Contact

Dr. Xin Yu

Adresse: Spemannstr. 41
72076 Tuebingen
Raum Nummer: 4.B.09
Tel.: 07071 601 740
Fax: 07071 601 701
E-Mail: xin.yu

 

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Xin Yu

Position: Leiter Forschungsgruppe  Abteilung: Yu Scheffler

One research direction is to study the underlying mechanism of neurovascular coupling by identifying the signaling molecules propagating from neuron to glia, and to vessel. The other is to identify the “core switch” underlying the brain arousal and coma states by combining genetic tools with optical imaging and high field fMRI.  The goal is to identify candidate molecules from critical brain nuclei, which can contribute to switch brain states.  We are expected to translate the knowledge acquired from animal models to novel therapeutic treatment of coma patients.

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EDUCATION

 

2007 Ph.D. of Biophysics, Neuroscience, and Physiology, School of Medicine, New York University, USA

2002 Master of Science, Department of Biology, Seton Hall University, USA

2000 Bachelor of Science, Wuhan University, China

 

RESEARCH EXPERIENCE

 

2014-present  Research Group Leader, Max Planck Institute for Biological Cybernetics, Tuebingen, Germany

2008-2013      Research Fellow, National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS), Bethesda, USA

2007-2008      Visiting Postdoctoral Fellow, NIH, NINDS, Bethesda, USA

2002-2007      Research Assistant, Skirball Institute, New York University, New York, USA

2000-2002     Research Assistant/Teaching Assistant, Seton Hall University, South Orange, USA

1998-2000     Research Assistant, Chitin Research Center, Wuhan University, China

 

GRANT-FELLOWSHIP

 

2010-2012 NINDS Competitive Fellowship (equivalent to extramural NRSA): Using MRI to analyze lesion-induced neuroplasticity in rats

 

INVITED TALKS

 

2013    Symposium on High-Field NMR Animal Imaging, Max Planck Institute for Biological Cybernetics, Tuebingen, Germany

2012    Johns Hopkins University School of Medicine, Department of Psychiatry and Behavioral Sciences, Baltimore, MD, USA

2012    Symposium on Brainnetome Meets Genome, University of Queensland, Queensland Brain Institute/Center for Advanced Imaging, Brisbane, Australia,

2011    Peking University, Dept of Biomedical Engineering, Beijing, China

2011    New York University, School of Medicine, Center for Biomedical Imaging, New York, USA

2011    Biomedical Imaging Research Seminar, Weill Medical College of Cornell University, New York, USA

2010    Institute of Neuroscience, Chinese Academy of Sciences, Shanghai, China 2010

2009    Educational Courses of International Society of Magnetic Resonance in Medicine (ISMRM): MRI/MRS of mice.  Honolulu, USA

2008    Gordon Research Conference (Auditory system). New London, USA

 

HONORS AND AWARDS

 

2013  Summa Cum Laude Merit Award (ISMRM), Salt Lake City, USA

2012  Summa Cum Laude Merit Award (ISMRM), Melbourne, Australia

2012  Invited Moderator of the Sunshine Educational Course of ISMRM, Melbourne, Australia

2011  Junior Fellow of the ISMRM

2007  Second Place Poster Award of ISMRM, Berlin, Germany

2007  Banner Bearer of Graduate School of Arts and Sciences of NYU, USA

2007  President’s Service Award (NYU), USA

2005  Philipson Speaker Award (Skirball Institute Annual Retreat), USA

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Vorträge (42):

