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New publication in Inorganic Chemistry

Montag 17.07.2017 10:00

We performed a detailed study of the solution structure and water exchange rate of a previously reported Eu(III) complex and its analogue. The chemical exchange saturation transfer (CEST) spectra were recorded at different temperatures and saturation powers, revealing presence of two CEST-active isomers with coordinated water molecules having similar chemical shifts. Upon assessment of the exchange rates using conventional quantification methods, we concluded that presence of different species should be carefully treated and analyzed to avoid erroneous determination of water exchange rates.

Opens external link in new windowLink to the article: N. Cakić, B. Tickner, M. Zaiss, D. Esteban-Gómez, C. Platas-Iglesias, G. Angelovski. ”Spectrally Undiscerned Isomers Might Lead to Erroneous Determination of Water Exchange Rates of paraCEST Eu(III) Agents.” Inorg. Chem. 2017, 56, 7737-7745.




Last updated: Montag, 03.11.2014