression in chondrocytes assessed with use of microarrays Journal of Bone and Joint Surgery 85(Suppl 2) 117-123.
Zien A, Fluck J, Zimmer R und Lengauer T (2003) Microarrays: How Many Do You Need? Journal of Computational Biology 10(3-4) 653-667.
Aigner T, Bartnik E, Zien A und Zimmer R (September-2002) Functional Genomics of Osteoarthritis Pharmacogenomics 3(5) 635-650.
Hanisch D, Zien A, Zimmer R und Lengauer T (Juli-2002) Co-Clustering of Biological Networks and Gene Expression Data Bioinformatics (Suppl 1) 145S-154S.
Sommer I, Zien A, von Ohsen N, Zimmer R und Lengauer T (Juni-2002) Confidence measures for protein fold recognition Bioinformatics 18(6) 802-812.
Aigner T, Zien A, Gehrsitz A, Gebhard PM und McKenna L (Dezember-2001) Anabolic and Catabolic Gene Expression Pattern Analysis in Normal Versus Osteoarthritic Cartilage Using Complementary DNA-Array Technology Arthritis and Rheumatism 44(12) 2777-2789.
Zien A, Aigner T, Zimmer R und Lengauer T (Juni-2001) Centralization: A new method for the normalization of gene expression data Bioinformatics 17 S323-S331.
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Zien A, Zimmer R und Lengauer T (November-2000) A Simple Iterative Approach to Parameter Optimization Journal of Computational Biology 7(3,4) 483-501.
Zien A, Küffner R, Mevissen T, Zimmer R und Lengauer T (Oktober-2000) Identification of Drug Target Proteins ERCIM News 43 16-17.
Zien A, Rätsch G, Mika S, Schölkopf B, Lengauer T und Müller K-R (September-2000) Engineering Support Vector Machine Kernels That Recognize Translation Initiation Sites Bioinformatics 16(9) 799-807.

Beiträge zu Tagungsbänden (14):

Franc V, Zien A und Schölkopf B (Juli-2011) Support Vector Machines as Probabilistic Models, 28th International Conference on Machine Learning (ICML 2011), International Machine Learning Society, Madison, WI, USA, 665-672.
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Ong CS und Zien A (September-2008) An Automated Combination of Kernels for Predicting Protein Subcellular Localization In: Algorithms in Bioinformatics, , 8th Workshop on Algorithms in Bioinformatics (WABI 2008), Springer, Berlin, Germany, 186-197, Series: Lecture Notes in Computer Science ; 5251.
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Zien A und Ong CS (Juni-2007) Multiclass Multiple Kernel Learning, 24th Annual International Conference on Machine Learning (ICML 2007), ACM Press, New York, NY, USA, 1191-1198.
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Zien A, Bona FD und Ong CS (Juni-2007) Training and Approximation of a Primal Multiclass Support Vector Machine, 12th International Conference on Applied Stochastic Models and Data Analysis (ASMDA 2007), 1-8.
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Zien A, Brefeld U und Scheffer T (Juni-2007) Transductive Support Vector Machines for Structured Variables, 24th Annual International Conference on Machine Learning (ICML 2007), ACM Press, New York, NY, USA, 1183-1190.
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Sonnenburg S, Zien A und Rätsch G (Juli-2006) ARTS: Accurate Recognition of Transcription Starts in Human, 14th International Conference on Intelligent Systems for Molecular Biology (ISMB 2006), Bioinformatics, 22(14), e472-e480.
Chapelle O, Chi M und Zien A (Juni-2006) A Continuation Method for Semi-Supervised SVMs, 23rd International Conference on Machine Learning (ICML 2006), ACM Press, New York, NY, USA, 185-192.
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Zien A und Candela JQ (August-2005) Large Margin Non-Linear Embedding, 22nd International Conference on Machine Learning (ICML 2005), ACM Press, New York, NY, USA, 1065-1072.
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Chapelle O und Zien A (Januar-2005) Semi-Supervised Classification by Low Density Separation, Tenth International Workshop on Artificial Intelligence and Statistics (AISTATS 2005), Society for Artificial Intelligence and Statistics, Fort Lauderdale, FL, USA, 57-64.
BakIr G, Zien A und Tsuda K (September-2004) Learning to Find Graph Pre-Images In: Pattern Recognition, , 26th Annual Symposium of the German Association for Pattern Recognition (DAGM 2004), Springer, Berlin, Germany, 253-261, Series: Lecture Notes in Computer Science ; 3175.
Eichhorn J, Tolias AS, Zien A, Kuss M, Rasmussen CE, Weston J, Logothetis NK und Schölkopf B (Juni-2004) Prediction on Spike Data Using Kernel Algorithms In: Advances in Neural Information Processing Systems 16, , Seventeenth Annual Conference on Neural Information Processing Systems (NIPS 2003), MIT Press, Cambridge, MA, USA, 1367-1374.
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Zien A, Fluck J, Zimmer R und Lengauer T (April-2002) Microarrays: How Many Do You Need?, Sixth Annual International Conference on Research in Computational Molecular Biology (RECOMB 2002), ACM Press, New York, NY, USA, 321-330.
Zien A, Küffner R, Zimmer R und Lengauer T (August-2000) Analysis of Gene Expression Data with Pathway Scores, 8th International Conference on Intelligent Systems for Molecular Biology (ISMB 2000), AAAI Press, Menlo Park, CA, USA, 407-417.
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Zien A, Zimmer R und Lengauer T (April-2000) A simple iterative approach to parameter optimization, Fourth Annual Conference on Research in Computational Molecular Biology (RECOMB 2000), ACM Press, New York, NY, USA, 318-327.