Wang M, He Y und Yu X (April-24-2017) Abstract Talk: Simultaneous fMRI with GCaMP6-mediated neuronal and astrocytic calcium signal recording, 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017), Honolulu, HI, USA 122.
Yu X (April-3-2017) Abstract Talk: MRI-guided robotic-driven optogenetic fMRI and simultaneous calcium recordings, 28th International Symposium on Cerebral Blood Flow, Metabolism and Function, 13th International Conference on Quantification of Brain Function with PET (BRAIN & BRAIN PET 2017), Berlin, Germany.
Yu X (Februar-22-2017) Abstract Talk: Mapping the vascular dynamic network connectivity with calcium-indicated neural correlates from rodents to humans, 11th ESMI Winter Conference "hot TOPIics in IMaging" (TOPIM 2017), Les Houches, France.
Yu X (September-24-2016) Invited Lecture: Simultaneous fMRI with optogenetics and calcium recordings in rats, Satellite Symposium "Multi-modal fMRI from photons to protons", 5th Biennial Conference on Resting State and Brain Connectivity, Wien, Austria.
Chen X, Chen Y und Yu X (September-8-2016) Abstract Talk: Map optogenetically driven hippocampal activity with simultaneous fMRI and GCaMP-mediated calcium recording, 9th Annual World Molecular Imaging Congress (WMIC 2016), New York, NY, USA, Molecular Imaging and Biology, 18(Supplement 2) S1296-S1297.
Wang M, He Y, Engelmann J und Yu X (September-2016) Abstract Talk: Decipher the neuronal and astrocytic calcium signal coupling with fMRI, 17th Conference of Junior Neuroscientists of Tübingen (NeNa 2016): Neuroscience & Law, Schramberg, Germany 12.
He Y, Pohmann R, Scheffler K, Kleinfeld D, Rosen B und Yu X (September-2016) Abstract Talk: Map task-related and resting-state Vascular Network Connectivity in Rats and Humans, 17th Conference of Junior Neuroscientists of Tübingen (NeNa 2016): Neuroscience & Law, Schramberg, Germany 13.
Yu X (Juli-18-2016) Invited Lecture: Multimodal fMRI of neuro-glio-vascular dynamics in a rat brainstem coma model, Massachusetts General Hospital: Department of Neurology, Boston, MA, USA.
Chen X-M, Merkle H und Yu X (Mai-10-2016) Abstract Talk: Light-driven single-vessel fMRI on the rat hippocampus, 24th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2016), Singapore(0480).
Yu X (März-31-2016) Invited Lecture: When Photons meet Protons: Probe light inside the rat brain for single-vessel fMRI and its translational potential, 1st CENIR-MRI Workshop on Transtaltional Research with Multi-Modal Imaging, Paris, France.
Yu X (November-20-2015) Keynote Lecture: Probe light inside the rat brain for single‐vessel fMRI with optic, 18. Jahrestagung der Deutschen Sektion der ISMRM e.V. (DS ISMRM 2015), Münster, Germany.
Yu X (November-4-2015) Invited Lecture: Probe light inside the rat brain for single-vessel fMRI under 14T, Chinese Academy of Sciences: Institute of Automation: Brainnetome Lecture Series, Beijing, China.
Pais Roldán P, Singh A, Merkle H, Schulz H und Yu X (Juni-3-2015) Abstract Talk: Sensing the high magnetic field: Fusion of otoliths in zebrafish larvae entails a hint, 23rd Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2015), Toronto, Canada(0695).
He Y, Merkle H und Yu X (Juni-2-2015) Abstract Talk: Single Venule Multi-Echo Line-Scanning fMRI (MELS-fMRI), 23rd Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2015), Toronto, Canada(0361).
Yu X (März-20-2015) Invited Lecture: High-field single-vessel fMRI in the deep layer cortex of rats, 10th Annual Meeting of the European Society for Molecular Imaging (EMIM 2015), Tübingen, Germany(631).
Yu X (Dezember-16-2014) Invited Lecture: Map the rat brain under light with fMRI, Johannes Gutenberg-Universität Mainz: Collaborative Research Center 1080, Mainz, Germany.
Yu X (Juli-30-2014) Invited Lecture: Push limits and extend boundaries of small animal fMRI, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, USA.
Yu X (Juli-29-2014) Invited Lecture: Decipher the Vascular Neural Network in the Rat Brain with Single-Vessel fMRI and Optogenetics, Gordon Research Conference: In Vivo Magnetic Resonance: From Molecules to Humans, Andover, NH, USA.