Beiträge zu Büchern (6):

Chapelle O, Schölkopf B und Zien A: An Augmented PAC Model for Semi-Supervised Learning, 397-419. In: Semi-supervised Learning, (Ed) O. Chapelle, MIT Press, Cambridge, MA, USA, (2006).
Chapelle O, Schölkopf B und Zien A: Analysis of Benchmarks, 377-393. In: Semi-Supervised Learning, (Ed) O. Chapelle, MIT Press, Cambridge, MA, USA, (2006).
Chapelle O, Schölkopf B und Zien A: Perspectives, 395. In: Semi-Supervised Learning, (Ed) O. Chapelle, MIT Press, Cambridge, MA, USA, (2006).
Chapelle O, Schölkopf B und Zien A: Prediction of Protein Function from Networks, 361-375. In: Semi-Supervised Learning, (Ed) O. Chapelle, MIT Press, Cambridge, MA, USA, (2006).
Zien A: A Primer on Molecular Biology, 3-34. In: Kernel Methods in Computational Biology, (Ed) B. Schölkopf, MIT Press, Cambridge, MA, USA, (August-2004).
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Aigner T, Saas J, Zien A, Zimmer R, Gebhard PM und Knorr T: Analysis of differential gene expression in healthy and osteoarthritic cartilage and isolated chondrocytes by microarray analysis, 109-128. (Ed) M. Sabatini und F. De Ceuninck, Humana Press, (Juli-2004).

Technische Berichte (2):

Zien A, Raetsch G und Ong CS: Towards the Inference of Graphs on Ordered Vertexes, 150, Max Planck Institute for Biological Cybernetics, Tübingen, Germany, (August-2006).
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Zien A und Ong CS: An Automated Combination of Sequence Motif Kernels for Predicting Protein Subcellular Localization, 146, Max Planck Institute for Biological Cybernetics, Tübingen, Germany, (April-2006).
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Poster (3):

De Bona F, Ong C-S, Zien A und Rätsch G (Juli-2007): RNA secondary structure prediction using large margin methods, 15th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB 2007) and 6th European Conference on Computational Biology (ECCB 2007), Wien, Austria.
Zien A und Ong CS (August-2006): An Automated Combination of Sequence Motif Kernels for Protein Subcellular Localization, 14th International Conference on Intelligent Systems for Molecular Biology (ISMB 2006), Fortaleza, Brazil.
Zien A, Rätsch G, Mika S, Schölkopf B, Lemmen C, Smola A, Lengauer T und Müller K-R (Oktober-1999): Engineering Support Vector Machine Kernels That Recognize Translation Initiation Sites, German Conference on Bioinformatics (GCB '99), Heidelberg, Germany.

Abschlussarbeiten (1):

Zien A: Computational Analysis of Gene Expression Data, (März-2004). PhD thesis
ISBN ISBN 3-8322-2606-0

Vorträge (7):

Zien A (Juli-2009) Abstract Talk: Mathematical programming for multiple kernellearning, 23rd European Conference on Operational Research (Euro XXIII), Bonn, Germany 155.
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Last updated: Montag, 22.05.2017