Yu X (Juni-27-2014) Invited Lecture: Targeting Projection Fibers for Optogenetics and fMRI: Is anti-dromic activity a concern?, Lectures on MR: fMRI and optogenetics: Probing networks in the animal brain, Münster, Germany.
Yu X (Juni-26-2014) Invited Lecture: MEMRI Animal Brain Mapping: local uptake vs. track tracing, Lectures on MR: fMRI and optogenetics: Probing networks in the animal brain, Münster, Germany.
Yu X, Dodd S und Koretsky AP (April-25-2013) Abstract Talk: Targeting Projection Fibers for Optogenetics and fMRI, 21st Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT, USA 1531.
Yu X, Qian C, Chen D-Y, Dodd S und Koretsky AP (April-23-2013) Abstract Talk: Laminar Specificity of fMRI Onset Times Distinguishes Top Down from Bottom Up Neural Inputs Mediating Cortical Plasiticty, 21st Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT, USA 904.
Yu X, Dodd S und Koretsky AP (Mai-10-2012) Abstract Talk: Functional MRI Demonstrates a Novel Role for Callosal Function to Protect Deprived Barrel Cortex from Adjacent Cortical Takeover by Plasiticy in Rodent Brain, 20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia(660).
Yu X, Chung S, Wang S, Dodd S, Walters J, Isaac J und Koretsky A (Mai-9-2011) Abstract Talk: Strengthening of Thalamocortical Synapses at Layer IV in the Juvenile Whisker Barrel Measured by MRI & Electrophysiology, 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montréal, Canada 100.
Yu X, Dodd S, Hirano Y, Glen D, Saad ZS, Reynolds RC, Silva AC und Koretsky AP (Mai-4-2010) Abstract Talk: Mapping the early spatiotemporal BOLD fMRI response in the barrel cortex of rats, ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden(267).
Yu X, Dodd SJ, Chung S, Isaac J, Walters JR und Koretsky AP (Mai-3-2010) Abstract Talk: Unilateral Infraorbital Denervation Leads to Plasticity in the Rat Whisker Barrel Cortex, ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden(11).
Yu X, Wang S, Dodd S, Chen D-Y und Koretsky A (April-23-2009) Abstract Talk: Functional MRI of Somatosensory Cortical Reorganization in the Rat Brain, 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM 2009), Honolulu, HI, USA(692).
Yu X, Dodd S, Goloshevsky A, Silva A und Koretsky A (Juni-28-2008) Invited Lecture: BOLD-fMRI of the auditory system in rats, Gordon-Kenan Research Seminar: Auditory System (GRS), New London, NH, USA.
Yu X, Sudarov A, Zaim YW, Joyner AL und Turnbull DH (Mai-23-2007) Abstract Talk: MEMRI Reveals Functional Alterations in the Auditory Midbrain of Fgf17 Knockout Mice, 2007 Joint Annual Meeting ISMRM-ESMRMB, Berlin, Germany 99.
Yu X, Sanes DH, Zou J, Aristizabal O, Zaim YW und Turnbull DH (Mai-23-2007) Abstract Talk: MEMRI Reveals Plasticity Changes in the Auditory Midbrains of Mice After Two-Tone Rearing, 2007 Joint Annual Meeting ISMRM-ESMRMB, Berlin, Germany 480.
Yu X, Sanes D, Zou J, Wadghiri YZ und Turnbull D (Mai-9-2006) Abstract Talk: Statistical mapping of auditory activity by Manganese enhanced MRI, 14th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2006), Seattle, WA, USA 54.
Yu X, Wadghiri YZ, Sanes DH und Turnbull DH (November-16-2005) Abstract Talk: Tonotopic mapping of the mouse auditory midbrain with Mn-enhanced MRI, 35th Annual Meeting of the Society for Neuroscience (Neuroscience 2005), Washington, DC, USA(816.9).
Yu X, Wadghiri YZ, Sanes DH und Turnbull DH (Mai-11-2005) Abstract Talk: Tonotopic mapping of the mouse auditory midbrain with Mn-enhanced MRI, 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2005), Miami Beach, FL, USA 91.
Yu X, Wadghiri YZ, Sanes DH und Turnbull DH (Mai-20-2004) Abstract Talk: Mn-Enhanced MRI (MEMRI) of auditory brain activity in unilaterally deafened mice, 12th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2004), Kyoto, Japan(639) 139.
Yu X, Wadghiri YZ, Moreno C, Sanes DH und Turnbull DH (Juli-14-2003) Abstract Talk: Mn-Enhanced MRI of Neural Activity in the mouse Midbrain, 11th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2003), Toronto, Canada(495) 112.
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Last updated: Montag, 22.05.2017